Cellular Engineering Biotechnology Training Program

细胞工程生物技术培训项目

• 批准号: 9306873
• 负责人: Jeanne Ann Hardy
• 金额: $ 17.81万
• 依托单位: UNIVERSITY OF MASSACHUSETTS AMHERST
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9306873
• 关键词: Biotechnology; Training Programs; cellular engineering; Biotechnology; Training Programs; cellular engineering

 DESCRIPTION (provided by applicant): Scientists and engineers at the University of Massachusetts, Amherst (UMA) are using state-of-the-art tools and approaches in cellular engineering to address key challenges in biotechnology for human health, including production of anti-cancer drugs from cell cultures, transformation of mammalian cells into useful tissues for organ replacement, and design of novel proteins to serve as advanced therapies. UMA has a history of strength in biotechnology, founding the Institute for Cellular Engineering (ICE) as a platform to sustain and develop novel research and training programs. Given the successful track record of ICE training programs, geographic proximity to a leading biotech hub in Boston, and strong institutional support for development of industry-academic collaborations, UMA is ideally positioned to develop an impactful Biotechnology Training Program (BTP). BTP objectives are to: 1) create a scholarly and social infrastructure to facilitate new and strengthen existing interdisciplinary networks at UMA, particularly those at the interface of engineering and the life sciences; 2) educate students in the fundamentals of quantitative biotechnology through new lecture and laboratory courses; 3) train students to appreciate the impact of biotechnology commercially through a tailored industrial internship and regular interactions with industrial personnel; 4) provide students with opportunities to improve interdisciplinary communication, expand career opportunities, and sharpen professional skills; and 5) increase the number of students, particularly those from URM groups, who pursue careers in biotechnology. This BTP will recruit matriculated predoctoral students from five programs (Chemical Engineering, Chemistry, Polymer Science & Engineering, Veterinary & Animal Sciences, Molecular and Cellular Biology). We request six Trainee slots (matched with two slots from UMA). Traineeships will be awarded to students in their 2nd and 3rd years of study, and we will offer an Associate membership for non-funded students to broaden the impact of the program. Students will complete a prescribed curriculum over two years and obtain a graduate certificate in Cellular Engineering. Innovative features include the Biotechnology Core Course that is informed by and co-taught by industry personnel; specialized Laboratory Modules in biotechnology-relevant approaches and techniques modeled after professional industry workshops; student-run Biotechnology Journal Club to break down discipline barriers in a non-threatening atmosphere; a newly designed course in Biostatistics and Statistical Computing to promote math fluency for all Trainees; collaboration with the STEM Diversity Institute to ensure a diverse student population; an annual Symposium on Biotechnology that offers a unique "Speed Dating" experience where students pitch their ideas and receive feedback from industry experts; and targeted partnering with the new UMA Graduate School Office of Professional Development to provide career exploration and planning for our students. We have recruited numerous industrial partners to support a hallmark of our program, a formal internship in which all Trainees will participate.

 描述（由适用提供）：马萨诸塞大学的科学家和工程师，阿默斯特（UMA）正在使用细胞工程中的最先进的工具和方法来应对生物技术在人类健康中的关键挑战，包括从细胞培养物中生产抗癌药物，从细胞中产生抗癌药物，将哺乳动物细胞转化为有用的组织，以替代蛋白质的蛋白质和设计蛋白质，并作为新颖的蛋白质替代。乌玛（Uma）具有生物技术的力量历史，创立了蜂窝工程研究所（ICE），作为维持和开发新型研究和培训计划的平台。鉴于冰训练计划的成功记录，与波士顿领先的生物技术枢纽的地理距离以及对行业学术合作的发展的强烈机构支持，UMA非常适合开发有影响力的生物技术培训计划（BTP）。 BTP目标是：1）创建一个科学和社会基础设施，以促进新的并加强 UMA的现有跨学科网络，尤其是在工程和生命科学界面的跨学科网络； 2）通过新的讲座和实验室课程的定量生物技术基础教育学生； 3）培训学生通过量身定制的工业实习和与工业人员的定期互动在商业上欣赏生物技术的影响； 4）为学生提供改善跨学科沟通，扩大职业机会并提高专业技能的机会； 5）增加了在生物技术领域购买职业的URM群体的学生人数，尤其是来自URM群体的学生人数。该BTP将招募来自五个计划（化学工程，化学，聚合物科学与工程，兽医和动物科学，分子和细胞生物学）的实质性前学生。我们要求六个实习生插槽（与UMA的两个插槽匹配）。在第二年和第三年学习的学生将获得培训，我们将为非资助的学生提供助理会员资格，以扩大该计划的影响。学生将在两年内完成规定的课程，并获得蜂窝工程的研究生证书。创新的功能包括由行业人员告知和共同教授的生物技术核心课程；在专业行业讲习班以生物技术与生物技术相关的方法和技术中的专业实验室模块；学生经营的生物技术期刊俱乐部，以在不威胁的氛围中打破纪律障碍；新设计的生物统计学和统计计算课程，可促进所有学员的数学流畅性；与STEM多样性研究所合作，以确保潜水员的学生人数；一年一度的生物技术研讨会，提供独特的“速度”约会“体验”体验，学生们提出想法并收到行业专家的反馈；与新的UMA专业发展院专业发展办公室合作，为学生提供职业探索和计划。我们招募了众多工业伙伴，以支持我们计划的众多计划，以支持我们的正式实习，所有受训者都将参与所有受训者。