Health Promotion for Positives: A Randomized Trial with HIV Positive Black Men

积极健康促进：艾滋病毒阳性黑人男性的随机试验

基本信息

批准号：
8985689
负责人：
JOHN BARTON JEMMOTT
金额：
$ 39.91万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-03-21 至 2018-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8985689
关键词：
AIDS prevention AIDS-Related Opportunistic Infections Adherence Affect African American Age Aging Anti-Retroviral Agents Applications Grants Attention Behavior Behavioral Blood Pressure Body mass index Budgets Cardiovascular Diseases Centers for Disease Control and Prevention (U.S.)Chronic Chronic Disease Colon Carcinoma Comorbidity Complement Computer Assisted Control Groups Couples Data Diabetes Mellitus Diet Evidence based intervention Expectancy Future General Population Guidelines HIV HIV Infections HIV Seropositivity Health Health Promotion Health behavior Highly Active Antiretroviral Therapy Hour Hypertension Individual Intervention Interview Kidney Diseases Life Link Long-Term Effects Malignant Neoplasms Malignant neoplasm of prostate Measures Mediating Mediator of activation protein Medical Records Morbidity - disease rate Outcome Participant Patient Self-Report Persons Physical Fitness Physical activity Physiological Prevention Prostate Randomized Randomized Controlled Trials Research Risk Screening for Prostate Cancer Self Efficacy Testing Time Treatment Efficacy United States Vulnerable Populations Waist-Hip Ratio Walking base behavior change comparative efficacy design effective therapy efficacy testing empowered experience fitness fruits and vegetables health disparity high risk innovation interest man men mortality post intervention primary outcome racial health disparity randomized trial response screening sex social cognitive theory successful intervention theories waist circumference

项目摘要

PROJECT SUMMARY: This application is in response to RFA-MD-12-001, "NIMHD Health Disparities Research (R01)." African American men who are infected with HIV are living longer and are being impacted by the same chronic diseases that affect the general population of African American men over 40. To be sure, African American men, in general, have disproportionately high rates of cardiovascular disease, hypertension, diabetes, kidney disease, and cancer, particularly prostate and colon cancer. However, HIV infection is associated with an increased risk for co-morbidity from chronic diseases. This increased risk is heightened by HIV infection, but also its treatment with certain agents used in highly active antiretroviral therapy (HAART) combinations. Many of these chronic illnesses have behavioral components-risk is influenced by what people do and don't do, their diet, and the amount of physical activity they get. Although the high risk for multiple behavior-linked chronic diseases among HIV-positive individuals has been recognized, there is a lack of evidence-based intervention specifically tailored to their needs. Hence, the broad objective is to reduce the risk of chronic diseases among HIV positive African American men. The Specific Aims are to test the efficacy of a theory- based, contextually appropriate health promotion intervention in inducing positive changes in behaviors linked to risk of chronic diseases among HIV positive African American men age 40 years or older and to identify the theoretical variables that mediate its efficacy. The study will utilize a randomized controlled trial. The participants will be 384 African American HIV positive men age 40 or older who are receiving HAART for HIV. The men will be randomized to a theory-based contextually appropriate health promotion intervention that involves three, 3-hour weekly intervention sessions or an attention-control group. The health promotion intervention will be an adaptation of an intervention based on social cognitive theory integrated with formative research and found to be efficacious in increasing adherence to 5-a-Day diet and physical activity guidelines and prostate cancer screening guidelines in the applicants' preliminary studies. Data will be collected at baseline, immediately post, 3, 6 and 12 months post intervention, which will permit assessment of the short- term and long-term effects of the intervention and whether the intervention's efficacy varies over time. Audio computer-assisted self-interviewing will be used to assess self-reported adherence to physical activity guidelines, 5-a-Day fruit and vegetable guidelines, prostate screening guidelines, and colon cancer screening guidelines and theoretical mediators of behavior change. Objective outcomes will include health-related fitness (6-minute walk test, 1-minute push-up test, 1-minute sit-up test, sit-and-reach test), physiological variables (blood pressure, body mass index, waist circumference, and waist-hip ratio), and prostate and colon cancer screening based on medical record review.

