Administrative Supplement to U54 HD110347: Development of a Common Processing Pipeline and Visualization Tools for HuBMAP GeoMx Assays

U54 HD110347 的行政补充：用于 HuBMAP GeoMx 检测的通用处理流程和可视化工具的开发

• 批准号: 10825269
• 负责人: LOUISE CHANG LAURENT
• 金额: $ 10万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10825269
• 关键词: 3-Dimensional; Administrative Supplement; Biological Assay; Cell Nucleus; Cells; Characteristics; Collaborations; Data; Data Analyses; Decision Making; Development; Environment; Female; Goals; Human BioMolecular Atlas Program; Image; Mammalian Oviducts; Maps; Placenta; Pregnant Uterus; Proteins; Public Health; Pythons; RNA; Research Support; Standardization; Testing; Transcript; Visualization; Visualization software; data visualization; medical schools; member; nano-string; open source; pregnant; reproductive; tissue mapping; tool

SUMMARY This Administrative Supplement request aims to collaboratively develop and test open-source, GeoMX data visualization and analysis tools required to support research using this data. Members of the Pregnant Female Reproductive Tissue Mapping Center (TMC) will collaborate with members of the HIVE at Harvard Medical School to fill a current gap in GeoMX visualization tools by working closely to develop a visualization tool for Nanostring GeoMx data based on Vitessce (Aim 1) and to support local visualization and configuration (Aim 2).

概括 此行政补充请求旨在协作开发和测试开源 GeoMX 数据 支持使用这些数据进行研究所需的可视化和分析工具。孕妇成员 生殖组织绘图中心 (TMC) 将与哈佛医学院 HIVE 成员合作 学校通过密切合作开发可视化工具来填补当前 GeoMX 可视化工具的空白 Nanostring GeoMx 数据基于 Vitessce（目标 1）并支持本地可视化和配置（目标 2）。