Administrative Core A

行政核心A

基本信息

批准号：
10388086
负责人：
GERARD DAVID SCHELLENBERG
金额：
$ 52.04万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-04-15 至 2026-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10388086
关键词：
Abbreviations Alzheimer&apos s Disease Alzheimer&apos s Disease Core Center Alzheimer&apos s disease related dementia Artificial Intelligence Award Chromatin Collaborations Communities Consent Data Data Analyses Data Protection Data Set Development Disease Documentation Ensure Epigenetic Process European Fostering Frontotemporal Dementia Funding Genetic Genetic Diseases Genome Genomics Grant Health Sciences Institution Institutional Review Boards International Joints Lead Lewy Body Disease Machine Learning Meta-Analysis Methods Molecular Molecular Conformation National Institute on Aging Newsletter Paralysed Parkinson&apos s Dementia Pathogenesis Pick Disease of the Brain Principal Investigator Process Progressive Supranuclear Palsy Proteomics Protocols documentation Provider Publications Quality Control Reporter Research Research Personnel SNP array Schedule Site Source Systems Analysis Teleconferences Telephone United States National Institutes of Health University Health Services Variant Work cognitive system computerized data processing corticobasal degeneration dashboard data harmonization data sharing data storage site database of Genotypes and Phenotypes deep learning deep neural network exome follow-up functional genomics gene discovery genomic data meetings member metabolomics neural network neuroimaging phenotypic data single-cell RNA sequencing symposium trait web site whole genome working group

项目摘要

Core A Project Summary/Abstract Core A (Administrative Core) will oversee, facilitate and coordinate all GCAD activities carried out by the other two cores. Core A will also coordinate analyses by investigators funded to analyze Alzheimer’s Disease Sequencing Project (ADSP) data. Core A Specific Aims are: (1) Coordinate acquisition of ADRD genetic, FG, and phenotype data; (2) Coordinate data processing, harmonization and analyses; (3) Support/foster collaboration between ADSP investigators and related projects; (4) Disseminate data and findings to a diverse group of ADRD researchers; (5) Provide administrative support to GCAD including governance, Institution Review Board (IRB) protocol review, and data sharing compliance.

核心 A 项目总结/摘要核心 A（行政核心）将监督、促进和协调 GCAD 开展的所有活动核心 A 还将协调由其他两个核心资助的研究人员进行的分析。分析阿尔茨海默病测序项目 (ADSP) 数据的核心 A 具体目标是：(1) ADRD遗传、FG和表型数据的坐标获取；（2）坐标数据； (3) 支持/促进ADSP之间的合作研究人员和相关项目；(4) 向 ADRD 的不同群体传播数据和研究结果； (5) 为 GCAD 提供行政支持，包括治理、机构审查委员会 (IRB) 协议审查和数据共享合规性。