Administrative Supplement for A Multilevel Physical Activity Intervention for South Asian Women and Girls

南亚妇女和女童多层次体育活动干预行政补充

• 批准号: 10771843
• 负责人: NAMRATHA R KANDULA
• 金额: $ 22.13万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10771843
• 关键词: Administrative Supplement; Adolescent; Asian Americans; Clinical Research; Clinical Trials; Communities; Daughter; Doctor of Philosophy; Enrollment; Ethnic Origin; Female; Female Adolescents; Funding; Future; Gender; Gender Role; Goals; Interview; Knowledge; Mentors; Modeling; Mothers; Outcome; Parents; Participant; Physical activity; Population Group; Population Heterogeneity; Prevention Research; Principal Investigator; Randomized, Controlled Trials; Research; Research Personnel; Research Subjects; Scientific Advances and Accomplishments; South Asian; Strategic Planning; Structure; United States National Institutes of Health; Woman; Women' s Health; cancer prevention; disorder prevention; disparity reduction; evidence base; exercise intervention; experience; girls; health disparity; health equity; implementation strategy; improved; lens; male; moderate-to-vigorous physical activity; recruit; sex

PROJECT SUMMARY Women and adolescent girls of South Asian background experience multilevel barriers to physical activity (PA). The South Asians Active Together (SAATH) trial (R01CA242520) is an ongoing randomized controlled trial that has enrolled 172 South Asian (SA) American mothers and adolescent daughters to evaluate the effects of a dyadic physical activity (PA) intervention on moderate to vigorous PA in SA women and girls. The goal of this administrative supplement to the SAATH trial is to conduct new research to identify and develop replicable strategies to overcome gender-specific barriers that South Asian women experience to clinical research participation. Our team has extensive experience with community-engaged recruitment of South Asian Americans in clinical research; however, SA women and girls remain underrepresented in PA and cancer prevention research despite persistent health disparities. Even with community-engaged recruitment approaches, there are strong differences between male and female participants regarding access to opportunities and multilevel influences on the decision to participate in clinical research. The research proposed in this supplement targets knowledge gaps about the influence and intersection of gender and ethnicity on implementation strategies to improve representation of SA women in clinical research. Specific Aims of this Administrative Supplement are to: 1) Identify how gendered roles, experiences, and identities influence access, participation, and inclusion as research subjects by performing and analyzing semi- structured interviews with SA mothers and daughters who did and did not participate in the SAATH trial (n=15 dyads); 2) Develop and evaluate replicable strategies using an intersectional lens and participatory action model for enhancing access and inclusion of SA women and adolescent girls in PA and cancer prevention research. This administrative supplement is led by Principal Investigator (PI) Namratha Kandula, MD, MPH and includes an early stage investigator, Milkie Vu, PhD who will be mentored by the Dr. Kandula to accomplish the scientific goals of the parent study and supplement. This administrative supplement will address Objective 1.2, Objective 2.4, and Objective 3.1of the Trans-NIH Strategic Plan for Women's Health Research, which seek to investigate the influence of sex and gender on disease prevention, presentation, management, and outcomes, improve the recruitment and retention of women underrepresented in clinical research, and disseminate and implement evidence-based strategies to improve women's health. Results new commitment from this supplement will provide knowledge about the intersection of gender and ethnicity to inform replicable strategies to improve of SA women and adolescents girls for future PA and cancer prevention studies.

项目摘要 南亚背景的妇女和青少年女孩经历了体育锻炼的多层次障碍（PA）。 南亚人一起活跃（SAATH）试验（R01CA242520）是一项正在进行的随机对照试验 已经招募了172个南亚（SA）美国母亲和青少年女儿，以评估 SA妇女和女孩对中度至有力的PA的二元运动（PA）干预。目标的目标 SAATH试验的行政补充是进行新的研究以识别和开发可复制的 克服南亚妇女经历临床研究的性别特异性障碍的策略 参与。我们的团队在社区参与南亚的招聘方面有丰富的经验 美国人在临床研究中；但是，在PA和癌症中，SA妇女和女孩的人数不足 尽管健康差异持续存在，但预防研究。即使有社区参与的招聘 方法，男性和女性参与者之间在访问方面存在很大差异 机会和多层次影响参与临床研究的决定。研究 在此补充中提出的目标是有关性别影响和交集的知识差距 实施策略的种族，以改善SA妇女在临床研究中的代表性。 这种行政补充的具体目的是：1）确定性别角色，经验和如何 身份通过执行和分析半 与SA母亲和女儿的结构化访谈，他们没有参加过，也没有参加Saath审判（n = 15 二元）; 2）使用交叉镜头和参与式行动制定和评估可复制的策略 在PA和预防癌症中增强SA妇女和青少年女孩的访问和纳入模型 研究。此行政补充由主要研究员（PI）Namratha Kandula，MD，MPH和 包括一名早期舞台调查员，米尔米·VU，博士，他将得到坎多拉博士的指导 父母研究和补充的科学目标。这种行政补充将解决目标1.2， 目标2.4和目标3.1的妇女健康研究的Trans-NIH战略计划，该计划试图 研究性别和性别对疾病预防，表现，管理和结果的影响， 改善在临床研究中代表不足的妇女的招聘和保留，并进行传播和 实施基于证据的策略来改善妇女健康。结果 新的 承诺 该补充剂将提供 关于性别和种族交集的知识，以告知可复制策略以改善 SA妇女和青少年女孩的未来PA和癌症预防研究。