Pin1 regulation of prosurvival signalling in eosinophils

Pin1 对嗜酸性粒细胞中促生存信号的调节

• 批准号: 8368155
• 负责人: James S Malter
• 金额: $ 19.65万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-05 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8368155
• 关键词: 1-Phosphatidylinositol 3-Kinase; Adrenal Cortex Hormones; Affinity; Allergens; Animal Model; Apoptosis; Apoptotic; Asthma; Binding; Binding Proteins; Biology; Breathing; Cell Cycle Progression; Cell Surface Receptors; Cells; Chronic; Cyclophilin A; Data; Development; Enzymes; Exposure to; Family; Fibrosis; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Factor; Health; Immune; Inflammation; Interleukin-3; Interleukin-5; Isomerase; Life; Lung; MAP Kinase Gene; Mediating; Messenger RNA; Metabolism; Molecular Conformation; Morbidity - disease rate; Nerve Degeneration; Participant; Pathway interactions; Peptides; Peptidylprolyl Isomerase; Pharmaceutical Preparations; Phenotype; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Pneumonia; Process; Production; Proline; Proteins; Pulmonary Eosinophilia; RNA Decay; Regulation; Resistance; Respiratory physiology; Role; Signal Transduction; Tacrolimus Binding Protein 1A; Tissues; airway remodeling; chemokine; cis trans isomerization; cytokine; drug development; eosinophil; eosinophilic inflammation; mRNA Stability; parvulin; prevent; pro-caspase-8; repaired; response; tumorigenesis