Mentoring in community engaged implementation research to reduce cardiovascular disparities

指导社区参与实施研究以减少心血管差异

基本信息

批准号：
10455407
负责人：
NAMRATHA R KANDULA
金额：
$ 12.15万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10455407
关键词：
Address Adolescent Adult Affect American Heart Association Americas Asian Americans Atherosclerosis Blood Pressure Cardiovascular Diseases Cardiovascular system Clinical Clinical Research Communities Daughter Diabetes Mellitus Diet East Asian Education Effectiveness Effectiveness of Interventions Enrollment Environment Ethnic group Evaluation Evidence based intervention Family Female Adolescents Funding Future Gender Glucose Goals Health Health Educators Health behavior Heart Diseases High Prevalence Hispanic Populations Hypertension Immigrant Immigration Income Individual Infrastructure Intervention Intervention Trial Knowledge Language Leadership Link Lipids Measures Mediator of activation protein Medicine Mentors Mentorship Methods Midcareer Investigator Award in Patient-Oriented Research Minority Modeling Mothers National Heart, Lung, and Blood Institute Neighborhood Health Center Neighborhoods Not Hispanic or Latino Outcome Participant Physical activity Population Prevention strategy Preventive Medicine Public Health Research Research Methodology Research Personnel Resources Risk Factors Scholarship Science South Asian Testing Time Training United States United States National Institutes of Health Universities Vulnerable Populations Weight Woman Work base cardiovascular disorder prevention cardiovascular disorder risk cardiovascular health community based participatory research community burden community engaged research community partnership community setting contextual factors disease disparity effectiveness evaluation effectiveness outcome epidemiology study evidence base exercise intervention future implementation health care availability health disparity health disparity populations health equity healthy lifestyle high risk hybrid type 1 design implementation evaluation implementation outcomes implementation research implementation science implementation strategy improved innovation lifestyle intervention medical schools men mid-career faculty mortality next generation physical inactivity practice setting racial and ethnic research to practice skills social social determinants social health determinants social structure stakeholder perspectives student mentoring treatment research

项目摘要

PROJECT SUMMARY This is a proposal for a K24 Midcareer Investigator Award in Patient-Oriented Research (POR) for Namratha Kandula, MD, MPH of Northwestern University Feinberg School of Medicine. Dr. Kandula is Associate Professor of Medicine and Preventive Medicine and co-Director of the Center for Community Health. Dr. Kandula's scholarship is focused on understanding the social and cultural determinants of cardiovascular disease (CVD) disparities in South Asian Americans and implementing evidence-based interventions (EBIs) using community-based participatory research (CBPR) methods. South Asian Americans, the majority of whom are immigrants, are disproportionately affected by CVD compared to non-Hispanic whites and other Asian Americans. While there is ample evidence that intensive diet and physical activity interventions improve CVD risk factors in adults, these EBIs have limited reach in South Asian and other vulnerable populations because most EBIs were developed in narrow clinical populations, lack cultural salience, do not account for multilevel social determinants of health, and are difficult to implement in new settings. Dr. Kandula has expertise in epidemiologic studies and community-based lifestyle intervention trials and has been actively mentoring students and junior investigators on health disparities and community engaged research. The objective of this K24 application is to promote science and mentorship in community engaged implementation research to optimally deliver and sustain EBIs focused on populations with a high burden of health disparities. Support from the K24 will provide Dr. Kandula with protected time to: 1) Devote more time to mentoring a diverse group of young investigators in community engaged implementation research; 2) Improve her implementation science research and mentoring skills through mentor training and guidance from senior mentors; 3) Extend her currently funded work to fill critical gaps in the science of delivering and sustaining EBIs for vulnerable populations; and 4) Assume leadership in new multisector, collaborative research on how to optimally deliver EBIs to eliminate health disparities. The current K24 proposal builds upon the scientific premise and extends the research and mentorship of the PI in the context of her two NIH-funded, community engaged lifestyle intervention trials to reduce CVD disparities in South Asian adults and adolescents (SAHELI and SAATH trials). The PI and her mentees will use mixed methods to: 1) Investigate social and structural determinants that contributed to differences in implementation outcomes of EBIs in the SAHELI and SAATH trials; 2) Evaluate sustainability of the EBIs implemented in the SAHELI and SAATH trials; and 3) Understand stakeholder perspectives on which implementation outcomes and evaluation strategies are most meaningful and feasible when implementing EBIs for CVD prevention in health disparity populations. Conduct of the proposed Aims will accelerate science and mentorship in building sustainable community partnerships and models to optimally deliver EBIs that improve the health of vulnerable populations and advance health equity.

项目摘要这是namratha的K24中级护理研究员奖（POR）的提案坎杜拉（Kandula），医学博士，西北大学费恩伯格医学院的MPH。 Kandula博士是同事医学和预防医学教授以及社区卫生中心的联合主任。 Kandula博士的奖学金专注于了解心血管的社会和文化决定因素南亚美国人的疾病（CVD）差异并实施循证干预措施（EBIS）使用基于社区的参与性研究（CBPR）方法。南亚美国人，大多数是移民，与非西班牙裔白人和其他亚洲人相比，受CVD的影响不成比例美国人。尽管有足够的证据表明强化饮食和体育锻炼干预措施可改善CVD 成年人的危险因素，这些EBI在南亚和其他脆弱人群中的影响力有限，因为大多数EBI是在狭窄的临床人群中开发的，缺乏文化显着性，不考虑多层次卫生的社会决定因素，在新环境中难以实施。 Kandula博士有专业知识流行病学研究和基于社区的生活方式干预试验，并一直在积极指导学生和初级调查人员关于健康差异和社区参与研究的研究人员。这个目的 K24的应用是为了促进社区参与实施研究中的科学和指导最佳地交付和维持EBI，专注于具有较高健康差异负担的人群。支持来自K24将为Kandula博士提供受保护的时间：1）花更多的时间指导一个多样化的群体社区参与实施研究的年轻调查员； 2）改善她的实施科学通过高级导师的导师培训和指导来研究和指导技能； 3）延长她目前有资助的工作，以填补为弱势群体提供和维持EBIS科学的关键空白人口； 4）在新的多部门领导 EBI消除健康差异。当前的K24提案建立在科学前提之上，并扩展 PI的研究和指导是她两个由NIH资助的，社区参与的生活方式的背景干预试验以减少南亚成年人和青少年的CVD差异（Saheli和Saath 试验）。 PI和她的受训者将使用混合方法来：1）调查社会和结构决定因素这导致了Saheli和Saath试验中EBI的实施成果的差异； 2）评估Saheli和Saath试验中实施的EBI的可持续性； 3）理解利益相关者的观点对哪些实施结果和评估策略是最有意义的并且在实施EBIS在健康差异人群中预防CVD时可行。行为拟议的目标将加速科学和指导，以建立可持续的社区伙伴关系和最佳地提供EBI的模型，以改善脆弱人群的健康并提高健康公平。