Administrative Core

行政核心

• 批准号: 10663080
• 负责人: GREGORY E. SIMON
• 金额: $ 69.73万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10663080
• 关键词: Address; Advisory Committees; Antipsychotic Agents; Clinical; Clinical Research; Collaborations; Communication; Communication Tools; Data; Evaluation; Family; Funding; Goals; Health Services Research; Health system; Infrastructure Activities; Integrated Health Care Systems; Lead; Learning; Libraries; Machine Learning; Mental Depression; Mental Health; Mental Health Services; Methods; National Institute of Mental Health; Network Infrastructure; Network-based; Observational epidemiology; Occupational activity of managing finances; Organization administrative structures; Patients; Pilot Projects; Practice based research; Primary Care; Process; Qualitative Research; Quality Control; Reaction Time; Request for Applications; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Resource Allocation; Resource Sharing; Resources; Site; Software Tools; Specific qualifier value; Speed; Strategic Planning; Structure; Suicide prevention; Trust; Youth; computable phenotypes; data infrastructure; first episode psychosis; health care delivery; implementation science; improved; large scale data; member; next generation; open source library; operation; outreach; patient engagement; patient population; practice-based research network; pragmatic trial; programs; response; success

We propose to expand the existing Mental Health Research Network (MHRN) to include 14 research centers embedded in large health systems serving over 25 million patients in 16 states. Existing MHRN infrastructure will be enhanced to support a next-generation practice-based network, including: • Increased engagement of patients, health system leaders, and other stakeholders in network governance and selection of research priorities • An expanded public, open-source library of software tools and other technical resources • More formal processes for conducting feasibility pilot projects and rapid response to stakeholder queries • Expanded outreach to external stakeholders and research partners This overall application requests support for an Administrative Core, a Methods core, two Signature research projects and two Pilot research projects. The Administrative Core, led by Gregory Simon and Belinda Operskalski, will include an Organizational Unit responsible for governance, strategic planning, fiscal management, and compliance; an Outreach and External Collaboration Unit responsible for communications, resource sharing, promoting new collaborations, and supporting feasibility pilot projects; and an Emerging Issues Unit to identify and address emerging questions for internal and external stakeholders. The Organizational Unit will maintain and enhance the governance, operational, fiscal management, and compliance resources proven successful in 8 years of MHRN operations. At each site, core resources will support effort by a site lead investigator (responsible for supervising local data infrastructure activities and health system engagement), one or more programmer/analysts (responsible for data infrastructure quality control, routine descriptive analyses, and analyses regarding emerging issues), and one or more project managers (responsible for local financial management and regulatory compliance). In the proposed new funding cycle, patient and family stakeholders will join the network Steering Committee and an External Advisory Committee will participate in network strategic planning and evaluation. The Outreach and External Collaboration unit will maintain and enhance the communications tools, resource sharing mechanisms, health system engagement processes, and external investigator engagement processes proven successful in 8 years of MHRN operation. A structured process for receiving and responding to requests for feasibility or pilot data (from either MHRN-based or external investigators) will include a transparent process for timely response to queries and specific resources allocated to small pilot projects. A structured process for receiving and responding to queries from health system and external stakeholders will include technical assistance to end- users and will draw from MHRN's large library of descriptive analyses, standard queries, and computable phenotypes.

我们建议扩大现有的心理健康研究网络 (MHRN)，将 14 个研究中心纳入其中 嵌入大型卫生系统，为 16 个州现有的 2500 万患者提供服务。 将得到增强以支持下一代基于实践的网络，包括： • 增加患者、卫生系统领导者和其他利益相关者对网络治理的参与 和研究重点的选择 • 扩展的公共开源软件工具和其他技术资源库 • 开展可行性试点项目和快速响应利益相关者询问的更正式流程 • 扩大与外部利益相关者和研究合作伙伴的联系 该整体应用程序请求支持管理核心、方法核心、两个签名研究 项目和两个试点研究项目，由格雷戈里·西蒙和贝琳达领导。 Operskalski 将包括一个组织单位，负责治理、战略规划、财务 管理和合规；负责沟通的外展和外部协作部门， 资源共享，促进新的合作，支持可行性试点项目； 问题部门确定并解决内部和外部利益相关者出现的问题。 组织单位将维持并加强治理、运营、财务管理和 在 MHRN 的 8 年运营中，合规资源已被证明是成功的 在每个站点，核心资源都将得到验证。 现场首席调查员的支持工作（负责监督本地数据基础设施活动和 卫生系统参与），一名或多名程序员/分析师（负责数据基础设施质量 控制、常规描述性分析以及有关新出现问题的分析）以及一个或多个项目 经理（负责当地财务管理和监管合规）。 资金周期，患者和家庭利益相关者将加入网络指导委员会和外部 咨询委员会将参与网络战略规划和评估。 合作单位将维护和加强通信工具、资源共享机制、卫生 系统参与流程和外部调查员参与流程在 8 年内被证明是成功的 MHRN 操作的结构化流程，用于接收和响应可行性或试点数据的请求。 （来自 MHRN 或外部调查人员）将包括一个及时响应的透明流程 查询和分配给小型试点项目的特定资源 接收和分配的结构化流程。 回应卫生系统和外部利益攸关方的询问将包括为最终目的提供技术援助： 用户并将从 MHRN 的大型描述性分析、标准查询和可计算库中获取信息 表型。