Informing alcohol policy: The impact of evidence-based alcohol warnings on consumption

告知酒精政策：基于证据的酒精警告对消费的影响

• 批准号: 10565120
• 负责人: Anna H Grummon
• 金额: $ 57.23万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-20 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10565120
• 关键词: 2 arm randomized control trial; Accounting; Address; Adopted; Adult; Age; Alcohol consumption; Alcohols; American; Authorization documentation; Back; Behavior; Cause of Death; Cessation of life; Communication; Consumption; Data; Development; Disease; Education; Effectiveness; Elements; Ensure; Equation; Evidence based practice; Exposure to; Federal Government; Gender; Guidelines; Health; Home; Injury; Interview; Label; Laboratories; Legal; Measures; Mediation; Mediator; Meta-Analysis; Methods; Modeling; Participant; Policies; Policy Making; Probability Samples; Product Labeling; Protocols documentation; Randomized; Recommendation; Research; Risk; Rotation; Sampling; Side; Smoking; Speed; Subgroup; Surveys; Testing; Time; United States; Update; Visit; Woman; Work; alcohol risk; arm; authority; behavior influence; binge drinking; cancer type; design; diaries; disability; drinking; evidence base; experimental analysis; experimental study; health warning; hypertensive heart disease; innovation; insight; men; primary outcome; psychologic; public policy on alcohol; randomized trial; recruit; secondary outcome; warning label

PROJECT ABSTRACT Nearly 1 in 3 American adults exceed the recommended limit for alcohol consumption, increasing their risk of health problems including hypertensive heart disease, injuries, and several types of cancer. Most adults are not aware of the harms of alcohol consumption. Evidence-based warnings on alcohol containers that are displayed prominently on the front of the package, include pictorial elements such as icons, and rotate their content over time could inform consumers and discourage unhealthy alcohol consumption. The overarching objective of this proposal is to evaluate the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 1, we will use existing research and expert review to optimize warning statements describing the health harms of alcohol consumption. We will then test an array of evidence-based warnings in a randomized experiment with a nationally representative sample of 910 adult regular alcohol consumers. The main product of Aim 1 will be the selection of 4 evidence-based warnings that participants endorse as effective for use in Aim 2. In Aim 2, we will evaluate the impact of these evidence-based alcohol warnings on alcohol consumption in a longitudinal RCT. We will recruit 786 adult regular alcohol consumers. Participants will be randomly assigned to a warnings arm or a control arm. In a 4-week study, participants in the warnings arm will receive the 4 unique evidence-based warnings affixed to their alcohol containers, allocated in random order. In the control arm, no new labels will be applied. We will assess whether the evidence-based alcohol warnings reduce number of drinks consumed (measured using daily diaries) and examine whether this effect varies by baseline alcohol use, gender, age, and education. We will also evaluate how warnings influence potential psychological mediators (measured in weekly surveys). The final product of Aim 2 will be an estimate of the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 3, we will validate a model of how alcohol warnings influence alcohol consumption. We will conduct in-depth interviews with participants in the warnings arm of Aim 2’s RCT to elicit insights about the mechanisms through which the trial warnings influenced their behavior. Then, we will apply mediation analyses to the longitudinal daily diary and survey data collected in Aim 2’s RCT to identify mediators of the impact of the trial warnings on alcohol consumption. The final product of Aim 3 will be a model of how evidence-based alcohol warnings influence alcohol consumption. This research is responsive to NOT-AA-21-028 by conducting causal analyses of an alcohol-reduction policy and advancing methods by implementing an innovative RCT with naturalistic exposure to warnings. Our findings will create an evidence base to inform development of effective alcohol warnings as well as other communication campaigns. Ultimately, new evidence-based alcohol warnings could reduce unhealthy alcohol consumption and address rising rates of alcohol-attributable disease and death in the US and globally.

项目摘要 近三分之一的美国成年人超过了饮酒的建议限制，增加了他们的风险 健康问题，包括高血压心脏病，损伤和几种类型的癌症。大多数成年人是 不知道饮酒的危害。对酒精容器的循证警告 在包装的正面上突出显示，包括图标等图形元素，并旋转它们 随着时间的流逝，内容可以为消费者提供信息，并阻止不健康的酒精消耗。总体 该建议的目的是评估循证酒精警告对酒精的影响 消耗。在AIM 1中，我们将使用现有的研究和专家审查来优化警告声明 描述饮酒的健康危害。然后，我们将测试一系列基于证据的警告 由910名成年人常规饮酒者的全国代表性样本进行的随机实验。 AIM 1的主要产品将选择4个基于证据的警告，参与者认可有效 在AIM 2中使用。在AIM 2中，我们将评估这些基于证据的酒精警告对酒精的影响 纵向RCT的消费。我们将招募786名成人常规酒精消费者。参与者会 随机分配给警告臂或控制臂。在一项为期4周的研究中，警告部门的参与者将 接收4个独特的基于证据的警告，这些警告固定在其酒精容器上，以随机顺序分配。在 控制臂，不会应用新标签。我们将评估是否基于证据的酒精警告 减少消耗的饮料数量（使用每日日记测量），并检查这种效果是否有所不同 基线饮酒，性别，年龄和教育。我们还将评估警告如何影响潜力 心理调解人（在每周调查中衡量）。 AIM 2的最终产品将是对 在AIM 3中，我们将验证一个模型 酒精警告会影响饮酒。我们将对参与者进行深入的访谈 AIM 2的RCT警告部门，以引起有关审判警告的机制的见解 影响了他们的行为。然后，我们将对纵向日记和调查数据进行调解分析 收集在AIM 2的RCT中，以确定试验警告对饮酒的影响的调解人。 AIM 3的最终产品将是一个模型，表明循证酒精警告如何影响酒精消耗。 这项研究通过进行饮酒的因果分析来响应非AA-21-028 政策和推进方法通过实施具有自然主义警告的创新RCT。 我们的发现将创建一个证据基础，以告知开发有效的酒精警告以及其他 沟通运动。最终，新的基于证据的酒精警告可能会减少不健康的酒精 在美国和全球的饮酒疾病和死亡的消费率和解决率的增加。