Developmental Core

发展核心

• 批准号: 7930102
• 负责人: JOHN David HAMILTON
• 金额: $ 49.06万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-15 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7930102
• 关键词: AIDS/HIV problem; Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Advisory Committees; Applications Grants; Area; Award; Caring; Clinical Investigator; Clinical Research; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Commit; Communication; Communities; Complement; Development; Discipline; Effectiveness; Ensure; Environment; Faculty; Financial Support; Fostering; Foundations; Funding; Future; Goals; Grant; HIV; Health; Health Policy; Health Professional; Hepatitis; Human; Human Resources; Institutes; Investigator-Initiated Research; Knowledge; Laboratories; Lead; Leadership; Malignant Neoplasms; Medical; Mentors; Mentorship; Methodology; Mission; Modeling; Oncogenic Viruses; Outcomes Research; Participant; Peer Review; Play; Positioning Attribute; Process; Productivity; Publications; Recruitment Activity; Research; Research Personnel; Research Support; Resource Allocation; Resources; Rewards; Role; Science; Scientist; Strategic Planning; Structure; System; Training; Translational Research; United States National Institutes of Health; Vaccines; Vision; Work; base; behavioral/social science; biomedical scientist; experience; flexibility; global health; innovation; medical schools; meetings; member; multidisciplinary; programs; skills; success; systems research; translational medicine

1. Core Mission The goal of the Developmental Core is to stimulate new investigator-initiated research breakthroughs in HIV/AIDS through the support of CFAR faculty utilizing three major mechanisms; direct financial support to allow recruitment of talented faculty in targeted areas who complement and enhance the CFAR HIV research agenda (Faculty Development); research support through the peer-reviewed Small Grants and Emerging Opportunities Awards; and the fostering of young investigators through a structured training and mentoring program, the Mentored Clinical Research Scientist Program (MCRSP). The MCRSP was initiated in the current cycle of funding, and it will be continued and expanded in the next funding cycle to reach a larger pool of junior trainees engaged in HIV-related research. Ultimately a more formal program in mentoring across the Cores will be developed. Much has been accomplished over the past four years due to the impact of the CFAR Developmental Core in support of HIV/AIDS research. The effectiveness of the Developmental Core is due, in part, to the fact that nearly all HIV-related research at Duke is coordinated and led by the Duke CFAR faculty, resulting in a cohesive research community that is accustomed to working together across academic departmental boundaries to form multidisciplinary and interdepartmental teams. Illustrative of this collaborative environment are the numerous publications co-authored by members of different departments (See Table I and References 1-28 for a listing of key CFAR personnel who are either first or senior authors, and their collaborators, on publications since 2004). The Developmental Core's role in this process has been in the implementation and coordination of the supportive mechanisms defined above. Final decisions concerning the establishment of priorities and allocation of resources resides with the CFAR Executive Committee and CFAR leadership, which allows flexibility in resource allocation to take advantage of opportunities and to correct weaknesses if any. Institutional support in the form of matching funds from the Dean of the School of Medicine has been made available to further enhance CFAR Developmental Core activities, providing additional leveraged resources to expand Faculty Development, and Small Grants and Emerging Opportunities Awards. Thus, as the Duke CFAR moves forward in its second funding cycle, there is a firm foundation of coordination, cooperation and communication among CFAR members, members of the Duke research community at-large who are working on HIV-related projects, and the leadership ofthe School of Medicine.

1。核心任务 发展核心的目的是通过支持CFAR教师利用三种主要机制来刺激新研究者引发的艾滋病毒/艾滋病研究突破；直接的财政支持，以允许在有针对性的地区招募才华横溢的教师，他们补充和增强了CFAR HIV研究议程（教师发展）；通过同行评审的小型赠款和新兴机会奖励的研究支持；以及通过结构化培训和指导计划培养年轻研究人员的指导临床研究科学家计划（MCRSP）。 MCRSP是在当前资金周期中启动的，将在下一个资金周期继续并扩展，以达到从事HIV相关研究的较大的初级学员。最终将开发一个更正式的指导核心计划。 在过去的四年中，由于CFAR发育核心对HIV/AIDS研究的支持，已经完成了很多事情。发展核心的有效性部分是由于以下事实：杜克大学的几乎所有与HIV相关的研究都由Duke CFAR教师协调和领导，这导致了一个具有凝聚力的研究社区 组成多学科和部门间团队的边界。这种协作环境的说明是由不同部门成员共同撰写的众多出版物（有关首先或高级作者及其合作者的关键CFAR人员的列表，请参见表I和参考文献1-28，自2004年以来就在出版物上）。发展核心在此过程中的作用一直在 上述支持机制的实施和协调。有关建立优先级和资源分配的最终决定与CFAR执行委员会和CFAR领导力有关，这允许在资源分配方面灵活地利用机会并纠正弱点。医学院院长的机构支持以匹配资金的形式 已被提供以进一步增强CFAR发展核心活动，提供额外的杠杆资源来扩大教师发展，并提供小额赠款和新兴机会奖励。 因此，随着公爵CFAR在其第二个筹资周期中向前迈进，CFAR成员之间存在着坚定的协调，合作和沟通的基础，杜克大学研究社区的成员一般正在研究与HIV相关的项目，以及医学院的领导。