UW Center on Outcomes Research in Rehabilitation(RMI)

华盛顿大学康复结果研究中心 (RMI)

• 批准号: 7489266
• 负责人: DAGMAR AMTMANN
• 金额: $ 81.64万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-28 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7489266
• 关键词: Adopted; Adult; Age; Child; Chronic Disease; Clinical; Clinical Research; Cross-Sectional Studies; Data; Diagnosis; Disabled Children; Ensure; Fatigue; Gender; Individual; Longitudinal Studies; Measurement; Measures; Medical; Mental Depression; Methods; Modeling; Multiple Sclerosis; Outcome; Outcome Measure; Outcomes Research; Pain; Pain Measurement; Pain management; Participant; Pattern; Population Study; Range; Rehabilitation therapy; Research; Research Personnel; Research Project Grants; Spinal cord injury; Subgroup; Support System; Symptoms; System; Testing; Time; Universities; Washington; base; concept; design; disability; improved; instrument; prospective; response; theories; tool; young adult

DESCRIPTION (provided by applicant): The University of Washington Center on Outcomes Research in Rehabilitation (UWCORR) has the broad, long-term objectives of providin.q clinical researchers with better tools or methods to measure patientreported outcomes (PRO) in children and adults with chronic disease and disability by using modern measurement theory and other sophisticated approaches to improve instruments and approaches used to measure pain and fatigue, and understanding of associations between pain and fatigue, and their impact on important outcome variables. The independent research project proposes to conduct two studies. Study 1 is a cross-sectional study of pain and fatigue and their impact on important outcome measures (participation, depression, and disability level) in 1,200 adults and children. Study 2 is a prospective, longitudinal study with 300 adults and children assessed on the set of core measures over six, six month intervals. We will use item response theory modeling framework and other appropriate methods to refine the items and scales, and to propose a set of improved core measures/items for assessment of pain and fatigue in adults and youth with disabilities. We will also test the associations between pain and fatigue, and their relationship to depression, level of disability, and participation in activities using both cross-sectional and longitudinal data. Better understanding of the association of pain and fatigue with important outcomes will allow us to select those items/scales that are most strongly associated with the changes in the outcome variables. Data from Study 2 (longitudinal) will be used to identify reliable subgroups within and across different disability groups characterized by trajectories with a certain pattern of pain and fatigue symptoms. This will inform the final selection of items/scales most relevant to each of the subgroups identified as well as research on treatment and management of pain and fatigue. We propose that PROMISE adopt the following two concepts as Network Projects: (1) develop a psychometrically valid, dynamic system to measure participation in activities for individuals with a broad range of disabilities; utilize the universal design principles to ensure that item banks, CAT system, and supporting materials are fully accessible to researchers, participants, and other constituents, including those with disabilities.

描述（由申请人提供）：华盛顿大学康复结果研究中心 (UWCORR) 拥有 providin.q 临床研究人员广泛、长期的目标，拥有更好的工具或方法来衡量儿童和成人的患者报告结果 (PRO)通过使用现代测量理论和其他复杂的方法来改进用于测量疼痛和疲劳的仪器和方法，并了解疼痛和疲劳之间的关联及其对重要结果变量的影响，以应对慢性疾病和残疾。该独立研究项目拟进行两项研究。研究 1 是一项针对 1,200 名成人和儿童的疼痛和疲劳及其对重要结果指标（参与度、抑郁度和残疾程度）影响的横断面研究。研究 2 是一项前瞻性纵向研究，对 300 名成人和儿童进行了为期六六个月的核心指标评估。我们将使用项目反应理论建模框架和其他适当的方法来完善项目和量表，并提出一套改进的核心措施/项目来评估残疾成人和青少年的疼痛和疲劳。我们还将使用横截面和纵向数据来测试疼痛和疲劳之间的关联，以及它们与抑郁、残疾程度和活动参与的关系。更好地理解疼痛和疲劳与重要结果的关联将使我们能够选择与结果变量变化最密切相关的项目/量表。研究 2（纵向）的数据将用于识别不同残疾群体内部和之间的可靠亚组，这些亚组的特征是具有某种疼痛和疲劳症状模式的轨迹。这将为与所确定的每个亚组最相关的项目/量表的最终选择以及疼痛和疲劳的治疗和管理的研究提供信息。我们建议 PROMISE 采用以下两个概念作为网络项目：（1）开发一个心理测量上有效的动态系统来衡量各种残疾人的活动参与情况；利用通用设计原则，确保研究人员、参与者和其他成员（包括残疾人）能够完全访问项目库、CAT 系统和支持材料。

项目成果

Measuring pain in the context of homelessness.

• DOI: 10.1007/s11136-009-9507-x
• 发表时间: 2009-09
• 期刊: QUALITY OF LIFE RESEARCH
• 影响因子: 3.5
• 作者: Matter, Rebecca;Kline, Susan;Cook, Karon F.;Amtmann, Dagmar
• 通讯作者: Amtmann, Dagmar

The 7-item generalized anxiety disorder scale as a tool for measuring generalized anxiety in multiple sclerosis.

• DOI: 10.7224/1537-2073.2014-008
• 发表时间: 2015-03-01
• 期刊: International journal of MS care
• 作者: Terrill, Alexandra L;Hartoonian, Narineh;Alschuler, Kevin
• 通讯作者: Alschuler, Kevin

Beyond fatigue: Assessing variables associated with sleep problems and use of sleep medications in multiple sclerosis.

• DOI: 10.2147/clep.s10425
• 发表时间: 2010-05-01
• 期刊: Clinical epidemiology
• 影响因子: 3.9
• 作者: Bamer AM;Johnson KL;Amtmann DA;Kraft GH
• 通讯作者: Kraft GH

Testing the measurement invariance of the University of Washington Self-Efficacy Scale short form across four diagnostic subgroups.

• DOI: 10.1007/s11136-016-1300-z
• 发表时间: 2016-10
• 期刊: QUALITY OF LIFE RESEARCH
• 影响因子: 3.5
• 作者: Chung, Hyewon;Kim, Jiseon;Park, Ryoungsun;Bamer, Alyssa M.;Bocell, Fraser D.;Amtmann, Dagmar
• 通讯作者: Amtmann, Dagmar

Pain affects depression through anxiety, fatigue, and sleep in multiple sclerosis.

• DOI: 10.1037/rep0000027
• 发表时间: 2015-02
• 期刊: REHABILITATION PSYCHOLOGY
• 影响因子: 2.7
• 作者: Amtmann, Dagmar;Askew, Robert L.;Kim, Jiseon;Chung, Hyewon;Ehde, Dawn M.;Bombardier, Charles H.;Kraft, George H.;Jones, Salene M.;Johnson, Kurt L.
• 通讯作者: Johnson, Kurt L.