Administrative Core

行政核心

• 批准号: 10689036
• 负责人: R. Sean Morrison
• 金额: $ 50.05万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10689036
• 关键词: Academy; Acceleration; Address; Aging; Agreement; Award; Budgets; California; Caregivers; Caring; Clinical; Code; Collaborations; Communities; Complex; Data; Data Security; Data Set; Data Sources; Dementia; Disease; Drug Prescriptions; Elderly; Ensure; Event; Family; Feedback; Fostering; Funding; Geriatrics; Gerontology; Goals; Health; Health Policy; Health system; Healthcare; Home; Hour; Infrastructure; Institution; Knowledge; Leadership; Learning; Manuals; Medical; Medicine; Mentors; Methodology; Modeling; Monitor; Outcome; Palliative Care; Patients; Personal Satisfaction; Persons; Policies; Population; Population Research; Preparation; Publications; Quality of life; Reporting; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Research Support; Resource Sharing; Resources; Retirement; Role; San Francisco; Scientist; Social Environment; Training Activity; Translating; Translations; United States National Institutes of Health; Universities; Vision; Work; career development; clinical practice; community based care; cost efficient; data dictionary; data management; data resource; epidemiologic data; evidence base; experience; health care quality; health data; hospice environment; human subject; improved; innovation; medical schools; next generation; patient population; population based; programs; remediation; social; trend; Academy; Acceleration; Address; Aging; Agreement; Award; Budgets; California; Caregivers; Caring; Clinical; Code; Collaborations; Communities; Complex; Data; Data Security; Data Set; Data Sources; Dementia; Disease; Drug Prescriptions; Elderly; Ensure; Event; Family; Feedback; Fostering; Funding; Geriatrics; Gerontology; Goals; Health; Health Policy; Health system; Healthcare; Home; Hour; Infrastructure; Institution; Knowledge; Leadership; Learning; Manuals; Medical; Medicine; Mentors; Methodology; Modeling; Monitor; Outcome; Palliative Care; Patients; Personal Satisfaction; Persons; Policies; Population; Population Research; Preparation; Publications; Quality of life; Reporting; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Research Support; Resource Sharing; Resources; Retirement; Role; San Francisco; Scientist; Social Environment; Training Activity; Translating; Translations; United States National Institutes of Health; Universities; Vision; Work; career development; clinical practice; community based care; cost efficient; data dictionary; data management; data resource; epidemiologic data; evidence base; experience; health care quality; health data; hospice environment; human subject; improved; innovation; medical schools; next generation; patient population; population based; programs; remediation; social; trend

RCA PROJECT SUMMARY The overarching goal of our P01, Deploying High Value Longitudinal Population-Based data in Dementia Research (DEVELOP AD RESEARCH), is to create an integrated program of research that considers the wider medical, health system, and social contexts of dementia that are important to patients and families and that have been inadequately considered in prior research. Our specific focus is on research questions that demand the use of population-based data resources and cannot be addressed by more mechanistically focused studies in a timely or cost-efficient manner. The P01 supports research that: a) examines the complex interaction of dementia and other serious illness; b) identifies the impact of clinical and social disruptive events on disease trajectory and outcomes; c) explores medication prescribing in the context of dementia; and d) examines how models of community-based care (hospice and home-based medical care) meet the needs of people with dementia and their families over the duration of illness. Leveraging our track record conducting groundbreaking research employing the rich, comprehensive, and longitudinal data of the HRS and NHATS, we will create the knowledge needed to enhance quality of life for persons with dementia and their caregivers. RCA will provide coordination and oversight of the P01 as well as the vision and leadership needed to advance and to translate our research findings into improvements in care. The specific aims of RCA are: · SA 1: To support scientific innovation for older adults with dementia by ensuring regular, ongoing coordinated scientific interaction, planning, learning and feedback between all cores and projects, and effective use of shared resources with optimal efficiency; · SA 2: To provide day-to-day management, including the preparation of administrative documents; management of fiscal matters of all projects and cores including oversight of all budgets, resources, and sub-contracts; and manage data use agreements, data security, human subjects review; · SA 3: To monitor research progress, implement necessary remediation, and ensure timely publication and dissemination of research findings; · SA 4: To leverage our national roles in the OAIC Network and National Palliative Care Research Center to disseminate our findings, resources, and programming codes and provide “office hours” and resources to early stage investigators across the nation engaged in population-based research programs in dementia. RCA advances population-based research in dementia and its translation into clinical practice through a comprehensive framework of coordinated activities. This framework provides infrastructure for research, nurtures and facilitates collaboration, promotes the use of cutting-edge methodologies, and disseminates results to the scientific and policy communities. RCA also incorporates an innovative focus on career development for early stage investigators and promotes the use of HRS and NHATS for dementia research.

RCA项目摘要 我们的P01的总体目标，在痴呆症中部署高价值的基于纵向人群的数据 研究（发展广告研究）是为了创建一个集成的研究计划，以考虑 痴呆症的广泛医疗，卫生系统和社会环境对患者和家庭很重要， 在先前的研究中未充分考虑。我们的具体重点是研究问题 要求使用基于人群的数据资源，并且无法更机械地解决 集中研究及时或成本效益。 P01支持：a）检查复合物的研究 痴呆和其他严重疾病的相互作用； b）确定临床和社会破坏性事件的影响 关于疾病轨迹和结果； c）探索在痴呆症背景下的药物处方；和D） 检查基于社区护理模型（临终关怀和家庭医疗服务）如何满足 患有痴呆症的人及其家人在疾病期间。利用我们的往绩记录 开创性的研究采用了人力资源管理和NHAS的丰富，全面和纵向数据， 我们将创建所需的知识，以增强痴呆症患者及其护理人员的生活质量。 RCA将提供P01的协调和监督，以及所需的愿景和领导 进步并将我们的研究结果转化为护理的改进。 RCA的具体目标是： SA 1：通过确保常规，持续 协调所有核心和项目之间的科学互动，计划，学习和反馈，以及 有效利用具有最佳效率的共享资源； ·SA 2：提供日常管理，包括准备行政文件； 管理所有项目和核心的财政问题，包括对所有预算，资源和资源的监督 分包合同；并管理数据使用协议，数据安全，人类主题审查； SA 3：监视研究进度，实施必要的修复，并确保及时发布和 研究结果的传播； SA 4：利用我们在OAIC网络和国家姑息治疗研究中心的国家角色 传播我们的发现，资源和编程代码，并提供“办公时间”和资源 全国各地的早期研究人员从事痴呆症的基于人群的研究计划。 RCA通过痴呆症的基于人群的研究及其转化为临床实践 协调活动的全面框架。该框架为研究提供了基础架构， 护士和促进合作，促进尖端方法的使用并传播 结果为科学和政策社区。 RCA还将专注于职业创新 早期研究人员的开发，并促进了HRS和NHAT用于痴呆症研究的使用。