Enhancing Duke University's Animal Resources

增强杜克大学的动物资源

• 批准号: 7246256
• 负责人: JOHN N. NORTON
• 金额: $ 69.99万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7246256
• 关键词: Academic Medical Centers; Administrator; Animals; Appendix; Arts; Biomedical Research; Consult; Derivation procedure; Educational process of instructing; Embryo; Equipment; Excision; Facility Construction Funding Category; Faculty; Floor; Funding; Future; Genome; Goals; Grant; Health Status; Housing; IACUC; Individual; Intellectual Property; Laboratories; Lead; Letters; Medical; Modernization; Mus; National Center for Research Resources; Osmosis; Outcome; Population; Quality of Care; Range; Research; Research Personnel; Resources; Rodent; Science; Source; Stainless Steel; Standards of Weights and Measures; Structure; System; United States Public Health Service; Universities; Water; Water Purification; animal care; animal facility; animal resource; foot; improved; member; pathogen; programs

DESCRIPTION (provided by applicant): The Division of Laboratory Animal Resources continues its efforts to upgrade and improve the quality of Duke University's animal resources program. The needs of our program support the intellectual property of 400 faculty who use more than 25 species and bring $403 million of direct funds for animal-related research to the Universtity. Duke has invested significant resources over the last few years to build and equip the state of the art Genome Sciences Research Building II (GSRB II) with capacity for 19,000 mouse cages, and currently has under construction Medical Sciences Research Building II (MSRB II) which includes 10,800 net square feet of new animal space. The momentum engendered by GSRB II, MSRB II and a recently completed Animal Resources Improvement Grant is being applied to older campus animal facilities in a continuing effort to bring(them up to appropriate standards, enhance their capacities and improve the health status of animals campus-wide. Duke proposes utilizing these NCRR funds to augment current animal resource improvement initiatives underway. The specific aims of this proposal are to: 1) extend the existing Central Vivarium reverse osmosis water purification system and stainless steel room distribution systems to the remaining 27 animal rooms currently with no or antiquated watering and; 2) renovate the Medical Sciences Research Building I (MSRB I) in accordance with a recently-completed animal facilities master plan to serve as a campus-wide rodent rederivation core. Proposed MSRB I renovations include removal of existing animal room isolation cubicles, installation of a sterilizer, resurfacing of all floors, acquisition of ventilated rodent cage racks as well as needed rederivation equipment. Each of these aims will also help increase the housing capacity of both facilities, helping meet the need of ever increasing animal populations. The equipment and improvements described in this application are needed to continue the modernization of our facilities, provide the highest quality of care to the animals and sustain the research efforts of the faculty.

描述（由申请人提供）： 实验动物资源部继续努力升级和提高杜克大学动物资源项目的质量。我们的项目需要支持 400 名教员的知识产权，他们使用超过 25 个物种，并为大学带来 4.03 亿美元的直接资金用于动物相关研究。杜克大学在过去几年中投入了大量资源来建造和装备最先进的基因组科学研究大楼 II (GSRB II)，可容纳 19,000 个小鼠笼子，目前正在建设的医学科学研究大楼 II (MSRB II)包括 10,800 净平方英尺的新动物空间。 GSRB II、MSRB II 和最近完成的动物资源改善补助金所产生的动力正在应用于旧的校园动物设施，不断努力使它们达到适当的标准，增强其能力并改善校园动物的健康状况-杜克大学建议利用这些 NCRR 资金来加强当前正在进行的动物资源改善计划。 该提案的具体目标是： 1) 将现有的 Central Vivarium 反渗透水净化系统和不锈钢房分配系统扩展到目前没有浇水或陈旧浇水的其余 27 个动物房； 2）根据最近完成的动物设施总体规划改造医学科学研究大楼一号楼（MSRB I），作为全校园啮齿动物再衍生的核心。拟议的 MSRB I 改造包括拆除现有的动物房隔离隔间、安装消毒器、重新铺设所有地板、购买通风的啮齿动物笼架以及所需的再衍生设备。这些目标中的每一个也将有助于增加两个设施的住房容量，帮助满足不断增长的动物数量的需求。本申请中描述的设备和改进需要继续我们的设施现代化，为动物提供最高质量的护理并维持教师的研究工作。