CANNABIS AND SCHIZOPHRENIA

大麻和精神分裂症

• 批准号: 7606099
• 负责人: Sanjiv Kumra
• 金额: $ 0.07万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606099
• 关键词: Adolescent; Brain; Brain Part; Cannabis; Cannabis Abuse; Clinical; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Magnetic Resonance Imaging; Neurocognitive; Numbers; Patients; Research; Research Personnel; Resources; Schizophrenia; Source; Structure; Symptoms; United States National Institutes of Health; brain volume; design; white matter

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A number of studies have demonstrated brain structure abnormalities in patients with schizophrenia, as well as in patients with comorbid cannabis abuse. This study is designed to answer the following questions: (1) does cannabis use impact the integrity or volume of brain white matter in the whole brain or in specific parts of the brain in adolescents with schizophrenia or in healthy controls? (2) do the findings from the magnetic resonance imaging studies correlate with neurocognitive findings or clinical symptoms?

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 许多研究表明，精神分裂症患者以及吸食大麻的患者存在大脑结构异常。本研究旨在回答以下问题：（1）大麻的使用是否会影响精神分裂症青少年或健康对照者整个大脑或大脑特定部位的大脑白质的完整性或体积？ (2) 磁共振成像研究的结果与神经认知结果或临床症状相关吗？