Biotechnology Training Program in Applied Life Sciences

应用生命科学生物技术培训计划

基本信息

批准号：
10649674
负责人：
Jeanne Ann Hardy
金额：
$ 53.05万
依托单位：
UNIVERSITY OF MASSACHUSETTS AMHERST
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10649674
关键词：
Biological Sciences Biotechnology Training Programs

项目摘要

Project Summary The past five years have been transformative for the Applied Life Sciences at the University of Massachusetts, Amherst (UMass). During this period a $95M investment in state-of-the art equipment housed in 30 core facilities operated by PhD-level center directors and over $400M in new research buildings has revolutionized the research capacity at our institution. This massive infrastructure growth has been matched with the hiring of over 50 new faculty in the life sciences. During this tremendous expansion we have developed the Biotech Training Program (BTP) in Applied Life Sciences, which leverages campus investments to provide outstanding training to a talented group of graduate students to prepare them for careers in the Biotech workforce and related areas. This training is guided by these objectives: 1) create a scholarly and social environment to facilitate new and strengthen existing interdisciplinary networks at UMass, particularly those at the interface of engineering and the life sciences; 2) educate students in the fundamentals of quantitative biotechnology through lecture and laboratory courses; 3) train students in the commercial impact of biotechnology through a tailored industrial internship and regular interactions with industrial personnel; 4) provide students with opportunities to improve interdisciplinary communication, expand career opportunities, and sharpen professional skills; and 5) increase the number of students, particularly those from underrepresented groups, who pursue careers in biotechnology. BTP faculty are recruited not by departmental affiliation, but by membership in the Institute for Applied Life Sciences (IALS), their research in biotechnology and their commitment to student training. For this reason, the UMass BTP recruits students from ten PhD programs: Biomedical Engineering, Chemical Engineering, Chemistry, Civil Engineering, Mechanical Engineering, Microbiology, Molecular & Cell Biology, Polymer Science & Engineering and Veterinary & Animal Sciences. We request ten Trainee slots (matched with three and a half slots annually from UMass). Traineeships are awarded to students for the 2nd and 3rd years of study during which students complete the BTP curriculum. Innovative features include the Frontiers in Biotechnology course that is co-taught by industry personnel; specialized Laboratory Modules in biotechnology-relevant techniques modeled after professional industry workshops; student-run Journal Club to break down discipline barriers; a new course in Quantitative Biology, Biostatistics & Data Science to promote modern data analysis fluency for all trainees; leadership in campus recruiting efforts for a diverse student population and accessibility to disabled students; an annual Fall Symposium in Biotechnology that offers a unique Biotech Battles experience where students solve real-world problems guided by industry experts; and targeted partnering with the UMass Office of Professional Development to provide career exploration and planning for our students. We have established numerous industrial partnerships to support the hallmark of our BTP, a formal internship in which all Trainees participate. Together this comprehensive training program prepares students well for a variety of careers in biotechnology.

项目摘要过去五年来，马萨诸塞大学应用生命科学的变革性是如此阿默斯特（UMass）。在此期间，在30个核心设施的最先进设备上进行了9500万美元的投资由博士级中心董事经营，新研究建筑的4亿美元超过4亿美元彻底改变了我们机构的研究能力。这种庞大的基础设施增长与雇用过度相匹配 50名生活科学的新教师。在这一巨大扩展期间，我们开发了生物技术培训应用生命科学的计划（BTP），利用校园投资提供出色的培训对于一群才华横溢的研究生，为生物技术劳动力和相关领域的职业做好准备。该培训以这些目标为指导：1）创建一个学术和社会环境，以促进新的和加强UMass现有的跨学科网络，尤其是在工程和工程界面的跨学科网络生命科学； 2）通过讲座和实验室课程； 3）通过量身定制的工业培训学生对生物技术的商业影响实习和与工业人员的定期互动； 4）为学生提供改进的机会跨学科的沟通，扩大职业机会并提高专业技能； 5）增加从事生物技术职业的学生人数，特别是来自代表性不足的群体的学生人数。 BTP教师不是通过部门隶属关系来招募的，而是通过申请研究所的成员资格生命科学（IALS），他们在生物技术方面的研究及其对学生培训的承诺。为此原因， UMass BTP从十个博士学位课程中招募学生：生物医学工程，化学工程，化学，土木工程，机械工程，微生物学，分子和细胞生物学，聚合物科学＆工程与兽医和动物科学。我们要求十个学员老虎机（与三个半匹配每年从UMass）。在第二年和第三年的学习中，授予了培训。学生完成BTP课程。创新功能包括生物技术课程的前沿，即由行业人员共同教授；与生物技术相关技术的专业实验室模块建模在专业行业讲习班之后；学生经营的期刊俱乐部分解纪律障碍；一门新课程在定量生物学，生物统计学和数据科学方面，以促进所有受训者的现代数据分析流利程度；在校园中的领导地位招募了各种学生人口的努力以及对残疾学生的可及性；一个每年的生物技术秋季研讨会，提供独特的生物技术战体体验，学生可以解决由行业专家指导的现实世界问题；并有针对性与UMass专业办公室合作开发为我们的学生提供职业探索和计划。我们已经建立了许多工业合作伙伴关系支持我们的BTP的标志，这是所有受训者参与的正式实习。这项全面的培训计划共同为学生做好了为生物技术职业提供的很好的准备。

项目成果

期刊论文数量（59）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The Zebrafish (Danio rerio) Embryo Model as a Tool to Assess Drinking Water Treatment Efficacy for Freshwater Impacted by Crude Oil Spill.

DOI：
10.1002/etc.5472
发表时间：
2022-11
期刊：
Environmental toxicology and chemistry
影响因子：
4.1
作者：
Roy MA;Mohan A;Karasik Y;Tobiason JE;Reckhow DA;Timme-Laragy AR
通讯作者：
Timme-Laragy AR

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons.

DOI：
10.1016/j.isci.2022.105187
发表时间：
2022-10-21
期刊：
ISCIENCE
影响因子：
5.8
作者：
McSweeney, Danny;Gabriel, Rafael;Jin, Kang;Pang, Zhiping P.;Aronow, Bruce;Pak, ChangHui
通讯作者：
Pak, ChangHui

Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids.

DOI：
10.1038/s41467-023-39420-6
发表时间：
2023-06-24
期刊：
NATURE COMMUNICATIONS
影响因子：
16.6
作者：
Sebastian, Rebecca;Jin, Kang;Pavon, Narciso;Bansal, Ruby;Potter, Andrew;Song, Yoonjae;Babu, Juliana;Gabriel, Rafael;Sun, Yubing;Aronow, Bruce;Pak, ChangHui
通讯作者：
Pak, ChangHui

Genetic circuits for feedback control of gamma-aminobutyric acid biosynthesis in probiotic Escherichia coli Nissle 1917.

用于反馈控制益生菌大肠杆菌 Nissle 中 γ-氨基丁酸生物合成的遗传电路 1917。