Predicting complicated grief from grief processing

从悲伤处理中预测复杂的悲伤

• 批准号: 10768365
• 负责人: Noam Schneck
• 金额: $ 5.9万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-16 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10768365
• 关键词: Acute; Cessation of life; Cognitive; Development; Down-Regulation; Early identification; Emotional; Feeling; Goals; Grief reaction; Intervention; Knowledge; Measures; Persons; Process; Resolution; Sampling; Suicide; Testing; Thinking; experience; high risk; intense pain; loved ones; mental representation; neural; recruit; targeted treatment; therapy development

Abstract Most people grieving the loss of a loved one will experience a period of intense pain and focusing on the loss lasting around 6 months, which is known as acute grief. Complicated grief (CG) occurs when the experiences of acute grief extend well past 6-months post-loss. Thoughts and feelings about the loss (i.e. grief processing) occurring during acute grief may play a role in healthy grieving and protect against CG development. Identification of the cognitive and emotional mechanisms of grief processing that contribute to healthy grief resolution would advance knowledge of the goals of grieving and assist the development of interventions for complicated grief. Two core components of grief processing are top-down regulation and balanced loss confrontation. Top-down regulation is the ability to suppress processing of intrusive emotional information to pursue a stated goal. Top-down regulation may facilitate healthy grieving by allowing reprieve from intense loss related thinking. Balanced loss confrontation refers to the processing of the loss in a way that protects against emotional overload. Confrontation with the loss may assist in the process of reforming one's mental representations of the deceased. This study will test extrinsic and intrinsic measures of top-down regulation and balanced loss confrontation during acute grieving as predictors of CG development a year later. We will recruit a sample at high-risk for CG, the suicide-bereaved, in order to maximize the likeliness that a significant proportion of the sample develops CG. The findings produced by this study may advance the knowledge of how CG develops, assist in the identification of people at high-risk for developing CG and potentially form the basis for targeted interventions.

抽象的 大多数因失去亲人而悲伤的人都会经历一段时期的剧烈痛苦并专注于失去亲人 持续约6个月，称为急性悲伤。当以下经历发生时，就会出现复杂性悲伤（CG）： 严重的悲伤会持续到失去亲人后的 6 个月之后。关于损失的想法和感受（即悲伤处理） 急性悲伤期间发生的事件可能在健康悲伤中发挥作用，并防止 CG 发展。 识别有助于健康悲伤的悲伤处理的认知和情感机制 解决方案将增进对悲伤目标的了解，并协助制定针对悲伤的干预措施 复杂的悲伤。悲伤处理的两个核心组成部分是自上而下的调节和平衡损失 对抗。自上而下的调节是抑制侵入性情绪信息处理的能力 追求既定目标。自上而下的监管可以通过缓解严重的损失来促进健康的悲伤 相关思考。平衡损失对抗是指以防止损失的方式处理损失 情绪超负荷。面对损失可能有助于改变一个人的心理过程 死者的陈述。本研究将测试自上而下监管的外在和内在措施 急性悲伤期间的平衡失落对抗是一年后 CG 发展的预测因素。我们将招募 CG 高风险样本（即自杀者），以最大限度地提高很大比例的可能性 样本的CG。这项研究的结果可能会增进人们对 CG 如何 开发，协助识别患有 CG 的高风险人群，并可能为 有针对性的干预措施。

项目成果

Large-scale network dynamics in neural response to emotionally negative stimuli linked to serotonin 1A binding in major depressive disorder.

• DOI: 10.1038/s41380-020-0733-5
• 发表时间: 2021-06
• 期刊: Molecular psychiatry
• 影响因子: 11
• 作者: Schneck N;Tu T;Falcone HR;Miller JM;Zanderigo F;Sublette ME;Oquendo MA;Stanley B;Burke A;Ochsner K;Sajda P;John Mann J
• 通讯作者: John Mann J