AppalTRuST Project 3: Impact of proposed tobacco product rules in Appalachia on consumption and product switching with the Experimental Tobacco Marketplace

AppalTRuST 项目 3：阿巴拉契亚拟议烟草产品规则对实验烟草市场消费和产品转换的影响

• 批准号: 10665322
• 负责人: Mikhail Nikolaas Koffarnus
• 金额: $ 65.24万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10665322
• 关键词: Appalachian Region; Authorization documentation; Behavior; Biometry; Catchment Area; Cigarette; Cities; Communities; Community Outreach; Complex; Consumption; Data; Economics; Elasticity; Environment; Goals; Grant; Informatics; Manufacturer; Measures; Menthol; Methods; Modeling; Nicotine; Participant; Pattern; Policies; Price; Public Health; Randomized; Recommendation; Regulation; Research; Rural; Rural Appalachia; Rural Community; Sampling; Taxation; Tobacco; Tobacco use; United States Food and Drug Administration; Variant; abuse liability; authority; behavioral economics; combustible cigarette; design; falls; low nicotine content cigarette; nicotine user; patient engagement; peri-urban; prospective; recruit; rural area; rural underserved; rurality; tobacco products; tobacco regulation; tobacco regulatory science; urban area

ABSTRACT – Project 3 Our overall goal, reflecting AppalTRuST’s Integrative Theme of investigating the effects of regulatory changes on tobacco product use in Appalachian KY, is to assess the impact of proposed tobacco product regulations using behavioral economic methods that we have developed and refined in past years to characterize the consumption of tobacco products within the complex nicotine marketplace of Appalachian KY, a diverse and underserved rural region that would greatly benefit from focused tobacco regulatory science research. This project primarily falls under the Regulatory Scientific Domain of Impact Analysis. In 2009, the Food and Drug Administration (FDA) was granted authority to regulate tobacco products to benefit public health. In the years since, the FDA has proposed potential regulatory actions that may benefit public health, including regulating the maximum nicotine content in combustible cigarettes and restricting flavors of combusted and non- combusted tobacco products. Estimating the impact of any proposed regulatory action is complicated by the existence of a complex tobacco marketplace containing multiple products that are economic substitutes for one another and the frequent introduction of new tobacco products by manufacturers. Furthermore, when compared to more urban, non-Appalachian communities, rural Appalachian communities often have 1) higher rates of tobacco product use overall, 2) different use patterns that include more combusted tobacco products, and 3) different product availability in tobacco stores. It is therefore important to estimate any differential impact of proposed tobacco-product regulations in Appalachia. Using an Experimental Tobacco Marketplace (ETM) model where product availability is manipulated across groups and demand elasticity and substitution is measured across tobacco products, we will estimate the impact of regulating 1) nicotine content of combusted cigarettes, 2) menthol flavor restrictions in combustible cigarettes, and 3) flavor additive restrictions in non- combusted nicotine/tobacco products including ENDS. Across two aims, we will assess the impact of these three regulations within Appalachia (Aim 1) and the effect of rurality on impact of these proposed regulations in Appalachia (Aim 2).

摘要 - 项目3 我们的总体目标，反映了AppalTrust调查监管变化效果的综合主题 关于阿巴拉契亚肯塔基州的烟草产品的使用是为了评估Produck产品法规的影响 使用我们在过去的Youars中开发和完善的行为经济方法来表征您 在复杂的阿巴拉契亚肯塔基州尼古丁市场中消费烟草产品，多元化 服务不足的Rual Al地区将受益于重点的烟草规则科学研究。 项目主要属于影响分析的监管科学领域。 行政管理（FDA）被授予监管烟草产品以使公共卫生受益。 从那以后，FDA支持了可能受益于公共卫生的潜在调节措施 燃烧香烟中的最大尼古丁含量以及燃烧和非燃烧的口味 燃烧的烟草产品。 存在一个复杂的烟草市场，其中包含多种产品，这是一个经济替代品 另一种是制造商的新型烟草产品 与更多城市，非阿帕拉奇社区相比，阿巴拉契亚农村社区通常具有1）更高 烟草产品的使用率总体上使用，2）不同的使用模式，包括更多coldustacco产品， 3）烟草存储中的不同产品可用性。 阿巴拉契亚州的托娃娃产物法规。 在跨越产品可用性以及需求弹性和变电站的模型是 通过烟草产品测量，我们将估计调节的影响1）燃烧的尼古丁含量 香烟，2）可燃香烟中的薄荷风味限制，3）非 - 燃烧的尼古丁/烟草产品包括两个目标。 阿巴拉契亚州内的三项法规（AIM 1）以及乡村对拟议法规影响的影响 阿巴拉契亚（AIM 2）。