Penn mental health AIDS research center

宾夕法尼亚大学心理健康艾滋病研究中心

基本信息

批准号：
9987943
负责人：
DWIGHT L. EVANS
金额：
$ 16.2万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-06-03 至 2023-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9987943
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adult Aging Area Basic Science Behavior Therapy Behavioral Behavioral Mechanisms Behavioral Sciences Biological Biological Sciences Biology Biometry Botswana Caring Characteristics Child Chronobiology Clinical Cognitive Therapy Collaborations Combined Modality Therapy Communities Comorbidity Complement Continuity of Patient Care Contracts Development Diabetes Mellitus Disease Elderly Evidence based intervention Evidence based practice Faculty Fostering Funding Gender Goals Grant HIV HIV Infections HIV Seropositivity HIV risk Immune System Diseases Immunology Incidence Individual Institutes Institution International Journals Leadership Life Cycle Stages Link Medical Mental Health Mental disorders Mentally Ill Persons Mentors Metabolism Methodology Mission National Institute of Mental Health Neurobiology Obesity Outcome Pediatric Hospitals Pennsylvania Persons Pharmacotherapy Philadelphia Pilot Projects Population Postdoctoral Fellow Pregnant Women Productivity Psychiatry Public Health Public Policy Research Research Personnel Research Priority Research Training Resource Sharing Resources Risk Scientific Inquiry Services Sleep Social Sciences Specimen Substance abuse problem Talents Training Translations Treatment outcome Underrepresented Minority United States National Institutes of Health Universities Woman Work antiretroviral therapy base behavioral health circadian collaboratory cultural competence data management design health disparity implementation science improved infection risk innovation microbiome next generation novel novel strategies organizational structure pre-doctoral programs psychologic recruit repository secondary infection senior faculty sex success synergism theories treatment optimization young woman

项目摘要

Overview Abstract/Summary The overarching theme of the Penn Mental Health AIDS Research Center (PMHARC) at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP) is to transform how individuals with comorbid mental illness/AIDS are treated and managed by developing innovative, interdisciplinary, and integrative approaches to optimize psychiatric, behavioral, and medical outcomes and achieving a better understanding of the biological, psychological, and behavioral mechanisms underlying these combined illnesses and treatments. No other center in the U.S. is currently pursuing this explicit focus, making PMHARC unique in the NIMH ARC portfolio. A substantial body of work links psychiatric disorders to acquisition of HIV infection, accelerated immune dysfunction, poor access to HIV care, and poor adherence to antiretroviral treatment once in care. Yet, there is a relative paucity of evidence-based interventions focused on the combined treatment of mental illness/AIDS and related medical co-morbidities, and relatively little work in determining the relationships between mental health treatment and HIV/AIDS disease and understanding the underlying biology. PMHARC will stimulate novel approaches and strategies to address these problems by providing mentoring and resource support for both new and established investigators choosing to study comorbid mental illness/AIDS, in part through innovative pilot studies. PMHARC's leadership has extensive expertise in contemporary pharmacotherapy of mental illness and AIDS, cognitive behavioral treatments, and theory-based behavioral interventions. PMHARC will extend well-established collaborations at Penn and CHOP, including those in the Department of Psychiatry and the CFAR, as well as with the CTSA/CTRC, the Delaney Collaboratory, and community partners in Philadelphia. A unique feature of PMHARC is the collaboration of well- established mental health AIDS researchers, well-established mental health researchers who have not previously studied AIDS, well-established substance abuse AIDS researchers who have not previously studied mental health, and AIDS researchers not previously focused on mental health. PMHARC has an Administrative and Developmental Core, and four Shared Resource Cores.

概述摘要/总结宾夕法尼亚州心理健康艾滋病研究中心 (PMHARC) 的总体主题宾夕法尼亚大学 (Penn) 和费城儿童医院 (CHOP) 改变共病精神疾病/艾滋病患者的治疗和管理方式开发创新、跨学科和综合的方法来优化精神科、行为和医疗结果，并更好地了解生物学、这些综合疾病背后的心理和行为机制治疗。目前美国没有其他中心在追求这一明确的重点，使得 PMHARC 在 NIMH ARC 产品组合中独一无二。大量工作与精神病学有关 HIV 感染的障碍、加速免疫功能障碍、难以获得 HIV 护理，并且在护理后抗逆转录病毒治疗的依从性较差。但数量相对较少侧重于精神疾病/艾滋病联合治疗的循证干预措施相关的医疗共存疾病，并且在确定之间的关系方面相对较少的工作心理健康治疗和艾滋病毒/艾滋病疾病以及了解潜在的生物学。 PMHARC 将激发新的方法和策略来解决这些问题为新老研究者选择提供指导和资源支持研究共病精神疾病/艾滋病，部分通过创新试点研究。 PMHARC 的领导层在当代精神疾病药物治疗方面拥有丰富的专业知识，艾滋病、认知行为治疗和基于理论的行为干预。 PMHARC 将扩大宾夕法尼亚大学和 CHOP 的良好合作关系，包括与精神病学和 CFAR，以及 CTSA/CTRC、Delaney Collaboratory 和费城的社区合作伙伴。 PMHARC 的一个独特功能是良好的协作成熟的心理健康艾滋病研究人员，成熟的心理健康研究人员以前没有研究过艾滋病，公认的药物滥用艾滋病研究人员以前没有研究过心理健康，艾滋病研究人员以前没有关注过心理健康。 PMHARC 有一个行政和发展核心，以及四个共享核心资源核心。