Etiology of Childhood Obesity: A Longitudinal Study

儿童肥胖的病因学：一项纵向研究

• 批准号: 7645811
• 负责人: Leslie A. Lytle
• 金额: $ 54.98万
• 依托单位: SEATTLE CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7645811
• 关键词: Address; Adolescence; Age; Anthropometry; Behavior; Behavioral; Biological; Biological Factors; Birth Weight; Blood Chemical Analysis; Blood Glucose; Blood Pressure; Body Composition; Body mass index; Breast Feeding; Centers for Disease Control and Prevention (U.S.); Child; Chronic Disease; Code; Communities; Data; Data Set; Demographic Factors; Development; Diet; Distal; Eating; Economics; Ensure; Environment; Environmental Risk Factor; Epidemic; Ethnic Origin; Etiology; Family; Family history of; Fasting; Food; Funding; Future; Gender; Glean; Grant; Growth; Health; Height; Hip region structure; Home environment; Individual; Information Systems; Intake; Intervention; Life; Longitudinal Studies; Measurement; Measures; Mediating; Methodology; Methods; Modeling; Neighborhoods; Non-Insulin-Dependent Diabetes Mellitus; Nutrient; Obesity; Obesity associated disease; Overweight; Parents; Pattern; Physical activity; Physical environment; Policies; Predictive Factor; Preventive; Psychosocial Factor; Race; Recruitment Activity; Research; Research Personnel; Restaurants; Risk; Risk Factors; Sampling; Schools; Science; Socioeconomic Status; Syndrome; Testing; Time; Walking; Weight; Work; Youth; blood lipid; cardiovascular risk factor; cohort; contextual factors; demographics; experience; fast food; feeding; follow-up; health disparity; interest; modifiable risk; multidisciplinary; obesity in children; preference; prevent; psychosocial; racial and ethnic; social; socioeconomics; theories

DESCRIPTION (provided by applicant): The purpose of the Etiology of Childhood Obesity (ECHO) study is to examine the etiology of childhood obesity using a socio-ecological approach considering possible risk and protective factors at individual, family, school, and neighborhood levels. Obesity in adolescence is related to increased cardiovascular risk in adulthood. Approximately 60% of overweight youth have one CVD risk factor and another 25% have more than one risk factor. We will recruit 400 youth between the ages of 10 and 13 and one of their biological parents, conduct measurements and follow them for two years. We will target our recruitment to include youth who are at risk for, or who are overweight (at or above the 85th percentile of BMI using the CDC growth curves) and those who are in the recommended weight range and will over sample by zip code to ensure economic and racial/ethnic diversity. Individual measures on youth will include fasting blood glucose, blood lipids, anthropometry, blood pressure, and psychosocial, preference and socioeconomic status, family history related to weight including child's birth weight, early feeding (practices such as breast-feeding, family history of obesity and obesity-related chronic disease), family meal and activity patterns, and the home food and activity environments. We will measure the height, weight, waist and hip circumference of both of the youth's biological parents. For each youth in the study, we will collect data on their school environment including opportunities for physical activity, food options available in the school cafeteria and throughout the school, and school food and activity policies. Neighborhood level measures will be obtained using Geographical Information System (GIS) methodologies to assess obesogenic environmental factors such as the presence of walking and bike paths, convenience stores and fast food restaurants proximal to each youth's home and school. This research is timely and important because it will: 1) identify obesogenic factors at multiple levels of the environment guided by a social-ecological theoretical framework; 2) include a diverse sample of youth from a large, urban community; 3)'focus on modifiable risk and protective factors and use state of the science methods to measure them; 4) be directed by an experienced and multidisciplinary team of investigators; and 5) provide essential information for multi-level interventions to prevent childhood obesity.

描述（由申请人提供）：儿童肥胖症（ECHO）研究的目的是使用一种社会生态学方法来检查儿童肥胖的病因，考虑到个人，家庭，学校和邻里水平的可能风险和保护因素。青春期的肥胖与成年后的心血管风险增加有关。大约60％的超重青年患有一个CVD危险因素，另外25％的危险因素多于一个。我们将在10至13岁之间招募400名年轻人，并招募其中一名亲生父母，进行测量并关注两年。我们将针对我们的招聘，包括有可能有风险或超重的年轻人（使用CDC增长曲线的BMI的第85个百分点）以及在推荐体重范围内的年轻人，并将按邮政编码进行样本以确保经济和种族/种族多样性。对青年的个人措施将包括禁食血糖，血脂，人体测量，血压以及心理社会，偏好和社会经济状况，与体重有关的家族史，包括儿童的出生体重，早期喂养（例如母乳喂养，肥胖和肥胖症的家族史，与肥胖相关的慢性疾病），家庭饮食和活动方式和家庭食品和家庭食品和活动环境和活动环境和活动环境和活动环境。我们将测量两个年轻人的亲生父母的身高，体重，腰部和臀部。对于研究中的每个年轻人，我们将收集有关他们学校环境的数据，包括体育锻炼的机会，学校自助餐厅和整个学校的食物选择以及学校的食物和活动政策。将使用地理信息系统（GIS）方法来获得邻里水平措施，以评估肥胖环境因素，例如靠近每个青年家和学校的步行和自行车道，便利店和快餐店的存在。这项研究是及时和重要的，因为它将：1）以社会生态学理论框架为指导的多个环境中确定肥胖因子； 2）包括来自大型城市社区的青年样本； 3）'专注于可修改的风险和保护因素，并使用科学方法的状态来衡量它们； 4）由经验丰富且多学科的调查员团队指导； 5）提供多层次干预措施的基本信息，以防止儿童肥胖症。