RCMI@Morgan: Center for Urban Health Disparities Research and Innovation

RCMI@摩根：城市健康差异研究与创新中心

基本信息

批准号：
10372114
负责人：
JAMES M WACHIRA
金额：
$ 47.73万
依托单位：
MORGAN STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-31 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10372114
关键词：
Address Animal Experimentation Animal Housing Animal Testing Animals Area Arts Baltimore Basic Science Behavioral Sciences Bioinformatics Biology Biomedical Research Biometry Cardiovascular Diseases Communicable Diseases Community Health Complex Computers and Advanced Instrumentation Consultations Core Facility Data Data Analyses Decision Making Diabetes Mellitus Disease Economic Development Educational workshop Engineering Ensure Environment Faculty Fee Schedules Flow Cytometry Funding Future Genes Genetic Genomics Health Health Disparities Research Health Policy Health Promotion Histology Human Resources Infrastructure Institutes Interdisciplinary Study Laboratories Laboratory Animals Lead Leadership Maintenance Molecular Analysis Molecular and Cellular Biology Operative Surgical Procedures Outcome Pathology Persons Pilot Projects Psychology Public Health Public Health Informatics Publications Reporting Research Research Infrastructure Research Personnel Research Support Resources Role Schools Science Services Site Social Interaction Social Work Structure Students Training Training Programs Training and Education United States National Institutes of Health Universities Update Veterinarians Work addiction base behavioral study college community involvement computing resources experimental study food security health disparity health inequalities innovation instrumentation interest meetings member molecular imaging multidisciplinary nanomaterials new technology notch protein operation outreach research and development research facility therapy development tool urban health disparities urban setting

项目摘要

Project Summary Health disparities are attributable to complex diseases that involve the interactions of social, environmental, and genetic factors. A better understanding of the mechanisms of the diseases and the development of interventions requires state-of-the-art research facilities that support top notch, multidisciplinary research and the involvement of the community. The Research Infrastructure Core (RIC) will provide the administrative structure, instrumentation, and expertise needed to perform multidisciplinary biomedical and health disparities research in the urban setting of Baltimore. Based on the current and future research needs at Morgan State University, three Core Research Facilities (CRFs) will be established or enhanced: 1) Animal Research Core (ARC); 2. Molecular and Cellular Biology Research Core Laboratory (MCB); and 3. Biostatistics and Bioinformatics Support Unit (BBSU). To meet the needs of both behavioral and basic science researchers, the ARC will consist of two separate sites. It will be managed by a faculty Co-Lead and a Core Manager. It will provide animal housing and testing rooms and advanced instrumentation for histology/pathology, surgery, and behavioral studies. A veterinary doctor from Johns Hopkins University will serve as the ARC's to oversee the health of research animals. The MCB will comprise of multiple laboratories in the Dixon Research Center and it will be managed by a Co-Lead and a Core Manager. It will provide support for genomics, flow cytometry, molecular imaging, molecular analyses, nanomaterials research, and other cutting-edge experiments. The BBSU will be managed by a faculty Co-Lead who will be assisted by a Faculty Bioinformatician. It will offer statistical and bioinformatics consultation and computational resources to researchers. The BBSU will be housed in an RCMI office area in Portage. The three CRFs will conduct outreach, regular training workshops, and will promote the dissemination of research findings through publications and by assisting users with data analyses. The CRFs will belong to the University as shared facilities for use by any MSU researcher. An Oversight Committee consisting of the Vice President for Research and Economic Development (DRED) and the deans of the schools (Engineering, Sciences, and Social Work) and colleges (Community Health and Policy and Liberal Arts) of participating faculty will provide guidance to the PI and RIC Lead on matters relating to major purchases, space allocations, facilities, and personnel changes. It will advise the president and provost on the biomedical research needs of the university and facilitate the sustainability of the CRFs beyond the RCMI funding period. The PI will discuss CRFs' operations with the Lead and Co-Leads regularly and the Lead and Co-Leads will meet monthly and as necessary to review progress towards meeting the objectives of the RIC, resolve any problems, and to strategize on how to enhance and sustain research in the different areas of interest. The resources, training programs, and outreach efforts to faculty and other users will serve to entrench competitive research in health and health disparities at Morgan State University.

项目概要健康差异是由涉及社会、环境和社会因素相互作用的复杂疾病造成的。遗传因素。更好地了解疾病的机制和干预措施的发展需要最先进的研究设施来支持一流的多学科研究和参与社区的。研究基础设施核心（RIC）将提供管理结构，进行多学科生物医学和健康差异研究所需的仪器和专业知识巴尔的摩的城市环境。根据摩根州立大学当前和未来的研究需求，三将建立或加强核心研究设施（CRF）： 1）动物研究核心（ARC）； 2. 分子和细胞生物学研究核心实验室（MCB）； 3. 生物统计学和生物信息学支持单位（BBSU）。为了满足行为和基础科学研究人员的需求，ARC 将由两个部分组成：单独的站点。它将由一名教职联席主管和一名核心经理管理。它将提供动物住房和用于组织学/病理学、手术和行为研究的测试室和先进仪器。一个约翰·霍普金斯大学的兽医将担任 ARC 监督研究的健康状况动物。 MCB 将由迪克森研究中心的多个实验室组成，并将由其管理由联合领导和核心经理组成。它将为基因组学、流式细胞术、分子成像、分子分析、纳米材料研究和其他尖端实验。 BBSU将被管理由一名教员共同领导，并由一名教员生物信息学家协助。它将提供统计和生物信息学为研究人员提供咨询和计算资源。 BBSU 将设在 RCMI 办公区波蒂奇。三个 CRF 将开展外展活动、定期举办培训研讨会，并促进传播通过出版物和协助用户进行数据分析来了解研究结果。 CRF 将属于大学作为可供任何密歇根州立大学研究人员使用的共享设施。由副主任组成的监督委员会研究与经济发展主席 (DRED) 和各学院院长（工程、科学、社会工作）和参与教师的学院（社区健康、政策和文科）将就重大采购、空间分配、设施、以及人事变动。它将就生物医学研究需求向总统和教务长提供建议大学并促进 CRF 在 RCMI 资助期之后的可持续性。 PI 将讨论 CRF 定期与牵头人和联合牵头人一起开展业务，牵头人和联合牵头人将每月举行一次会议有必要审查实现 RIC 目标的进展情况、解决任何问题并制定战略关于如何加强和维持不同感兴趣领域的研究。资源、培训计划、对教师和其他用户的推广工作将有助于巩固健康和健康领域的竞争性研究摩根州立大学的差距。