Mentorship and Research in HIV and Addiction Prevention Among Traumatized Youth

对受创伤青少年进行艾滋病毒和成瘾预防的指导和研究

基本信息

批准号：
9294042
负责人：
CARLA KMETT DANIELSON
金额：
$ 18.05万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-01 至 2020-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9294042
关键词：
AIDS prevention Achievement Address Adolescent Aftercare Alcohol consumption Alcohol or Other Drugs use Area Award Behavioral Sciences Caregivers Caring Child Abuse and Neglect Childhood Clinical Clinical Research Clinical Sciences Comorbidity Country Data Dedications Development Drug Targeting Drug usage Education Educational Curriculum Evaluation Evidence based treatment Exposure to Faculty Family Feasibility Studies Feeling Funding Glean Goals HIV HIV Infections HIV risk Health Health Technology Human immunodeficiency virus test Individual Infection prevention Instruction Internships Interview Leadership Learning Life Experience Longevity Mental Depression Mentors Mentorship Methods Mid-Career Clinical Scientist Award (K24)Modeling National Institute of Drug Abuse Oral cavity Outcome Population Post-Traumatic Stress Disorders Postdoctoral Fellow Preparation Prevention Preventive Intervention Procedures Process Protocols documentation Psychiatry Psychologist Psychology Public Health Publications Randomized Reaction Recruitment Activity Reporting Research Research Design Research Personnel Research Project Grants Research Training Resources Risk Risk Behaviors Risk Factors Risk Reduction Role Science Scientist Sex Education Sexual abuse Signal Transduction Specific qualifier value Stress Substance Use Disorder Substance abuse problem Surveys Swab Tablets Technology Teenagers Test Result Testing Time Training Trauma United States National Institutes of Health Update Violence Vulnerable Populations Work Youth addiction alcohol prevention base checkup examination condoms cost design early onset substance use early-career faculty effective intervention evidence base experience follow up assessment follow-up handheld mobile device high risk high risk behavior high risk sexual behavior innovation interactive tool interest lifetime risk mHealth new technology patient oriented patient oriented research physical abuse pre-doctoral programs public health priorities public health relevance sex risk sexual trauma skills stem substance use prevention tool training opportunity traumatic event usability web-accessible

项目摘要

DESCRIPTION (provided by applicant): The purpose of this K24 proposal is to enhance exponentially Dr. Carla Kmett Danielson's mentorship and research program in innovative approaches to risk reduction of HIV infection and addiction among adolescents, with a particular focus on trauma-exposed populations. Dr. Danielson, a clinical psychologist and scientist, is the ideal candidate for this mechanism. She has sustained continuous federal-funding of her patient oriented research (POR) since 2005, which has provided the framework for her mentorship of 19 junior investigators contributing to the science of substance abuse comorbidity with high-risk sexual behaviors and trauma. Her mentees, who have included early career faculty, postdoctoral fellows, and predoctoral psychology interns, have made significant contributions to the HIV prevention, substance abuse, and traumatic stress fields through high-impact publications and independent lines of NIH-funded research. Dr. Danielson's long-standing dedication and achievements in POR mentorship are further evidenced through her leadership roles as PI of an NIH-funded T32 Program dedicated to clinical research training in traumatic stress and its sequelae across the lifespan and as Co-Chair for the Faculty Mentorship Program in MUSC's Department of Psychiatry and Behavioral Sciences (currently ranked 7th in the country for NIH funding). The proposed K24 award will be essential in providing time and resources necessary for the candidate to formalize, expand, and sustain her mentoring program and capacity, further stimulate the research program of her mentees (e.g., through a proposed trainee pilot award program and new training opportunities) and augment her research skills and growing program of research in e- and m-health technologies for traumatized adolescents at risk for HIV infection and addiction. Innovative research proposed by Dr. Danielson under the K24 involves development and evaluation of a dynamic, technology-based prevention tool-kit (electronic HIV-sex Education and Addiction Risk for Traumatized Teens; eHEARTT). The toolkit will enhance the quality, accessibility, and efficacy of HIV- risk and substance use prevention interventions for adolescents receiving trauma-focused treatment. Specific aims of the research are to: 1) Develop the eHEARTT toolkit to support delivery of evidence-based HIV and substance use prevention interventions during the delivery of trauma-focused treatment (TF-CBT); 2) Conduct usability tests of the eHEARTT toolkit with teens, caregivers, and clinicians to guide refinements; and 3) Conduct a randomized controlled feasibility trial with 40 families to evaluate TF-CBT plus eHEARTT in comparison to TF-CBT plus a risk behavior electronic Resource List through a 6-month post-treatment follow- up assessment. These aims harmonize well with Dr. Danielson's proposed mentorship activities and current federally-funded research projects in the areas of HIV prevention, substance use risk reduction, and trauma among teens. The proposed research affords rich training opportunities for her mentees (early career faculty, postdoctoral fellows, and predoctoral psychology interns with an emphasis on trainees from groups under- represented in clinical science) and will invigorate new directions in POR with teens at risk for HIV infection and addiction. The proposed work is directly in line with NIDA priorities and funding announcements that call for research designed to evaluate the application of new technologies for delivering adapted prevention interventions targeting drug and alcohol use and prevention of HIV acquisition.

