Basis of intonation disturbance following brain damage

脑损伤后语调障碍的基础

• 批准号: 6695417
• 负责人: AMEBU K SEDDOH
• 金额: $ 7.01万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6695417
• 关键词: aphasia; auditory discrimination; behavioral /social science research tag; brain injury; clinical research; hearing; human middle age (35-64); human old age (65+); human subject; language disorders; neural information processing; phonology; psychoacoustics; speech recognition; visual stimulus

DESCRIPTION (provided by applicant): This research project is aimed at understanding the basis of intonation disturbance in patients with aphasia. Specifically, it seeks to determine whether the root of intonation disorder in this population is attributable to primary linguistic deficit or to underlying speech timing problems related to utterance length. Three experiments, two acoustic and one perceptual, are proposed. In the acoustic studies, subjects will be presented matched statements and echo questions of two lengths to produce. Fundamental frequency (F0) contours associated with the productions will be decomposed into linguistically and nonlinguistically relevant components in order to determine if intonation abnormalities exhibited by the patients are related to linguistic or nonlinguistic underlying deficit. In addition to the F0 evaluation, aspects of duration will be measured to assess speech timing. To understand whether intonation disorder is attributable to primary speech timing problems related to utterance length, the performance of subjects on spectral and temporal measures across the two stimulus lengths will be compared. The perceptual experiment will be in three sessions. In session one, subjects will be presented tape recorded statements and (echo) questions to discriminate. In session two, the same sentences sliced into two parts that correspond to terminal and preterminal F0 regions will be presented to subjects to identify each as part of a statement or part of a question. This approach is intended to determine if the acoustic (F0) information in one part of the sentence is more difficult for the patients to process compared to the information in the other part. In session 3, subjects will be presented tape recorded nonsense stimuli structured as statements and questions to identify as 'statement-like' or 'question-like' utterances. This is in order to understand whether problems of intonation perception for the patients are related to nonlinguistic underlying deficit. Few studies have examined the basis of intonation disturbance in aphasia. Given that the study of a language disorder can shed light on the normal form of that aspect of language, this study will contribute to the elucidation of the nature of not only intonation disorder, but also normal intonation. The proposed paradigm involving decomposition of the F0 contours into linguistically and nonlinguistically relevant components is a unique approach that has ramifications for diagnosis and management of the disorder.

描述（由申请人提供）：该研究项目旨在了解失语症患者语调障碍的基础。具体来说，它试图确定该人群中语调障碍的根源是否可归因于主要语言缺陷或与话语长度相关的潜在语音计时问题。提出了三个实验，两个是声学的，一个是感知的。在声学研究中，将向受试者提供匹配的陈述和回声两种长度的问题。与产物相关的基频 (F0) 轮廓将被分解为语言和非语言相关成分，以确定患者表现出的语调异常是否与语言或非语言潜在缺陷有关。除了 F0 评估之外，还将测量持续时间的各个方面以评估语音时序。为了了解语调障碍是否归因于与话语长度相关的主要语音计时问题，将比较受试者在两个刺激长度上的频谱和时间测量的表现。感知实验将分三期进行。在第一节中，将向受试者提供录音陈述和（回声）问题以进行区分。在第二节中，将向受试者呈现与末端和前末端 F0 区域相对应的相同句子，以将其分为两个部分，以将每个部分识别为陈述的一部分或问题的一部分。该方法旨在确定句子某一部分中的声学 (F0) 信息是否比另一部分中的信息更难于患者处理。在第 3 节中，受试者将看到由陈述和问题构成的录音无意义刺激，以识别“类似陈述”或“类似问题”的话语。这是为了了解患者的语调感知问题是否与非语言潜在缺陷有关。很少有研究探讨失语症语调障碍的基础。鉴于对语言障碍的研究可以揭示语言该方面的正常形式，这项研究不仅有助于阐明语调障碍的性质，而且有助于阐明正常语调的性质。所提出的范式涉及将 F0 轮廓分解为语言和非语言相关成分，这是一种独特的方法，对疾病的诊断和管理有影响。