SELENIUM AND VITAMIN E CANCER PREVENTION TRIAL (SELECT)

硒和维生素 E 预防癌症试验（选择）

• 批准号: 7607668
• 负责人: DAVID D HURD
• 金额: $ 1.15万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607668
• 关键词: African American; Age-Years; Cancer Prevention Trial; Clinical; Colorectal Cancer; Computer Retrieval of Information on Scientific Projects Database; Enrollment; Funding; Goals; Grant; Institution; Intake; Lung; Malignant Neoplasms; Malignant neoplasm of prostate; Placebos; Recruitment Activity; Research; Research Personnel; Resources; Selenium; Selenium/vitamin E; Source; United States National Institutes of Health; Universities; Vitamin E; Vitamins; aged; cancer diagnosis; forest; medical schools; men; prevent

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Prostrate cancer is the most common cancer diagnosed among men. Recently two studies have suggested that vitamin E and selenium intake may prevent prostate cancer. The goal of SELECT is to compare the effects (good and bad) of selenium, vitamin E, selenium plus vitamin E and placebo on the occurrence of prostate cancer. Secondary goals are to determine the effects of these supplements on the occurrence of lung and colorectal cancer and all other cancers combined. Nationwide there will be 32,400 men taking part in the study. SELECT will include men aged 55 and older (African American men my be 50 years of age and older), with a goal of 20% of those enrolled being minorites. The Wake Forest University School of Medicine clinical center will recruit 250 men over five years.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 俯卧癌是男性中最常见的癌症。 最近，两项研究表明，维生素E和硒的摄入量可能预防前列腺癌。 选择的目的是比较硒，维生素E，硒以及维生素E和安慰剂对前列腺癌的影响（好与坏）。 次要目标是确定这些补充剂对肺和结直肠癌的发生以及所有其他癌症的影响。在全国范围内，将有32,400名男性参加这项研究。 选择将包括55岁及以上的男性（非洲裔美国男人，我的50岁及以上），目标是20％的人是少数人。 维克森林大学医学院临床中心将在五年内招募250名男性。