Remote Alcohol Monitoring to Facilitate Abstinence Reinforcement: Feasibility

远程酒精监测以促进戒酒强化：可行性

• 批准号: 8771552
• 负责人: Mikhail Nikolaas Koffarnus
• 金额: $ 23.76万
• 依托单位: VIRGINIA POLYTECHNIC INST AND ST UNIV
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-05 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8771552
• 关键词: Abstinence; Accounting; Adult; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcohols; Biochemical; Cells; Cellular Phone; Deposition; Development; Dimensions; Disease; Drug abuse; Evidence based treatment; Feasibility Studies; Future; Incentives; Individual; Internet; Intervention; Knowledge; Location; Low income; Measurement; Measures; Methodology; Monitor; Participant; Patients; Persons; Phase; Population; Procedures; Psychological reinforcement; Publishing; Randomized; Reporting; Research; Rural; Sampling; Secure; Techniques; Technology; Time; Travel; United States; alcohol abstinence; alcohol content; alcohol craving; alcohol monitoring; contingency management; cost; detector; effective therapy; follow-up; interest; meetings; monitoring device; new technology; novel; payment; prevent; programs; public health relevance; reduced alcohol use; tool

DESCRIPTION (provided by applicant): Nearly 18% of United States adults meet criteria for alcohol dependence sometime in their lifetime, with only 24% of those individuals ever receiving any treatment for their disorder. The pervasiveness of alcohol dependence indicates a need for continued development of high-impact treatments that are both effective and easily disseminated to a broad population. Contingency management, or the delivery of monetary incentives contingent on verified abstinence, is an effective treatment for drug and alcohol abuse. However, technological barriers to accurate, frequent biochemical verification of alcohol abstinence limit the use of this technique for the treatment of alcohol dependence. Recently, a breathalyzer has been developed with technological features that make it ideally suited for use in a contingency management intervention. This breathalyzer has the capacity to remotely verify abstinence from alcohol and contains a number of features to verify the identity of the user and prevent tampering. In the present application, we propose to use this breathalyzer to facilitate a contingency-management intervention to reduce alcohol use that requires no in-person contact between the participants and the study staff during the intervention phase. To this end, we propose two specific aims. First, we will determine the feasibility of remotely-delivered contingency management trial to reduce alcohol use by using technological advances to overcome barriers in treatment delivery. We will conduct a randomized, controlled two-group feasibility study with a Contingent and Noncontingent group. The Contingent group will receive nearly immediate monetary payments over the internet each day they remotely provide negative breathalyzer samples. The Noncontingent group will receive payments each day they successfully provide samples independent of the alcohol content of those samples. Our first Specific Aim is to determine whether the contingency management intervention reduces alcohol use in the Contingent group to a greater extent than the Noncontingent group. In our second Specific Aim, we will assess participant ratings of acceptability and usefulness of these novel technologies. Poor ratings of acceptability or usefulness may suggest challenges of compliance and further dissemination. As potential treatment vehicles, it is important to assess whether the various technological tools and procedures used in this feasibility trial are viewed as effective and acceptable among individuals who are interested in reducing or ceasing their alcohol use. Together these specific aims will allow us to determine if remote, verified alcohol monitoring combined with nearly immediate, remote delivery of contingent monetary incentives is an effective treatment for alcohol dependence that is well accepted by participants.

描述（由申请人提供）：近 18% 的美国成年人在其一生中的某个时候符合酒精依赖标准，其中只有 24% 的人曾接受过任何针对其疾病的治疗。酒精依赖的普遍存在表明需要继续开发高效且易于向广大人群传播的治疗方法。应急管理，或根据经核实的戒酒情况提供金钱奖励，是治疗吸毒和酗酒的有效方法。然而，准确、频繁的戒酒生化验证的技术障碍限制了该技术用于治疗酒精依赖的使用。最近，开发了一种呼吸分析仪，其技术特点使其非常适合用于应急管理干预。该呼气分析仪能够远程验证戒酒情况，并包含许多功能来验证用户的身份并防止篡改。在本申请中，我们建议使用这种呼气分析仪来促进应急管理干预，以减少饮酒，在干预阶段，参与者和研究人员之间不需要面对面的接触。为此，我们提出两个具体目标。首先，我们将确定远程应急管理试验的可行性，通过利用技术进步克服治疗提供中的障碍来减少饮酒。我们将进行一项随机、对照的两组可行性研究，其中包括偶然组和非偶然组。每天，特遣队远程提供呼气分析仪阴性样本时，他们将通过互联网几乎立即收到金钱付款。非偶然组每天成功提供样品后都会收到付款，无论这些样品的酒精含量如何。我们的第一个具体目标是确定应急管理干预措施是否比非应急组更大程度地减少了应急组的饮酒量。在我们的第二个具体目标中，我们将评估参与者对这些新技术的可接受性和有用性的评级。可接受性或有用性的评级较差可能表明合规性和进一步传播面临挑战。作为潜在的治疗工具，重要的是要评估本次可行性试验中使用的各种技术工具和程序是否被认为对减少或停止饮酒感兴趣的个人有效且可接受。这些具体目标将使我们能够确定远程、经过验证的酒精监测与近乎即时、远程的或有金钱激励措施相结合是否是一种被参与者广泛接受的酒精依赖的有效治疗方法。