Multi-Resolution Corneal Topography (MRCT)

多分辨率角膜地形图 (MRCT)

• 批准号: 6642624
• 负责人: Edwin Jay Sarver
• 金额: $ 9.18万
• 依托单位: SARVER AND ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6642624
• 关键词: bioimaging /biomedical imaging; computer assisted diagnosis; computer program /software; computer system design /evaluation; computer system hardware; cornea disorder; diagnosis design /evaluation; digital imaging; eye disorder diagnosis

DESCRIPTION (provided by applicant): Objective: Develop a new reflection-based corneal topographer that provides more reliable and accurate measurements of the anterior corneal surface than those of commercially available systems. Specific Aims: Determine the feasibility of the multi-resolution corneal topograher (MRCT) by: (1) developing prototype color multiple-resolution reflection target, optical breadboard, and prototype software; (2) integrating components; and (3) evaluating the performance of the system. Health Relatedness: Provide more accurate anterior surface measurements needed for research and vision intervention techniques that correct higher-order aberrations. Methods: The project incorporates a novel reflection target design, reconstruction algorithm, and a high resolution digital camera. We refer to this new system as the multiple-resolution corneal topographer (MRCT) because the reflection target employs color sinusoidal profiles that provide three simultaneous multiple-resolution ring images. Technological Innovation: The MRCT system represents a new way of measuring the anterior corneal surface that will be more robust and accurate than other commercially available corneal topography systems. Our approach is a technological innovation over traditional reflection target methods in that it incorporates a color sinusoidal ring target to acquire multiple-resolution ring images (4, 16, and 64 rings) in a single exam.

描述（由申请人提供）： 目的：开发一种新的基于反射的角膜地形图仪，与市售系统相比，它可以提供更可靠、更准确的前角膜表面测量。 具体目标：通过以下方式确定多分辨率角膜地形图仪（MRCT）的可行性：（1）开发原型彩色多分辨率反射目标、光学面包板和原型软件； (2)集成组件； (3)评估系统的性能。健康相关性：提供纠正高阶像差的研究和视力干预技术所需的更准确的前表面测量。 方法：该项目采用了新颖的反射目标设计、重建算法和高分辨率数码相机。我们将这个新系统称为多分辨率角膜地形图仪 (MRCT)，因为反射目标采用彩色正弦轮廓，可同时提供三个多分辨率环形图像。 技术创新：MRCT 系统代表了一种测量角膜前表面的新方法，比其他市售角膜地形图系统更强大、更准确。我们的方法是对传统反射目标方法的技术创新，因为它结合了彩色正弦环目标，可在单次检查中获取多分辨率环图像（4、16 和 64 环）。