Clinical and Translational Science Award
临床和转化科学奖
基本信息
- 批准号:10674531
- 负责人:
- 金额:$ 1029.98万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-01 至 2026-05-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAddressCOVID-19 pandemicClinical ResearchClinical SciencesClinical Trials DesignClinical and Translational Science AwardsCollaborationsCommunitiesDentalEducationElectronic Health RecordEnvironmentEvaluationEvolutionFacultyFoundationsFriendsGoalsHealthHealth BenefitHealth systemHealthcareHospitalsInfrastructureInstitutionInterdisciplinary StudyLaboratoriesLeadLeadershipLearningMedical centerMedicineMethodsMissionModelingNew YorkNew York CityPatientsPersonal SatisfactionPhasePhysiciansPresbyterian ChurchProblem SolvingProcessProgram DevelopmentPublic HealthPublic Health SchoolsRecording of previous eventsResearchResearch MethodologyResearch PersonnelResourcesSchool NursingSchoolsScienceSpeedStrategic PlanningStrategic visionSurgeonTimeTrainingTranslational ResearchUniversitiesVisionWorkforce Developmentcareercollegedissemination scienceexperienceflexibilityimplementation scienceimprovedinnovationmeetingsmembernovelnovel therapeuticsoperationopioid epidemicprecision medicineprogramssuccesssynergismtranslational pipelineuser-friendly
项目摘要
Contact PD/PI: Reilly, Muredach P
OVERALL: PROJECT SUMMARY/ABSTRACT
Our mission is to improve the health of our patients and communities both locally and nationally through
innovations in clinical and translational research. Our strategic vision is to catalyze all phases of clinical and
translational science (T0-T4), synergize with our partners and stakeholders, and integrate activities within our
hub and across the national Clinical and Translational Science Award (CTSA) Program. To achieve this vision,
we will build on our strong established track-record (e.g., in precision medicine), our plans to tackle important
public-health challenges (e.g., COVID-19 pandemic, the opioid crisis) and to address critical barriers (e.g.,
innovation in use of electronic health records for research, clinical trial designs) as we embrace the CTSA
Program priorities designated in PAR-18-940. Our vision is to transform the health and wellbeing of our
communities in New York City, the nation and the world. To achieve this, we deploy our programs and resources
to develop, demonstrate and disseminate innovations in
clinical and translational science
across the full
translational spectrum.
As a comprehensive CTSA, we offer a broad array of support for trainees, scholars and
investigators across our entire hub which includes Columbia University, the Columbia University Irving Medical
Center, the New York Psychiatric Institute, and New York Presbyterian Hospital. At the same time, we move
flexibly and deeply to address critical scientific or institutional opportunities as well as major public health needs
and gaps. We achieve success by approaching our goals at multiple levels: a) Ongoing strategic planning
including an annual retreat to review operations and identify gaps, needs and opportunities; b) Monthly cross-
cutting “Theme” meetings to enable collaborative problem-solving in addressing gaps and opportunities; c) An
innovative Evaluation and Continuous Improvement strategy using participatory management to integrate
evaluation into program planning and execution; and d) A highly successful, innovative interdisciplinary training
and workforce development program built on a foundation of team science. Central to our efforts to improve
health and wellbeing at personal, community and national levels is our emphasis on strategic collaboration and
dissemination. Thus, we seek to continuously create and refine innovations for an integrated research- and user-
friendly translational research environment at our hub by: Harnessing partnerships across our entire hub;
Transforming collaborations with our local communities, the campus health system and across New York State;
And by accelerating bidirectional dissemination of innovative practices and learnings through collaborations with
the CTSA Program network and beyond.
Project Summary/Abstract Page 221
Contact PD/PI: Reilly, Muredach P
Narrative
The Clinical and Translational Science Award (CTSA) allows Columbia University to support novel programs
whose goal is to speed the transition from scientific discoveries made in the laboratory toward new therapies.
Building on our strong established track-record, we will tackle important challenges and critical barriers to
research. We will facilitate the training of scholars from diverse backgrounds underrepresented in translational
science who are knowledgeable about and available to focus on translational science later in their careers.
