An Analysis of Psychosocial Risk and Protective Factors: Accelerated Cognitive Aging and Mild Traumatic Brain Injury (MTBI) Among Retired NFL & Former NCAA Football Players

心理社会风险和保护因素分析：退役 NFL 加速认知老化和轻度创伤性脑损伤 (MTBI)

• 批准号: 9754726
• 负责人: Robert W. Turner
• 金额: $ 12.25万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9754726
• 关键词: Address; Adult; Age; Aging; Alzheimer' s Disease; Applications Grants; Area; Attitude; Awareness; Brain Concussion; Brain Injuries; Brain imaging; Cessation of life; Characteristics; Cognition; Cognitive; Cognitive aging; Collaborations; Control Groups; Data; Demographic Factors; Disease; Elderly; Emergency department visit; Ethnography; Exercise; Exhibits; Exposure to; Focus Groups; Freedom; Frequencies; Gender; Goals; Health; Health Campaign; Health Care Costs; Health Status; Healthcare; Hospitalization; Individual; Injury; Instruction; Interview; Knowledge; Lead; Life; Life Cycle Stages; Manufactured football; Measures; Mediating; Medical; Medical Sociology; Memory impairment; Mental Depression; Mental Health; Mentored Research Scientist Development Award; Mentors; Methods; Modeling; National Institute on Aging; Neurocognitive; Neurodegenerative Disorders; Pain; Pattern; Personal Satisfaction; Population; Portraits; Postdoctoral Fellow; Process; Psychosocial Assessment and Care; Psychosocial Factor; Psychosocial Stress; Public Health; Race; Reading; Recording of previous events; Reporting; Research; Research Personnel; Research Project Grants; Research Technics; Risk; Risk Factors; Series; Severities; Surveys; Testing; Training; Training Activity; Training Support; United States; Universities; Variant; Veterans; Work; age related; biobehavior; biopsychosocial; brain health; career; career development; chronic depression; chronic pain; chronic traumatic encephalopathy; cognitive function; cognitive process; cohort; college; coping; cost; design; ethnographic method; evidence base; executive function; experience; fitness; health care availability; health care service utilization; health difference; health disparity; improved; indexing; individual variation; innovation; insight; male; men; mild cognitive impairment; mild traumatic brain injury; neuropsychiatry; operation; perceived stress; physical conditioning; protective factors; psychologic; psychosocial; racial and ethnic; sociodemographics

Project Summary/Abstract: Robert W. Turner II is a Research Associate in the Center on Biobehavioral Health Disparities Research at Duke University. He has training in medical sociology, ethnographic methods, and health disparities research as well as a strong commitment to improving the mental health of adult males. His previous and current work has exposed him to theoretical perspectives and empirical approaches pertinent to health disparity and aging research among men. The current proposal is for a five year Mentored Research Scientist Development Award (K01) from the National Institute on Aging for training and support that address gaps in his knowledge of biobehavioral factors underlying mild traumatic brain injury mTBI and accelerated cognitive aging. In collaboration with his mentoring team (Drs. Tim Strauman, Keith Whitfield, and Toni Antonucci) he has developed a comprehensive training and research plan that will both fill in these knowledge gaps and prepare him for an independent research career. The overarching goal of his K01 is to become an expert on the interrelationships between multiple measures of psychosocial and neurocognitive factors associated with accelerated cognitive aging, and serve as bridge for him to establish an independent investigator career in conducting biobehavioral health disparities research in aging adult male populations. To accomplish this goal, he proposes four career development activities and three research aims that combines instruction with established scholars in survey research techniques; formal coursework; participation in ongoing seminars at Duke University; one-to-one directed readings with mentors; and finally, conduction of a “proof of concept study” from start to finish. Preliminary data will be collected with using a mixed-method design that consists of a survey, focus groups, and in-depth interviews. The two research aims will enable him to integrate and apply the knowledge that he will gain through the proposed training activities by creating a more robust overall portrait of psychosocial protective and risk factors that may impact the long-term consequences of mTBI among men than previously possible. The approach used in this project will address; a) male vulnerabilities in predicting the impact of psychosocial factors on accelerated cognitive aging and b) how understandings of masculinity develop across and within groups in relationship to pain, injury, and brain health. This project will continue to build on insights he has gained through his examination of data from the Study of Retired NFL Players. By completing these aims, he will test important hypotheses and make a substantial contribution to the evidence base by describing the process of cognitive accelerated aging resulting from mTBI. This proposal is relevant to public health because it will explore innovative approaches to address functional, cognitive, and psychosocial vulnerabilities in concussed men, and may ultimately reduce the risk of Chronic Traumatic Encephalopathy (CTE), and Alzheimer's disease resulting from concussions. It will also inform an R-series grant proposal to study accelerated cognitive aging and brain imaging that Dr. Turner plans to submit in year 4 of the project.

项目摘要/摘要：罗伯特·W·特纳二世 (Robert W. Turner II) 是该中心的研究员 他在杜克大学进行生物行为健康差异研究，接受过医学社会学培训。 民族志方法和健康差异研究以及对改善 他之前和当前的工作使他接触到了成年男性的心理健康理论。 与男性健康差异和老龄化研究相关的观点和实证方法。 目前的提案是颁发五年期指导研究科学家发展奖（K01） 国家老龄化研究所提供培训和支持，以解决他在生物行为知识方面的差距 轻度创伤性脑损伤 mTBI 和加速认知老化的潜在因素。 他与他的指导团队（Tim Strauman 博士、Keith Whitfield 和 Toni Antonucci）一起开发了一种 全面的培训和研究计划，既可以填补这些知识空白，又可以让他做好准备 他的 K01 的首要目标是成为该领域的专家。 相关心理社会和神经认知因素的多种测量之间的相互关系 加速认知老化，并为他建立独立研究者提供桥梁 从事老年男性群体生物行为健康差异研究。 为了实现这一目标，他提出了四项职业发展活动和三个研究目标： 教学与调查研究技术方面的知名学者相结合； 参加杜克大学正在进行的研讨会；与导师进行一对一的定向阅读； 最后，将收集从头到尾的“概念验证研究”。 采用混合方法设计，包括调查、焦点小组和深度访谈。 两个研究目标将使他能够整合和应用他通过研究获得的知识 通过创建更健全的社会心理保护和风险总体描述来提议培训活动 可能影响男性 mTBI 长期后果的因素比以前可能的多。 该项目使用的方法将解决男性在预测影响方面的脆弱性； 加速认知老化的心理社会因素以及 b) 对男性气质的理解如何发展 该项目将继续在群体之间和群体内开展与疼痛、伤害和大脑健康相关的研究。 建立在他通过检查退役 NFL 球员研究数据获得的见解的基础上。 通过完成这些目标，他将检验重要的假设，并为研究做出重大贡献。 通过描述 mTBI 导致的认知加速衰老过程的证据基础。 该提案与公共卫生相关，因为它将探索创新方法来解决功能性、 脑震荡男性的认知和心理脆弱性，并可能最终降低患脑震荡的风险 慢性创伤性脑病（CTE）和脑震荡引起的阿尔茨海默病。 还告知 R 系列拨款提案，以研究加速认知老化和大脑成像，博士。 特纳计划在该项目的第四年提交。