19th and 20th International Symposium on Cells of the Hepatic Sinusoid to be held in 2017 in Galway, Ireland and 2019 in Sydney, Australia.

第 19 届和第 20 届肝正弦细胞国际研讨会将于 2017 年在爱尔兰戈尔韦和 2019 年在澳大利亚悉尼举行。

• 批准号: 9397881
• 负责人: LAURA E. NAGY
• 金额: $ 2.5万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9397881
• 关键词: Alcoholic Liver Diseases; Alcohols; Anatomy; Area; Australia; Award; Basic Science; Biology; Cell Communication; Cell physiology; Cells; Cellular biology; Clinical; Clinical Investigator; Clinical Research; Collaborations; Communities; Complex; Country; Data; Development; Developmental Biology; Disabled Persons; Discipline; Discontinuous Capillary; Disease; Endothelial Cells; Environment; Event; Functional disorder; Genetic; Goals; Growth and Development function; Health; Hepatic; Hepatic Stellate Cell; Hepatocyte; Hepatology; Homeostasis; Individual; Inflammation; International; Ireland; Lead; Liver; Liver Fibrosis; Liver diseases; Malignant neoplasm of liver; Methodology; Modality; Molecular; Natural Killer Cells; Nature; Operative Surgical Procedures; Oral; Outcome; Participant; Pathogenesis; Pathologic; Physicians; Physiology; Population; Postdoctoral Fellow; Process; Recruitment Activity; Reperfusion Injury; Request for Applications; Research; Research Personnel; Resource Sharing; Role; Science; Scientist; Signal Transduction; Steatohepatitis; Therapeutic; Translational Research; Travel; Woman; alcohol research; cell type; ethnic minority population; frontier; hepatic sinusoid; innovation; interest; lectures; liver development; liver injury; liver transplantation; macrophage; meetings; multidisciplinary; novel; novel diagnostics; novel therapeutics; oncology; posters; problem drinker; racial and ethnic; response; social; symposium; synergism; translational scientist

ABSTRACT This R13 application requests support for the 19th and 20th International Symposium on Cells of the Hepatic Sinusoid (ISCHS) to be held in Galway, Ireland in June 2017 and Sydney, Australia in June 2019. The application requests support for the participation of invited expert speakers, as well as for young clinical and basic investigators. The goal of the ISCHS is to bring together an international group of multidisciplinary scientists, including established and new investigators, as well as pre- and post-doctoral trainees, who are interested in the common questions: “How does the cross-talk between different liver cell types in the hepatic sinusoid facilitate liver development and growth, homeostasis and pathological outcomes in disease?”. Participants at the meeting will present cutting edge, high quality research which begins to identify novel molecular and cellular interactions within the liver sinusoid. There are surprising gaps in our understanding of this basic unit of functional activity in the liver; advances in hepatic sinusoidal cell biology are critical to understanding the cellular basis of alcoholic liver disease (ALD). The ISCHS represents the only international organization which gathers leading investigators in liver biology and hepatocellular cross talk from around the world. This meeting will facilitate and promote: 1) international collaborations between different countries with populations differing in their genetics and social backgrounds who suffer from ALD, 2) resource sharing between international investigators, generating synergy and unique ideas and 3) interaction of trainees at the international level. Taken together, the unique environment of the ISCHS is an ideal format for cutting-edge interactions on the potential implications of their research into the pathogenesis of ALD, helping to synergize research that will fill these gaps and advance the frontier of research in ALD and development of preventative and therapeutic treatments.

抽象的 此 R13 申请请求支持第 19 届和第 20 届肝细胞国际研讨会 Sinusoid (ISCHS) 将于 2017 年 6 月在爱尔兰戈尔韦和 2019 年 6 月在澳大利亚悉尼举行。 申请请求支持受邀专家演讲者以及年轻临床和 ISCHS 的目标是汇集一个由多学科组成的国际小组。 科学家，包括已建立的和新的研究人员，以及博士前和博士后实习生，他们 对常见问题感兴趣：“肝脏中不同类型肝细胞之间的串扰是如何进行的？ 正弦波促进肝脏发育和生长、体内平衡和疾病的病理结果？” 会议参与者将展示尖端、高质量的研究成果，这些研究成果开始识别新颖的 我们对肝窦内分子和细胞相互作用的理解存在惊人的差距。 肝脏功能活动的这一基本单位；肝窦细胞生物学的进展对于 ISCHS 是了解酒精性肝病 (ALD) 细胞基础的唯一国际组织。 该组织聚集了来自世界各地的肝脏生物学和肝细胞交流领域的领先研究人员 本次会议将促进和促进：1）不同国家之间的国际合作。 患有 ALD 的不同遗传和社会背景的人群，2）资源共享 国际调查人员之间，产生协同作用和独特的想法，以及 3) 受训人员的互动 综合起来，ISCHS 的独特环境是尖端技术的理想模式。 他们的研究对 ALD 发病机制的潜在影响进行互动，有助于协同作用 研究将填补这些空白并推进 ALD 的研究前沿和预防性药物的开发 和治疗方法。