PhD Training Program in Virology and Gene Therapy

病毒学和基因治疗博士培训项目

基本信息

批准号：
10711192
负责人：
ROBERTO B. CATTANEO
金额：
$ 15.37万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10711192
关键词：
Doctor of Philosophy Training Programs gene therapy virology

项目摘要

Project Summary Unifying scientific principles in the life sciences continue to be discovered in viral systems. Gene therapy and oncolytic virotherapy depend on viral vectors. Awareness that a deep understanding of fundamental virology is necessary for the development of gene therapy led to the foundation of the Virology and Gene Therapy (VGT) track of Mayo Clinic Graduate School of Biomedical Sciences (MCGSBS) in 2004; since 2018 the NIH supports three of its best pre-doctoral students. Ph.D. training leverages the strength of basic research and the robust translational infrastructure at Mayo Clinic. Training is performed in the laboratories of 22 VGT faculty members. Eight are from the Department of Molecular Medicine, three from Medical Oncology, two each from Infectious Diseases, Hematology, and Biochemistry/Molecular Biology. The others are from five different departments. The faculty is united by leadership in research on viruses, vectors, mechanisms of human disease, cancer treatment, and gene therapy. VGT popularity is based in part on its unique training opportunities in both virology and the translation of viral and gene therapeutics. During the entire time of their thesis the students engage in a full array of programmatic activities including journal clubs, seminar series, an annual retreat and national scientific meetings. Requirements for the VGT track conform to the general requirements of MCGSBS. Continued NIH support of three trainees would allow further development of this successful and innovative program.

项目概要在病毒系统中不断发现生命科学中统一的科学原理。基因治疗和溶瘤病毒疗法依赖于病毒载体。认识到对基础病毒学的深刻理解是基因治疗发展所必需的，导致了病毒学和基因治疗（VGT）的基础 2004年进入梅奥诊所生物医学科学研究生院（MCGSBS）；自 2018 年起，NIH 支持三位最优秀的博士前学生。博士培训利用基础研究的力量和强大的梅奥诊所的转化基础设施。培训在 22 名 VGT 教员的实验室中进行。八名来自分子医学科，三名来自肿瘤内科，各两名来自感染科疾病、血液学和生物化学/分子生物学。其他人来自五个不同的部门。这教师们在病毒、载体、人类疾病机制、癌症治疗、和基因治疗。 VGT 的受欢迎程度部分取决于其在病毒学和病毒学方面独特的培训机会病毒和基因疗法的翻译。在整个论文期间，学生们进行了一系列的活动的计划活动，包括期刊俱乐部、研讨会系列、年度务虚会和国家科学会议。 VGT 赛道的要求符合 MCGSBS 的一般要求。继续美国国立卫生研究院三名学员的支持将使这一成功且创新的计划得到进一步发展。