Initiative to Maximize Research Education in Genomics: Diversity Action Plan (DAP)

最大化基因组学研究教育的倡议：多样性行动计划（DAP）

基本信息

批准号：
10205135
负责人：
RICHARD A GIBBS
金额：
$ 29.97万
依托单位：
BAYLOR COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-19 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10205135
关键词：
Address African American African American student Area Atmosphere Award Bachelor&apos s Degree Behavioral Research Bioinformatics Biological Sciences Biomedical Research Clinical Research Competence Country Critical Thinking Data Doctor of Philosophy Doctor&apos s Degree Educational Activities Educational Curriculum Engineering Faculty Foundations Funding Genetic Genetic Variation Genomics Goals Graduate Education Health Hispanics Human Human Genetics Human Genome Project Institution Internships Intervention Journals Knowledge Lead Medicine Minority Minority Groups Molecular Genetics National Human Genome Research Institute Native Americans Outcome Recording of previous events Research Research Training STEM career STEM field Schools Science Science, Technology, Engineering and Mathematics Scientist Students Training Training Activity Training Programs Training and Education Underrepresented Populations United States Visit base career college education research educational atmosphere experience graduate student human disease human genome sequencing improved innovation interest intervention program next generation pre-doctoral prevent programs recruit skills student participation success successful intervention summer internship summer research summer student therapy development undergraduate student

项目摘要

Project Summary/Abstract The United States (US) science, technology, engineering, and mathematics (STEM) workforce has been a world leader in biomedical research for decades, and in the 21st century the US took the lead in sequencing the human genome. The STEM workforce has also faced the challenge of increasing participation of under-represented (UR) populations to remain competitive in science and engineering. The National Human Genome Research Institute (NHGRI) had the foresight from the outset of the Human Genome Project to include training (Diversity Action Plan-DAP) that would address this shortage as the field developed. In spite of many national interventions, several minority groups remain underrepresented at all degree and professional career levels.1-2 For example, of the 76,447 doctorate degrees awarded in the biological sciences in 2012, only 3,677 (4.8%) were African Americans, 4,463 (5.8%) were Hispanics, and 314 (0.41%) were Native Americans. 1 Therefore, the development of intervention programs seeking to ameliorate these disparities within science research become important and necessary. The long term goal of this proposal is to increase UR PhDs in genomics and bioinformatics. We will approach this goal in two specific aims. Aim 1 will provide six undergraduate and 8 post-baccalaureate students DI training activities that result in 75% completing the program with greater genomics/bioinformatics knowledge and lab-based critical thinking skills appropriate for success in graduate school. Although the number of UR PhDs is low in biomedical research, in the field of bioinformatics there is a shortage of US trained scientists in this area and the UR groups are even more severely limited in this new field. Aim 2 plans to recruit and retain 50% of DI trainees as graduate students in the Molecular and Human Genetics Department at Baylor College of Medicine. The African American applicant pool is lowest among all under-represented groups that apply to the MHG department. We will address these aims, using research training as our foundation, in the HGSC-DI summer research internship and Post-baccalaureate programs. Our program data indicates the following DI results: 72% of our post-baccalaureate students enter PhD programs; 100% of pre-doctoral alumni are retained in PhD programs; and 100% of the summer interns obtain bachelor's degrees. We have proven ability to recruit and retain students in STEM. The overall impact of this proposal will increase the number of UR PhDs in genomics and trained in bioinformatics.

项目概要/摘要美国 (US) 的科学、技术、工程和数学 (STEM) 劳动力已几十年来，美国在生物医学研究方面一直处于世界领先地位，进入21世纪，美国在生物医学研究方面处于领先地位对人类基因组进行测序。 STEM 劳动力也面临着增加的挑战代表性不足（UR）人群的参与，以保持科学和工程领域的竞争力。这美国国家人类基因组研究所（NHGRI）从人类基因组研究伊始就具有远见。基因组计划将包括培训（多样性行动计划-DAP），以解决这一短缺问题领域发达。尽管采取了许多国家干预措施，一些少数群体的代表性仍然不足 1-2 例如，在授予的 76,447 个博士学位中 2012 年生物科学领域，只有 3,677 名（4.8%）非裔美国人，4,463 名（5.8%）西班牙裔， 314 人（0.41%）是美洲原住民。 1 因此，制定干预方案寻求改善科学研究中的这些差异变得重要且必要。该提案的长期目标是增加UR基因组学和生物信息学方面的博士学位。我们将通过两个具体目标来实现这一目标。目标 1 将提供 6 名本科生和 8 名学士后学生学生 DI 培训活动使 75% 的学生以更高的成绩完成了课程适合成功的基因组学/生物信息学知识和基于实验室的批判性思维技能研究所。尽管生物医学研究领域的 UR 博士数量较少，但在生物信息学领域缺乏美国训练有素的科学家，而 UR 小组则更缺乏在这个新领域受到严重限制。 Aim 2 计划招募并保留 50% 的 DI 学员作为研究生在贝勒医学院分子和人类遗传学系。非裔美国人在所有向 MHG 部门提出申请的代表性不足的群体中，申请人数是最低的。我们将在 HGSC-DI 夏季研究中，以研究培训为基础来实现这些目标实习和学士学位后课程。我们的计划数据表明以下 DI 结果：72% 我们的学士后学生进入博士课程； 100%博士前校友留任博士课程；暑期实习生100%获得学士学位。我们有被证明的能力招募和留住 STEM 学生。该提案的总体影响将增加 UR 的数量基因组学博士并接受过生物信息学培训。