Cancer and Leukemia Group B

癌症和白血病 B 组

• 批准号: 6741456
• 负责人: DAVID D HURD
• 金额: $ 26.15万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6741456
• 关键词: AIDS related neoplasm /cancer; St Johns wort; aging; alternative medicine; antineoplastics; automated medical record system; bioimaging /biomedical imaging; bone marrow transplantation; breast neoplasms; cancer prevention; cancer registry /resource; carmustine; carotenoids; chemoprevention; chimeric proteins; cis platinum compound; clinical research; clinical trial phase I; clinical trial phase II; clinical trial phase III; combination cancer therapy; combination chemotherapy; cooperative study; cyclophosphamide; diphtheria toxin; doxorubicin; drug resistance; finasteride; fluorescent in situ hybridization; fluorouracil; gastrointestinal neoplasms; gemcitabine; ginkgo biloba; health care cost /financing; health disparity; hormone therapy; human genetic material tag; human subject; human therapy evaluation; immunoconjugates; interleukin 2; leucovorin; leukemia; lymphoma; melanoma; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer epidemiology; neoplasm /cancer genetics; neoplasm /cancer immunotherapy; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neoplasm /cancer vaccine; nutrition aspect of cancer; oncology nursing; paclitaxel; pathology; patient oriented research; prostate neoplasms; psychology; quality of life; respiratory neoplasm; soybeans; tamoxifen; tissue resource /registry; vitamin D; weight loss

DESCRIPTION (provided by applicant): This Ul0 application is in support of the CALGB Cooperative Group Clinical Trials conducted through the Wake Forest University School of Medicine (WFUSM) and its affiliate Members. WFUSM has been continuously awarded a CALGB U10 Grant for 45 years (CA03927) as the key support of the infrastructure for data management, the required administrative interactions with our Affiliate Members, and for the support of scientific and administrative contributions to CALGB. In addition to support for the Main Member, this U10 Grant supports the oversight of activity at our two current Affiliate Members, East Carolina University, Greenville, North Carolina and Carolina Oncology Associates of Salisbury, Salisbury, North Carolina. The specific aims of this grant application are: * To increase our scientific contributions to Disease and Modality Committee activities * To enhance the participation of our clinical research investigators through the development of pilot data at the Comprehensive Cancer Center of Wake Forest University that can be developed into CALGB protocols * To expand the Affiliate Network of the Comprehensive Cancer Center of Wake Forest University in order to provide improved care of the cancer patient through access to CALGB Cancer Clinical Trials * To provide a clinical trials mechanism by which minority populations can accrue to clinical trails; to improve their proportional participation in clinical trials research; and to develop specific strategies to address regional barriers to minority recruitment and retention in clinical research studies * To continue our participation as a funded Prevention Member Center

描述（由申请人提供）：本 U10 申请支持通过维克森林大学医学院 (WFUSM) 及其附属成员进行的 CALGB 合作组临床试验。 WFUSM 已连续 45 年获得 CALGB U10 拨款 (CA03927)，作为数据管理基础设施、与附属会员所需的行政互动的关键支持，以及对 CALGB 科学和行政贡献的支持。除了支持主要会员外，这笔 U10 拨款还支持对我们目前的两个附属会员（北卡罗来纳州格林维尔的东卡罗来纳大学和北卡罗来纳州索尔兹伯里的卡罗来纳肿瘤协会）的活动进行监督。该拨款申请的具体目标是： * 增加我们对疾病和模式委员会活动的科学贡献 * 通过在维克森林大学综合癌症中心开发可开发为 CALGB 协议的试点数据，增强我们的临床研究人员的参与 * 扩大维克森林大学综合癌症中心的附属网络，以便通过 CALGB 癌症临床试验为癌症患者提供更好的护理 * 提供临床试验机制，少数群体可以通过该机制获得临床试验；提高他们参与临床试验研究的比例；并制定具体战略，解决临床研究中招募和保留少数群体的区域障碍 * 作为受资助的预防会员中心继续参与