Evaluation of Traumatic Injuries in HCV During Surgery

手术期间 HCV 创伤的评估

• 批准号: 6683331
• 负责人: DENISE M KORNIEWICZ
• 金额: $ 24.99万
• 依托单位: UNIVERSITY OF MIAMI CORAL GABLES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2005-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6683331
• 关键词: clinical research; health care personnel; human subject; injury prevention; laboratory accident /infection; occupational hazard; surgery; surgery material /equipment

DESCRIPTION (provided by the applicant): There are over 8 million health care workers (HCW in the U.S. and approximately 600,000-1 million needlesticks occur resulting in 1000 new cases of HIV, HBV, HCV among HCW. Recent increases in the rate of needlestick/sharp injuries and exposure to bloodborne pathogens has been reported to be greater than 50 percent in HCW who work in the operating room (OR) as compared to other HCW in other settings. Most important, 22 percent of all needlestick injuries have been reported by surgical personnel with 33 percent of the injuries occurring in the surgical field, 25 percent occurring at the surgical site, 59 percent occurring with the non-dominant hand. An alternating block design (four six month blocks) is proposed to: 1) investigate the factors associated with needlestick/sharp injury during a surgical episode and 2) to evaluate specific surgical factors (length of surgery, surgical instrumentation, handedness, use of indicator gloves for needlestick/sharp injury, sequence of surgical cases) that impact on the rate of traumatic (needlestick/sharp) injury among HCW during surgery. During a 24-month data collection period all operating room personnel involved in the study will be trained to use an indicator glove and medical devices (blunt suture needles and retractable scalpels) engineered to reduce the rate of needlestick/sharp injuries. Data will be collected by circulating room nurses for type of surgery, HCW identification, role of HCW, surgical instruments used during a surgical episode, and numbers of glove changes during the episode. Following the surgical event, all gloves will be collected, visually inspected for defects, cuts, and holes and tested for barrier integrity via the standardized FDA waterleak test method (1000cc/2 min.). Multivariate analysis will be conducted and logistic regression to determine the factors predictive of needlestick/sharp injuries to OR personnel.

描述（由申请人提供）：有超过 800 万医疗保健 工作人员（美国的 HCW）大约发生 600,000-100 万次针刺 导致医护人员中新增 1000 例 HIV、HBV、HCV 病例。最近的增加 针刺伤/锐器伤和接触血源性病原体的发生率 据报道，超过 50% 的医护人员在运营部门工作 房间 (OR) 与其他环境中的其他医护人员相比。最重要的是，22 手术人员报告的所有针刺伤百分比 33% 的伤害发生在手术部位，25% 发生在手术部位，59% 发生在非优势部位 手。 建议采用交替区块设计（四个六个月区块）来：1) 调查与针刺/锐器伤害相关的因素 手术次数和 2) 评估特定的手术因素（手术时间长度） 手术、手术器械、惯用手、指示手套的使用 影响手术率的针刺伤/锐器伤、手术顺序） 医护人员在手术期间遭受外伤（针刺/锐器）伤害的情况。期间 24个月的数据收集期所有参与手术的手术室人员 研究人员将接受训练以使用指示手套和医疗设备（钝器） 缝合针和可伸缩手术刀）旨在降低 针刺伤/锐器伤。数据将由循环室护士收集 手术类型、医护人员身份、医护人员的角色、使用的手术器械 在手术期间，以及手术期间更换手套的次数。 手术后，所有手套将被收集并进行目视检查 缺陷、切口和孔洞，并通过以下方法测试屏障完整性 标准化 FDA 漏水测试方法（1000cc/2 分钟）。 将进行多变量分析和逻辑回归以确定 手术室人员发生针刺/锐器伤害的预测因素。