Core 3-Biostatistics

核心3-生物统计学

基本信息

批准号：
10208807
负责人：
J. Jack LEE
金额：
$ 24.52万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-16 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10208807
关键词：
Address Adopted Algorithms Animal Model Award Bioconductor Bioinformatics Biological Markers Biometry Cancer Center Cell Line Clinical Clinical Data Clinical Research Clinical Trials Clinical Trials Design Code Complex Computer Analysis Conduct Clinical Trials Confidentiality of Patient Information Data Data Analyses Databases Development Ensure Epidemiology Experimental Designs Genomics Human Resources Immunologics Laboratories Libraries Link Manuscripts Methods Pathology Patients Phase Play Proteomics Publications Reporting Research Research Personnel Research Project Grants Resources Role Services Statistical Data Interpretation Statistical Methods Structure Technology University of Texas M D Anderson Cancer Center base bioinformatics resource biomarker discovery career clinical database data management design experimental study genome analysis genomic data high dimensionality innovation laboratory experiment meetings melanoma member novel open source pre-clinical predictive marker programs sound tissue resource tool translational study trial design web-accessible

项目摘要

Core 3: Project Summary/Abstract The Biostatistics and Bioinformatics Core 3 provides comprehensive service to guide design of experiments, to optimize quantitative data analysis, and to maintain statistical justification and interpretation of results. Specifically, Core 3 will implement sound experimental design principles that are tailored to address specific scientific questions for each project. Core 3 will also carry out data analyses using suitable statistical methods and bioinformatics algorithms, and will contribute to the interpretation of results through written reports and frequent interactions with project investigators. Whenever appropriate, Core 3 will develop new analysis tools to address new challenges in the analysis of various data, especially high-throughput genomic and proteomic data. Members of Core 3 will participate in monthly SPORE meetings with all project investigators, ensuring that statistical and data analysis/management issues are carefully considered during all phases of each SPORE experiment. Thus, from inception to reporting and publication, basic laboratory and translational experiments will benefit from the SPORE program that will be used to augment existing MD Anderson Cancer Center biostatistics resources.

核心 3：项目总结/摘要生物统计学和生物信息学核心 3 提供全面的服务来指导设计实验，优化定量数据分析，并保持统计合理性和解释结果。具体来说，Core 3 将实施健全的实验设计原则，旨在解决每个项目的具体科学问题。 Core 3 还将使用适当的统计方法进行数据分析方法和生物信息学算法，并将有助于通过书面形式解释结果报告以及与项目调查人员的频繁互动。在适当的时候，Core 3 将开发新的分析工具可应对各种数据分析中的新挑战，特别是高通量基因组数据和蛋白质组数据。 Core 3 的成员将参加所有项目的每月 SPORE 会议调查人员，确保在调查过程中仔细考虑统计和数据分析/管理问题每个 SPORE 实验的所有阶段。因此，从开始到报告和出版，基础实验室转化实验将受益于 SPORE 计划，该计划将用于增强现有的 MD 安德森癌症中心生物统计资源。