DNA SEQUENCING AND ANALYSIS CORE FACILITY

DNA 测序和分析核心设施

基本信息

批准号：
7715370
负责人：
KYLE L JOHNSON
金额：
$ 4.37万
依托单位：
UNIVERSITY OF TEXAS EL PASO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-06-01 至 2009-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7715370
关键词：
Arts Biomedical Research Computer Retrieval of Information on Scientific Projects Database Core Facility Custom DNA DNA Sequence DNA analysis Development Electrophoresis Equipment Funding Genomics Genotype Grant Indium Infectious Disease Epidemiology Institution Laboratories Metabolic Diseases Mexico Molecular Epidemiology Polymerase Chain Reaction Research Research Infrastructure Research Personnel Research Project Grants Resources Science Sequence Analysis Source Stress Techniques Texas Time United States National Institutes of Health Universities day instrument toxicant

Arts Biomedical Research Computer Retrieval of Information on Scientific Projects Database Core Facility Custom DNA DNA Sequence DNA analysis Development Electrophoresis Equipment Funding Genomics Genotype Grant Indium Infectious Disease Epidemiology Institution Laboratories Metabolic Diseases Mexico Molecular Epidemiology Polymerase Chain Reaction Research Research Infrastructure Research Personnel Research Project Grants Resources Science Sequence Analysis Source Stress Techniques Texas Time United States National Institutes of Health Universities day instrument toxicant

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项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DNA analysis, particularly the application of the deluge of DNA genomic information, is an essential aspect of modern day biomedical research. In order to facilitate the application of state of the art techniques to research problems relevant to the Texas/Mexico border region, this proposal will support the development of a DNA analysis core facility. This facility will combine existing shared and investigator owned equipment, including DNA sequencing, Genotype analysis, real time PCR, and specialized electrophoresis capability into a managed, researcher accessible core facility. In addition to providing staff support, this proposal will augment existing instrument infrastructure by the addition of a custom microarraying facility. This new custom arraying capability is an essential element in support of development of existing research projects in toxicant stress, the molecular epidemiology of infectious diseases, and metabolic disorders. While the facility will initially be setup in existing space, it will move to expanded quarters in the new Biomedical Sciences Building at the University of Texas in El Paso upon completion of those new laboratories.

该副本是利用众多研究子项目之一由NIH/NCRR资助的中心赠款提供的资源。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构是对于中心，这不一定是调查员的机构。 DNA分析，尤其是DNA基因组信息泛滥的应用，是现代生物医学研究的重要方面。为了促进最先进的技术在研究与德克萨斯/墨西哥边境地区有关的问题上的应用，该提案将支持开发DNA分析核心设施。该设施将将现有的共享和研究者拥有的设备结合在一起，包括DNA测序，基因型分析，实时PCR以及专门的电泳能力与可托管的研究人员可访问的核心设施。除了提供员工支持外，该建议还将通过增加定制的微阵列设施来增强现有的仪器基础设施。这种新的自定义阵列能力是支持毒物压力中现有研究项目的发展，传染病的分子流行病学和代谢性疾病的基本要素。虽然该设施最初将在现有空间中进行设置，但它将在这些新实验室完成后，在德克萨斯大学埃尔帕索大学的新生物医学科学大楼扩展。