Center for the Study of Aphasia Recovery (C-STAR)

失语症康复研究中心 (C-STAR)

基本信息

批准号：
10672777
负责人：
JULIUS FRIDRIKSSON
金额：
$ 11.18万
依托单位：
UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-04-01 至 2026-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10672777
关键词：
Acute Address Age Aphasia Archives Behavioral Biological Markers Blood Brain Injuries Brain imaging Characteristics Chronic Climate Complement Data Data Set Databases Dehydration Diurnal Rhythm Enrollment Exercise Expenditure Frequencies Future Gender Genetic Global Warming Health Heat Waves Hospitalization Humidity Hyperviscosity Image Impairment Incidence Individual Injury Intervention Ischemic Stroke Language Language Therapy Lead Left Lesion Life Style Location Maps Measures Medical Records Nature Outcome Pattern Prognosis Recovery Reporting Research Resolution Risk Factors Seasonal Variations Seasons Socioeconomic Status South Carolina Speech Speech Therapy Standardization Stroke Stroke Belt Symptoms Temperature Time United States Work acute stroke aphasia recovery archive data archived data behavior measurement behavioral impairment brain health chronic stroke climate impact disability expectation imaging modality improved indexing insight interest language impairment novel outcome prediction sex skills standard of care stroke incidence stroke outcome stroke patient stroke risk stroke survivor young adult

项目摘要

Project Summary/Abstract The Center for the Study of Aphasia Recovery (C-STAR, P50-DC014664) explores recovery from language impairments following stroke. We have expertise using brain imaging and behavioral measures to identify risk factors for recovery. Stroke is influenced by the climate, with increased incidence both in the summer months as well as in warmer regions such as the `Stroke Belt` of the United States. For the first time ever, this proposal will allow us to examine the relationship between climate and 1) patterns of brain injury (location and extent) in stroke, and 2) patterns of behavioral impairment following stroke, in both chronic and acute data. We will examine these questions using archival data from existing acute (N =1500) and chronic datasets (N = 260) that include demographic, behavioral and brain imaging data points. These data were collected in South Carolina, which is considered the ‘Buckle’ of the ‘Stroke Belt’, and which may serve as a bellwether for future global warming. Our planned analyses will provide novel insights into the overall health burden of summer strokes, which requires us to determine whether additional strokes observed in the summer months lead to long-term impairment or are associated with smaller injuries where symptoms resolve spontaneously. We will pursue two archival analyses to resolve these questions.

项目摘要/摘要失语症恢复研究中心（C-Star，P50-DC014664）探讨了语言的恢复中风后的障碍。我们有使用大脑成像和行为措施来识别风险的专业知识恢复因素。中风受气候的影响，夏季的事件增加以及在美国的温暖地区，例如美国的“中风腰带”。有史以来第一次提案将使我们能够检查气候和1）脑损伤模式（位置和在中风和2）中风后行为障碍的模式中，在慢性数据和急性数据中。我们将使用现有急性（n = 1500）和慢性数据集（n = 260）的档案数据检查这些问题其中包括人口统计学，行为和脑成像数据点。这些数据是在南部收集的卡罗来纳州，被认为是“卒中腰带”的“扣”，可以用作未来的领头羊全球暖化。我们计划的分析将为夏季整体健康燃烧提供新颖的见解中风，这要求我们确定在夏季观察到的其他笔触是否导致长期损害或与较小的伤害有关，症状解决赞助。我们将进行两个档案分析以解决这些问题。