联系PD/PI:Reilly,Musedach P
总体:项目摘要/摘要
我们的使命是通过
临床和翻译研究的创新。我们的战略视野是催化临床的所有阶段
转化科学(T0-T4),与我们的合作伙伴和利益相关者协同作用,并在我们的内部进行整合的活动
集线器以及全国临床和转化科学奖(CTSA)计划。为了实现这一愿景,
我们将建立在强大的田径记录中(例如,在精密医学中),我们的计划应对重要
公共卫生挑战(例如Covid-19-19,大流行,阿片类药物危机),并应对关键障碍(例如,
我们拥抱CTSA时使用电子健康记录的创新,临床试验设计)
计划优先级在PAR-18-940中指定。我们的愿景是改变我们的健康和福祉
纽约市,国家和世界的社区。为了实现这一目标,我们部署了我们的程序和资源
发展,演示和传播创新
临床科学
遍及整个
翻译光谱。
作为全面的CTSA,我们为培训,学者和
整个枢纽的调查人员,包括哥伦比亚大学,哥伦比亚大学欧文医学
中心,纽约精神病学院和纽约长老会医院。同时,我们移动
灵活而深入地解决关键的科学或机构机会以及主要的公共卫生需求
和差距。我们通过在多个层面上实现我们的目标来取得成功:a)正在进行的战略规划
包括年度务虚会,以审查操作并确定差距,需求和机会; b)每月交叉
削减“主题”会议,以解决解决差距和机会的协作问题;能
使用参与管理进行创新评估和持续改进策略以整合
评估计划计划和执行; d)非常成功,创新的跨学科培训
和劳动力发展计划以团队科学为基础为基础。我们努力改善的核心
个人,社区和国家层面的健康和福祉是我们对战略合作的重视
传播。这,我们试图继续为集成的研究和用户 -
友好的翻译研究环境在我们的枢纽:利用整个枢纽的合作伙伴关系;
与我们当地社区,校园卫生系统和整个纽约州进行合作;
并通过与与之合作的双向传播创新实践和学习
CTSA程序网络及以后。
项目摘要/摘要页面221
联系PD/PI:Reilly,Musedach P
叙述
临床和转化科学奖(CTSA)允许哥伦比亚大学支持新课程
其目标是加快从实验室中的科学发现向新疗法的过渡。
在我们建立的良好田径记录的基础上,我们将应对重要的挑战和关键障碍
研究。我们将促进对译本不足的潜水者背景的学者的培训
知识渊博并可以专注于后来的转化科学的科学。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Muredach P Reilly其他文献
Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks
单核细胞的单细胞多模式分析揭示了与心血管疾病风险相关的多种表型和变化
- DOI:
10.1101/2024.02.18.580913 - 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Alexander C. Bashore;Chenyi Xue;Eunyoung Kim;Hanying Yan;Lucie Y. Zhu;Huize Pan;Michael D Kissner;Leila S Ross;Hanrui Zhang;Mingyao Li;Muredach P Reilly - 通讯作者:
Muredach P Reilly
1008-184 The effects of pravastatin and atorvastatin on markers of oxidant stress in vivo
- DOI:
10.1016/s0735-1097(04)91877-3 - 发表时间:
2004-03-03 - 期刊:
- 影响因子:
- 作者:
Bonnie Ky;Megan L Wolfe;Anne Burke;Philippe O Szapary;Muredach P Reilly;Jennifer B Dykhouse;Leanne T Bloedon;Garret A FitzGerald;Daniel J Rader - 通讯作者:
Daniel J Rader
Muredach P Reilly的其他文献
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{{ truncateString('Muredach P Reilly', 18)}}的其他基金
Smooth muscle cell-derived cell fates and cellular interactions in atherosclerotic plaque stability in disease progression and regression.
平滑肌细胞衍生的细胞命运和细胞相互作用在疾病进展和消退中动脉粥样硬化斑块的稳定性。
- 批准号:
10567844 - 财政年份:2023
- 资助金额:
$ 1029.98万 - 项目类别:
Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease risk
鉴定导致动脉粥样硬化斑块稳定性和心血管疾病风险的平滑肌细胞基因
- 批准号:
10720225 - 财政年份:2023
- 资助金额:
$ 1029.98万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9402855 - 财政年份:2017
- 资助金额:
$ 1029.98万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9983136 - 财政年份:2017
- 资助金额:
$ 1029.98万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9531432 - 财政年份:2017
- 资助金额:
$ 1029.98万 - 项目类别:
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