SUPPLEMENTAL INTRAVENOUS IRON THERAPY FOR RLS

不宁腿综合征的补充静脉铁剂治疗

• 批准号: 7607477
• 负责人: CHRISTOPHER J EARLEY
• 金额: $ 0.34万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607477
• 关键词: Affect; Brain; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Functional disorder; Funding; Grant; Institution; Intravenous; Iron; Population; Protocols documentation; Reporting; Research; Research Personnel; Resources; Restless Legs Syndrome; Sleep Disorders; Source; United States National Institutes of Health; ferryl iron; pre-clinical

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Restless legs syndrome (RLS) is a common sleep disorder that is reported to affect between 2 and 5% of the population. Although the pathophysiology of RLS is unknown, there is a significant body of preclinical and clinical research that implicates brain iron deficiency. The PI has an ongoing protocol to investigate the effect of IV iron for the treatment of RLS. The proposed research will assess the efficacy of supplemental IV iron therapy in those that responded to IV iron previously.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 不安的腿综合征（RLS）是一种常见的睡眠障碍，据报道会影响2％至5％的人群。 尽管RLS的病理生理尚不清楚，但仍有大量的临床前和临床研究都暗示脑铁缺乏症。 PI有一个持续的方案来研究IV铁对RLS治疗的影响。拟议的研究将评估以前对IV铁反应的静脉注射疗法的疗效。