Developing climate cohorts to understand health associations and resilience and susceptibility factors in Ghana

开发气候队列以了解加纳的健康关联以及复原力和易感性因素

• 批准号: 10838923
• 负责人: Darby Jack
• 金额: $ 57.27万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-07 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10838923
• 关键词: Affect; Africa; African; Age; Air Pollution; Area; Birth; Blood Pressure; Brazil; Cessation of life; Child; Childhood; China; Chronic Disease; Climate; Cohort Studies; Communities; Conceptions; Country; Data; Data Collection; Data Set; Development; Droughts; Educational workshop; Feedback; Future; Ghana; Goals; Government; Growth; Health; Health Promotion; Household; Individual; Life Cycle Stages; Longitudinal cohort; Maps; Maternal and Child Health; Measures; Mentors; Modeling; Morbidity - disease rate; Mothers; Outcome; Participant; Policies; Population; Positioning Attribute; Precipitation; Predisposition; Pregnancy; Proxy; Randomized; Research; Resolution; Resources; Risk; Rural; Scientist; Standardization; System; Temperature; Time; Training; Variant; Work; climate change; climate data; climate policy; climate science; climate-related health; cohort; cost effective; data repository; data resource; disorder risk; extreme heat; follow-up; food security; global health; indexing; insight; large datasets; low and middle-income countries; mortality; novel; prenatal; pressure; prospective; public health intervention; recruit; research and development; resilience; resilience factor; sex; standardize measure; vapor

Project summary Global health gains achieved over the past half century are at risk of being eroded by climate change, which disproportionately affects low- and middle-income countries (LMICs). In LMICs, scientific and policy planning capacity to incorporate climate compatible strategies into climate sensitive areas like the health sector is severely hampered by the lack of empirically derived estimates of local climate sensitivities from their countries and, critical for policy, an understanding of population-specific resilience and susceptibility factors. Indeed, recent climate sensitivities relied on data from LMICs with large scale administrative data (Brazil, China) as a proxy for the African continent. Despite this major limitation, these data suggest that the effect of temperature on mortality in susceptible groups will be ~50% larger in regions for which there is no available data, such as Africa. We propose to build climate science expertise in Ghana by mentored research and the development of two reinforcing sets of “climate cohorts.” We will leverage the well-characterized, extant Ghana Randomized Air Pollution and Health Study to examine associations between climatic exposures on maternal-child health. We will also begin work with the Kintampo Health and Demographic Surveillance System (KHDSS) to prepare for future climate work leveraging this rich data resource. This work will begin to refine climate health sensitivity estimates, provide key insights into resilience and susceptibility factors, and fill urgently-needed policy and practice-relevant evidence gaps. A long-term goal of this project is to provide a framework for continued climate science in Ghana and a model for other African countries with similar extant cohorts, to collectively catalyze climate research on the African continent.

项目概要 过去半个世纪取得的全球健康成果面临着气候变化侵蚀的风险， 对低收入和中等收入国家 (LMIC) 的影响尤为严重 在 LMIC 中，科学和政策规划。 将气候兼容战略纳入卫生部门等气候敏感领域的能力正在增强 由于缺乏对本国当地气候敏感性的经验估计而受到严重阻碍 事实上，了解特定人群的复原力和易感性因素对政策至关重要。 最近的气候敏感性依赖于具有大规模行政数据（巴西、中国）的中低收入国家的数据作为 尽管存在这一重大限制，但这些数据表明温度的影响。 在没有可用数据的地区，易感群体的死亡率将高出约 50%，例如 非洲。我们建议通过指导研究和开发在加纳建立气候科学专业知识。 两组强化的“气候群体”。我们将利用特征明确的现有加纳随机样本 空气污染与健康研究，旨在研究气候暴露与母婴健康之间的关联。 我们还将开始与 Kintampo 健康和人口监测系统 (KHDSS) 合作，准备 这项工作将开始完善气候健康敏感性。 估计，提供有关复原力和易感性因素的关键见解，并填补急需的政策和 该项目的长期目标是提供一个持续的框架。 加纳的气候科学以及具有类似现有群体的其他非洲国家的模型，共同 促进非洲大陆的气候研究。