Informing alcohol policy: The impact of evidence-based alcohol warnings on consumption

告知酒精政策：基于证据的酒精警告对消费的影响

• 批准号: 10565120
• 负责人: Anna H Grummon
• 金额: $ 57.23万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-20 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10565120
• 关键词: 2 arm randomized control trial; Accounting; Address; Adopted; Adult; Age; Alcohol consumption; Alcohols; American; Authorization documentation; Back; Behavior; Cause of Death; Cessation of life; Communication; Consumption; Data; Development; Disease; Education; Effectiveness; Elements; Ensure; Equation; Evidence based practice; Exposure to; Federal Government; Gender; Guidelines; Health; Home; Injury; Interview; Label; Laboratories; Legal; Measures; Mediation; Mediator; Meta-Analysis; Methods; Modeling; Participant; Policies; Policy Making; Probability Samples; Product Labeling; Protocols documentation; Randomized; Recommendation; Research; Risk; Rotation; Sampling; Side; Smoking; Speed; Subgroup; Surveys; Testing; Time; United States; Update; Visit; Woman; Work; alcohol risk; arm; authority; behavior influence; binge drinking; cancer type; design; diaries; disability; drinking; evidence base; experimental analysis; experimental study; health warning; hypertensive heart disease; innovation; insight; men; primary outcome; psychologic; public policy on alcohol; randomized trial; recruit; secondary outcome; warning label

PROJECT ABSTRACT Nearly 1 in 3 American adults exceed the recommended limit for alcohol consumption, increasing their risk of health problems including hypertensive heart disease, injuries, and several types of cancer. Most adults are not aware of the harms of alcohol consumption. Evidence-based warnings on alcohol containers that are displayed prominently on the front of the package, include pictorial elements such as icons, and rotate their content over time could inform consumers and discourage unhealthy alcohol consumption. The overarching objective of this proposal is to evaluate the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 1, we will use existing research and expert review to optimize warning statements describing the health harms of alcohol consumption. We will then test an array of evidence-based warnings in a randomized experiment with a nationally representative sample of 910 adult regular alcohol consumers. The main product of Aim 1 will be the selection of 4 evidence-based warnings that participants endorse as effective for use in Aim 2. In Aim 2, we will evaluate the impact of these evidence-based alcohol warnings on alcohol consumption in a longitudinal RCT. We will recruit 786 adult regular alcohol consumers. Participants will be randomly assigned to a warnings arm or a control arm. In a 4-week study, participants in the warnings arm will receive the 4 unique evidence-based warnings affixed to their alcohol containers, allocated in random order. In the control arm, no new labels will be applied. We will assess whether the evidence-based alcohol warnings reduce number of drinks consumed (measured using daily diaries) and examine whether this effect varies by baseline alcohol use, gender, age, and education. We will also evaluate how warnings influence potential psychological mediators (measured in weekly surveys). The final product of Aim 2 will be an estimate of the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 3, we will validate a model of how alcohol warnings influence alcohol consumption. We will conduct in-depth interviews with participants in the warnings arm of Aim 2’s RCT to elicit insights about the mechanisms through which the trial warnings influenced their behavior. Then, we will apply mediation analyses to the longitudinal daily diary and survey data collected in Aim 2’s RCT to identify mediators of the impact of the trial warnings on alcohol consumption. The final product of Aim 3 will be a model of how evidence-based alcohol warnings influence alcohol consumption. This research is responsive to NOT-AA-21-028 by conducting causal analyses of an alcohol-reduction policy and advancing methods by implementing an innovative RCT with naturalistic exposure to warnings. Our findings will create an evidence base to inform development of effective alcohol warnings as well as other communication campaigns. Ultimately, new evidence-based alcohol warnings could reduce unhealthy alcohol consumption and address rising rates of alcohol-attributable disease and death in the US and globally.

项目摘要 近三分之一的美国成年人超过了建议的饮酒限量，这增加了他们的风险 大多数成年人都患有高血压、心脏病、损伤和多种癌症等健康问题。 不了解饮酒容器上的基于证据的警告。 显示在包装正面的显着位置，包括图标等图形元素，并旋转它们 随着时间的推移，内容可以告知消费者并阻止不健康的饮酒。 该提案的目的是评估基于证据的酒精警告对酒精的影响 在目标 1 中，我们将利用现有研究和专家评审来优化警告声明。 然后，我们将测试一系列基于证据的警告。 一项随机实验，选取了具有全国代表性的 910 名成年经常饮酒者作为样本。 目标 1 的主要成果将是选择 4 个基于证据的警告，参与者认可这些警告是有效的 用于目标 2。在目标 2 中，我们将评估这些基于证据的酒精警告对酒精的影响 我们将招募 786 名成年普通酒精消费者作为参与者。 在为期 4 周的研究中，警告组的参与者将被随机分配到警告组或对照组。 收到贴在酒精容器上的 4 个独特的基于证据的警告，这些警告按随机顺序分配。 控制臂，我们将评估是否有基于证据的酒精警告。 减少饮酒量（使用每日日记测量）并检查这种效果是否因 我们还将评估警告如何影响潜在的饮酒情况。 心理中介（在每周调查中测量）。目标 2 的最终结果将是对 基于证据的酒精警告对饮酒的影响 在目标 3 中，我们将验证一个模型。 酒精警告会影响饮酒量。 Aim 2 的 RCT 的警告部分旨在深入了解试验警告的机制 然后，我们将对纵向日记和调查数据应用中介分析。 在目标 2 的随机对照试验中收集，以确定试验警告对饮酒影响的中介因素。 Aim 3 的最终产品将是基于证据的酒精警告如何影响酒精消费的模型。 本研究通过对酒精减少分析进行因果分析来响应 NOT-AA-21-028 通过实施具有自然警告暴露的创新随机对照试验来制定政策和推进方法。 我们的研究结果将为制定有效的酒精警告以及其他措施提供依据 最终，新的基于证据的酒精警告可以减少不健康的酒精。 消费并解决美国和全球酒精引起的疾病和死亡率上升的问题。