ACTIVITY #2 - CENTER FOR MOLECULAR GENETICS AND INFECTIOUS DISEASES RESEARCH

活动

基本信息

批准号：
7715297
负责人：
JOSE R RODRIGUEZ-MEDINA
金额：
$ 68.57万
依托单位：
UNIVERSITY OF PUERTO RICO MED SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-08-01 至 2009-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7715297
关键词：
Acquired Immunodeficiency Syndrome Architecture Area Base Sequence Biological Biological Preservation Biomedical Research Biopsy Blood Cell Line Clinical Clinical Research Collaborations Communicable Diseases Communities Computer Retrieval of Information on Scientific Projects Database Consult DNA Development Educational workshop Environment Funding Goals Grant Hand Human Human Genetics Infectious Diseases Research Information Centers Institution International Laboratories Link Medical Methodology Molecular Biology Molecular Genetics Nucleic acid sequencing Organism Plasma Cells Puerto Rico Purpose RNA Research Research Personnel Resources Sampling Science Scientist Sequence Analysis Services Skin Source Technology Tissue Sample Training Training and Education United States National Institutes of Health Universities Work cell bank genotyping technology health disparity human tissue immortalized cell novel

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Regarding AIDS The long term goal of the Center for Molecular Genetics and Infectious Diseases Research is to develop and strengthen a collaborative research environment that will enable high quality biomedical research in molecular genetics and infectious diseases at the University of Puerto Rico Medical Sciences Campus. The Center will consist of three components: Human Genetics, Infectious Disease and Molecular Biology, with corresponding coordinators working together as a team. Through the proposed Center we will develop the expertise to apply high throughput genotyping technologies, we will train staff in the technology related to the establishment and preservation of immortalized cell lines from human tissue samples for the purpose of research, and make these available to the research community at the MSC. We propose to maintain on-hand and apply novel DNA and RNA isolation methodologies to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general. We propose to accomplish these goals by pursuing the following specific aims of the proposed Center for Molecular Genetics and Infectious Diseases Research: 1. To strengthen the scientific interactions between basic scientists and clinicians from the MSC and to enhance collaborations with international scientists working in molecular biology, human genetics, and infectious diseases; 2. To provide training, education, and support for the development of young scientists as well as established basic and clinical researchers, by offering regular trainings, seminars, and workshops imparted by internationally recognized leaders in the field; 3. To stimulate new scientists, both clinical and basic, to become actively engaged in molecular biology, human genetics, and infectious diseases research; 4. Establish a centralized DNA, plasma and cell banking facility for storage of clinical samples from human blood or skin biopsies for research purposes in molecular genetics; 5. To provide basic core laboratory services in molecular biology, human genetics, and infectious diseases including technical support, consulting, and training; 6. To initiate webcasting of training sessions in specialized areas in collaboration with the "Center for Information Architecture in Research". We will focus these initiatives on externally funded, interdisciplinary, collaborative projects that will enhance the quality of biomedical and clinical research linked to health disparities in Puerto Rico and nationally, at the Medical Sciences Campus.

该副本是利用众多研究子项目之一由NIH/NCRR资助的中心赠款提供的资源。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构是对于中心，这不一定是调查员的机构。关于艾滋病分子遗传学和传染病中心研究的长期目标是开发和增强合作研究环境，该环境将在波多黎各大学医学科学校园内实现高质量的生物医学研究和分子遗传学和传染病。该中心将由三个组成部分组成：人类遗传学，传染病和分子生物学，相应的协调员作为一个团队一起工作。通过拟议的中心，我们将开发专业知识来应用高通量基因分型技术，我们将培训与人类组织样本中不朽的细胞系有关的技术人员，以进行研究，并使MSC的研究社区可用于研究社区。我们建议将新型的DNA和RNA分离方法应用于各种生物和生物样品，以进行核酸序列分析。我们建议通过追求拟议的分子遗传学和感染性疾病中心的以下特定目标来实现这些目标：1。加强基础科学家与临床医生之间的科学互动，并加强与在分子生物学，人类基因和感染性疾病方面的国际科学家合作； 2。通过提供常规的培训，研讨会和研讨会，为该领域的国际认可的领导者提供定期的培训，研讨会和讲习班，为年轻科学家的发展以及建立的基础和临床研究人员提供培训，教育和支持； 3。刺激临床和基础的新科学家，以积极参与分子生物学，人类遗传学和传染病研究； 4。建立一个集中的DNA，血浆和细胞库设备，用于存储人类血液或皮肤活检中的临床样品，以研究分子遗传学的研究。 5。提供分子生物学，人遗传学和传染病在内的基本核心实验室服务，包括技术支持，咨询和培训； 6。与“研究中心架构中心”合作，在专业领域启动培训课程的网络广播。我们将这些举措集中在外部资助的跨学科合作项目上，这些项目将提高与波多黎各和全国医学科学校园中与健康差异有关的生物医学和临床研究的质量。