Penn mental health AIDS research center

宾夕法尼亚大学心理健康艾滋病研究中心

基本信息

批准号：
8670020
负责人：
DWIGHT L. EVANS
金额：
$ 155.66万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-06-03 至 2018-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8670020
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adolescent Adult Anti-Retroviral Agents Area Basic Science Behavior Therapy Behavioral Behavioral Mechanisms Behavioral Research Behavioral Sciences Biological Biology Biometry Caring Child Clinical Clinical Research Clinical Sciences Cognitive Therapy Collaborations Combined Modality Therapy Communities Community Mental Health Centers Community Outreach Comorbidity Complement Contracts Development Discipline Disease Education Education and Outreach Elderly Evaluation Evidence based intervention Evidence based practice Extramural Activities Faculty Fostering Funding Goals HIV HIV Infections Immune System Diseases Individual Institutes Institution Interdisciplinary Study Leadership Life Cycle Stages Link Medical Mental Health Mental disorders Mentally Ill Persons Mentors Mission Monitor National Institute of Mental Health Outcome Patients Pediatric Hospitals Pennsylvania Persons Pharmacotherapy Philadelphia Pilot Projects Population Postdoctoral Fellow Pregnant Women Process Productivity Psychiatry Public Health Relative (related person)Research Research Activity Research Infrastructure Research Personnel Resource Sharing Resources Risk Schools Strategic Planning Substance abuse problem Sum Talents Translational Research Treatment outcome Underrepresented Minority Universities Woman Work base data management design improved innovation novel novel strategies organizational structure outreach program pre-doctoral programs psychologic public health relevance ranpirnase research study secondary infection theories

项目摘要

DESCRIPTION (provided by applicant): The overarching theme of the proposed Penn Mental Health AIDS Research Center (PMHARC) at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP) is to transform how individuals with comorbid mental illness/AIDS are treated and managed by developing innovative, interdisciplinary, and integrative approaches to optimize psychiatric, behavioral, and medical outcomes and achieving a better understanding of the biological, psychological, and behavioral mechanisms underlying these combined illnesses and treatments. No other center in the U.S. is currently pursuing this explicit focus, making PMHARC unique in the NIMH ARC portfolio. A substantial body of work links psychiatric disorders to acquisition of HIV infection, accelerated immune dysfunction, poor access to HIV care, and poor adherence to antiretroviral treatment once in care. Yet, there is a relative paucity of evidence-based interventions focused on the combined treatment of mental illness/AIDS and related medical co-morbidities, and relatively little work in determining the relationships between mental health treatment and HIV/AIDS disease and understanding the underlying biology. PMHARC will stimulate novel approaches and strategies to address these problems by providing mentoring and resource support for both new and established investigators choosing to study comorbid mental illness/AIDS, in part through innovative pilot studies. PMHARC's leadership has extensive expertise in contemporary pharmacotherapy of mental illness and AIDS, cognitive behavioral treatments, and theory-based behavioral interventions. PMHARC will extend well-established collaborations at Penn and CHOP, including those in the Department of Psychiatry and Penn Center for AIDS Research (CFAR), as well as with community partners in Philadelphia. A unique feature of PMHARC is the collaboration of well-established mental health AIDS researchers, well-established mental health researchers who have not previously studied AIDS, well-established substance abuse AIDS researchers who have not previously studied mental health, and AIDS researchers not previously focused on mental health. PMHARC will have an Administrative and Developmental Core, and four Shared Resource Cores.

描述（由申请人提供）：宾夕法尼亚大学 (Penn) 和费城儿童医院 (CHOP) 拟议的宾夕法尼亚精神健康艾滋病研究中心 (PMHARC) 的总体主题是改变患有共病精神疾病/艾滋病的个人的生活方式通过开发创新的、跨学科的和综合的方法来治疗和管理，以优化精神、行为和医疗结果，并更好地理解这些组合疾病和治疗背后的生物、心理和行为机制。目前美国没有其他中心在追求这一明确的重点，这使得 PMHARC 在 NIMH ARC 产品组合中独一无二。大量研究工作将精神疾病与艾滋病毒感染、加速免疫功能障碍、获得艾滋病毒护理的机会不佳以及入院后抗逆转录病毒治疗的依从性差联系起来。然而，针对精神疾病/艾滋病及相关医学共病的综合治疗的循证干预措施相对较少，在确定精神健康治疗与艾滋病毒/艾滋病疾病之间的关系以及了解其根本原因方面的工作也相对较少。生物学。 PMHARC 将通过创新的试点研究，为选择研究共病精神疾病/艾滋病的新老研究者提供指导和资源支持，从而激发新的方法和策略来解决这些问题。 PMHARC 的领导层在当代精神疾病和艾滋病药物治疗、认知行为治疗和基于理论的行为干预方面拥有广泛的专业知识。 PMHARC 将扩大宾夕法尼亚大学和 CHOP 的良好合作关系，包括精神病学系和宾夕法尼亚艾滋病研究中心 (CFAR) 以及费城的社区合作伙伴。 PMHARC 的一个独特功能是与知名的心理健康艾滋病研究人员、以前没有研究过艾滋病的知名心理健康研究人员、以前没有研究过心理健康的知名药物滥用艾滋病研究人员以及以前没有研究过艾滋病的研究人员进行合作。专注于心理健康。 PMHARC 将拥有一个管理和开发核心以及四个共享资源核心。