项目概要：此申请是为了响应 RFA-MD-12-001“NIMHD 健康差异研究 (R01)”。非洲人感染艾滋病毒的美国男性寿命更长，并且受到同样慢性病的影响影响 40 岁以上非裔美国男性总体人群的疾病。可以肯定的是，非裔美国人一般来说，男性患心血管疾病、高血压、糖尿病、肾病的比例极高疾病和癌症，特别是前列腺癌和结肠癌。然而，HIV 感染与慢性病合并症的风险增加。 HIV 感染会加剧这种增加的风险，但是还包括与高效抗逆转录病毒疗法 (HAART) 组合中使用的某些药物进行治疗。许多这些慢性疾病中有行为成分——风险受到人们做什么和不做什么的影响，他们的饮食，以及他们的体力活动量。尽管多种行为相关的风险很高艾滋病毒阳性者中的慢性病已得到承认，但缺乏基于证据的证据专门针对他们的需求进行干预。因此，总体目标是降低慢性病的风险艾滋病毒呈阳性的非裔美国男性中的疾病。具体目标是测试理论的有效性- 基于具体情况的健康促进干预措施，以引起相关行为的积极变化 40 岁或以上 HIV 阳性非裔美国男性患慢性病的风险，并确定调节其功效的理论变量。该研究将采用随机对照试验。这参与者将是 384 名 40 岁或以上、正在接受 HAART 治疗 HIV 的非洲裔美国 HIV 阳性男性。这些男性将被随机分配接受基于理论、适合具体情况的健康促进干预措施，涉及每周 3 次、每次 3 小时的干预课程或注意力控制组。健康促进干预将是基于社会认知理论与形成性相结合的干预的改编研究发现可有效提高对每日 5 次饮食和身体活动指南的遵守率申请人初步研究中的前列腺癌筛查指南。数据收集时间为基线、干预后立即、干预后 3、6 和 12 个月，这将允许评估短期干预措施的短期和长期影响以及干预措施的功效是否随时间变化。声音的将使用计算机辅助自我访谈来评估自我报告的身体活动坚持情况指南、每日 5 种水果和蔬菜指南、前列腺筛查指南和结肠癌筛查行为改变的指导方针和理论中介。客观结果将包括与健康相关的健身（6分钟步行测试、1分钟俯卧撑测试、1分钟仰卧起坐测试、坐姿伸展测试）、生理变量（血压、体重指数、腰围和腰臀比）以及前列腺癌和结肠癌根据病历审查进行筛查。

项目成果

期刊论文数量（2）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Reasoned Action Approach Correlates of Physical Activity Among African American Men Living With HIV: A Cross-Sectional Study.

合理的行动方法与感染艾滋病毒的非洲裔美国男性的身体活动相关：一项横断面研究。

DOI：
发表时间：
2021-01-01
期刊：
影响因子：
0
作者：
Kelly, Terri;Woko, Chioma;Jemmott, Loretta S;Icard, Larry;Chittamuru, Deepti;Jemmott 3rd, John B
通讯作者：
Jemmott 3rd, John B

Reasoned Action Approach Correlates of Fruit and Vegetable Diet Among African American Men Living With HIV: A Cross-Sectional Study.

理性行动方法与感染艾滋病毒的非洲裔美国男性水果和蔬菜饮食的相关性：一项横断面研究。

DOI：
发表时间：
2021
期刊：
影响因子：
0
作者：
Kelly, Terri;Kim, Soojong;Jemmott, Loretta S;Icard, Larry D;Chittamuru, Deepti;Jemmott 3rd, John B
通讯作者：
Jemmott 3rd, John B