Injuries in Children with Autism

自闭症儿童受伤

基本信息

批准号：
9891178
负责人：
GUOHUA LI
金额：
$ 21.67万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-12-16 至 2021-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9891178
关键词：
20 year old 21 year old 8 year old Accident and Emergency department Accidental Injury Admission activity Age Aggressive behavior Attention Attention deficit hyperactivity disorder Behavior Behavioral Cessation of life Characteristics Child Child Welfare Childhood Childhood Injury Clinical Cognitive Data Data Reporting Data Set Databases Development Developmental Disabilities Diagnosis Diagnostic Drowning Educational process of instructing Emergency Department patient Emergency department visit Environment Epidemiology Executive Dysfunction General Population Geographic Locations Health Hospitalization Hospitals Impairment Injury Inpatients Intellectual functioning disability Intentional injury International Classification of Disease Codes International Classification of Diseases Laws Location Longevity Measures Morbidity - disease rate Nursery Schools Parents Patient Self-Report Patients Pattern Perception Population Population Group Prevalence Prevention strategy Preventive Intervention Procedures Reporting Research Risk Risk Factors Rural Safety Sample Size Sampling Self-Injurious Behavior Severities Social Interaction Source Suicide attempt Symptoms Time trend United States Visit Work aged assault autism spectrum disorder autistic children base comorbidity design early childhood effective intervention functional disability high risk population injury prevention interest mortality patient population payment pediatric emergency pediatric patients repetitive behavior sex social social communication surveillance data trauma centers trend

项目摘要

The long-term objective of the proposed project is to reduce injury morbidity and mortality in children with autism spectrum disorders (ASD). The specific aims are to: 1) examine the time trends of injuries treated in emergency departments (EDs) and hospitals among children with ASD aged 0–20 years; 2) characterize the epidemiologic patterns of injuries treated in EDs and hospitals among children with ASD according to age, sex, injury mechanism, intent and severity; and 3) assess the excess risks of injuries treated in EDs and hospitals associated with ASD. The estimated prevalence of ASD continues to rise. Surveillance data in the United States indicate that one in 59 children aged 8 years in 2014 met the diagnostic criteria for ASD and that one in 40 children aged 3 to 17 years had parent-reported ASD diagnosis. Injury has long been recognized as a major cause of morbidity and mortality in children in the United States, resulting in approximately 18,000 deaths with over 9 million emergency department visits and more than 200,000 hospitalizations among children younger than 20 years of age annually. Recent studies indicate that children with ASD may be at exceptionally heightened risk of injury mortality and certain types of injury morbidity, likely due to impairments in social, cognitive and behavioral functioning and common comorbid conditions such as attention deficit hyperactivity disorder and intellectual disability. Research on injury in children with ASD is inadequate and often limited by small sample sizes and self-reported data. Building on our recent work on injury mortality in children with ASD and injuries in preschool age children with ASD, the proposed project aims to close an important research gap by examining the time trends, epidemiologic patterns and excess risks of injuries treated in EDs and hospitals in children with ASD under 21 years of age based on nationally representative samples. We will use the Nationwide Emergency Department Sample for years 2009–2019 and the triennial Kids’ Inpatient Database from 1997 to 2019 to create datasets for pediatric ED patients with a diagnosis of ASD (n ≈ 300,000) and for pediatric inpatients with a diagnosis of ASD (n ≈ 70,000). We will examine the time trends, epidemiologic patterns and excess risks of injuries treated in EDs and hospitals among children with ASD according to injury mechanism, intent, severity, demographic characteristics, comorbid conditions, and geographic regions compared to the general pediatric patient population. Results from the proposed project will inform preventive strategies and facilitate the development of effective interventions to reduce injuries in children with ASD.

拟议项目的长期目标是降低患有以下疾病的儿童的伤害发病率和死亡率自闭症谱系障碍 (ASD) 的具体目标是： 1) 检查治疗损伤的时间趋势。 2) 急诊室 (ED) 和医院对 0-20 岁 ASD 儿童的特征；根据年龄、性别、伤害机制、意图和严重程度；以及 3) 评估在急诊室和医院接受治疗的额外风险与自闭症谱系障碍相关的监测数据显示，美国自闭症谱系障碍的患病率持续上升。各州表示，2014 年，每 59 名 8 岁儿童中就有 1 名符合自闭症谱系障碍 (ASD) 的诊断标准，而 40 名 3 至 17 岁的儿童被家长报告为自闭症谱系障碍 (ASD) 损伤长期以来被认为是一种严重的疾病。导致美国儿童发病和死亡的原因，导致约 18,000 人死亡超过 900 万人次急诊就诊，超过 20 万名年龄较小的儿童住院治疗最近的研究表明，患有自闭症谱系障碍的儿童可能处于异常状态。肉身伤害死亡风险和某些类型的伤害发病率，可能是由于社交、认知和行为功能以及常见的合并症，例如注意力缺陷多动对 ASD 儿童伤害的研究尚不充分，而且常常受到以下因素的限制。基于我们最近关于自闭症谱系障碍儿童伤害死亡率的研究。以及患有自闭症谱系障碍的学龄前儿童的伤害，拟议的项目旨在弥合重要的研究空白通过检查急诊室和医院治疗的时间趋势、流行病学模式和过度风险我们将使用基于全国代表性样本的 21 岁以下 ASD 儿童。 2009-2019 年全国急诊科样本和三年一次的儿童住院数据库从 1997 年到 2019 年，为诊断为 ASD 的儿科 ED 患者 (n ≈ 300,000) 创建数据集诊断为自闭症谱系障碍 (ASD) 的儿科住院患者 (n = 70,000) 我们将检查时间趋势、流行病学。根据伤害情况，自闭症谱系障碍儿童在急诊室和医院接受治疗的伤害模式和超额风险机制、意图、严重程度、人口特征、合并症和地理区域与一般儿科患者群体相比，拟议项目的结果将为预防提供信息。战略并促进制定有效的干预措施，以减少自闭症谱系障碍儿童的伤害。