描述（由申请人提供）：本 K24 提案的目的是大幅加强 Carla Kmett Danielson 博士在减少青少年 HIV 感染和成瘾风险的创新方法方面的指导和研究计划，特别关注遭受创伤的人群。丹尼尔森博士是一名临床心理学家和科学家，是该机制的理想人选。自 2005 年以来，她一直持续为她的以患者为导向的研究 (POR) 提供联邦资助，该研究为该机制提供了框架。她的指导者包括早期职业教师、博士后研究员和博士前心理学实习生，通过高影响力的出版物和 NIH 博士资助的独立研究领域，为艾滋病毒预防导师、药物滥用和创伤应激领域做出了重大贡献。 Danielson 在 POR 指导方面的长期奉献和成就通过她作为 PI 的领导角色得到了进一步证明。 NIH 资助的 T32 计划致力于创伤性应激及其终生后遗症的临床研究培训，并担任 MUSC 精神病学和行为科学系教师指导计划的联合主席（目前在 NIH 资助中排名全国第七）。拟议的 K24 奖项对于为候选人提供必要的时间和资源至关重要，以正式确定、扩展和维持她的指导计划和能力，进一步刺激其学员的研究计划（例如，通过拟议的实习生试点奖励计划和新的培训机会），并增强她的研究技能和不断发展的针对面临艾滋病毒感染和成瘾风险的受创伤青少年的电子和移动医疗技术研究计划。丹尼尔森在 K24 下涉及开发和评估一个动态的、基于技术的预防工具包（针对创伤青少年的电子艾滋病毒性教育和成瘾风险；eHEARTT）。该工具包将提高质量、可访问性和有效性。针对接受创伤治疗的青少年的艾滋病毒风险和药物使用预防干预措施该研究的具体目标是： 1) 开发 eHEARTT 工具包，支持在创伤期间提供基于证据的艾滋病毒和药物预防使用干预措施。重点治疗 (TF-CBT)；2) 与青少年、护理人员和支持者一起进行 eHEARTT 工具包的可用性测试，以指导改进；3) 对 40 个家庭进行随机对照可行性试验，以评估 TF-CBT plus eHEARTT 与 TF-CBT 相比，加上通过 6 个月治疗后随访评估的风险行为电子资源列表，这些旨在与 Danielson 博士提议的指导活动和当前联邦资助的以下领域的研究项目良好协调。拟议的研究为她的学员（早期职业教师、博士后研究员和博士前心理学实习生，重点是来自代表性不足群体的学员）提供了丰富的培训机会。拟议的工作直接符合 NIDA 的优先事项和资助公告，这些公告呼吁开展旨在评估新技术应用以提供适应性预防的研究。针对吸毒和酗酒以及预防艾滋病毒感染的干预措施。