Physician-Scientist Training in Emerging Infectious Diseases

新发传染病的医师科学家培训

• 批准号: 10647762
• 负责人: Peter C. Melby
• 金额: $ 18.68万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-22 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10647762
• 关键词: Emerging Communicable Diseases; Physicians; Scientist; Training

PROJECT SUMMARY/ABSTRACT This new Institutional Training Grant (T32) application from the University of Texas Medical Branch (UTMB) will provide multidisciplinary and interprofessional research training for physician-scientists in emerging infectious diseases (EIDs). The ongoing risk and likelihood of facing outbreaks and epidemics caused by EIDs highlights a critical need for developing physician-scientists with trans-disciplinary skills in clinical medicine, epidemiology, field investigation, laboratory science, and biocontainment. The program capitalizes on world- class faculty expertise, longstanding institutional commitments, and unique research resources. It includes targeted recruitment of candidates at local, regional and national levels. Candidates will be physicians who are completing or have completed, an ACGME-certified residency or fellowship. One trainee per year will enter and complete 2-3 years of training during the 5-year program. Training includes instruction and mentorship in 1) team science; 2) research design, epidemiological methods, and biostatistics (MSc in Clinical Science); 3) EIDs and outbreak investigation; 4) clinical and research biocontainment/biosafety; 5) responsible conduct of research; 6) field epidemiology; and 7) scientific writing. Each of the trainees will apply their training by conducting translational research while receiving intensive scientific and career mentorship through a novel Team Science framework called individualized Multidisciplinary, Interprofessional Mentorship Team (iMIMT). Each iMIMT will include the trainee, a primary and secondary mentor (a PhD scientist and a MD scientist), and 2 or 3 peer or specialized knowledge mentors. iMIMTs will receive regular Team Science training and coaching. Instruction in grant writing will culminate in submission of an NIH career development application in the last year of training. Regular, but limited clinical responsibility will enable trainees to maintain clinical skills and learn how to manage a dual clinical-research career. Our 29 program faculty have productive translational research programs in EIDs and a record of successful mentoring. They are complemented by collaborating investigators from Peru, Colombia, Mexico, Dominican Republic, and Brazil. Additional program support faculty have specialized expertise for programmatic/operational support. The trainees' individualized development plan includes well-defined training activities, expected competencies, indicators of success, and a timeline for completion. Co-Program Directors and 3 Associate Program Directors will lead the program under Steering Committee governance. Sub-committees will oversee trainees' recruitment and selection, mentorship, and scientific progress. An External Advisory Committee will evaluate the program's progress annually. At completion, our trainees will have strong trans-disciplinary understanding of EIDs, will be grounded in research methods and outbreak investigation, will have tools for collaborative problem-solving, and critical skills in manuscript and grant writing. All of these will facilitate their transition to an independent physician-scientist.

项目摘要/摘要 得克萨斯大学医学分公司（UTMB）的这项新的机构培训补助金（T32）申请将 为新兴的传染性医师提供多学科和跨专业研究培训 疾病（开斋节）。持续的风险和面对爆发和由EID引起的流行病的可能性突出显示 培养具有跨学科技能的临床医学技能的医师科学家的迫切需求， 流行病学，现场调查，实验室科学和生物内在。该计划大写了世界 - 班级教师专业知识，长期的机构承诺和独特的研究资源。它包括 在地方，地区和国家一级招募候选人。候选人将是医生 完成或已完成ACGME认证的居住或奖学金。每年一名学员将进入， 在5年计划中完成2 - 3年的培训。培训包括1中的指导和指导 团队科学； 2）研究设计，流行病学方法和生物统计学（临床科学的MSC）； 3） 开斋节和爆发调查； 4）临床和研究生物内在/生物安全； 5）负责任的行为 研究; 6）田间流行病学； 7）科学写作。每个学员将通过 通过一部小说进行强化科学和职业指导，进行翻译研究 团队科学框架称为个性化多学科，跨专业指导团队（IMIMT）。 每个IMIMT都将包括学员，主要和次级导师（博士学位科学家和医学博士科学家），以及 2或3个同伴或专业知识导师。 Imimts将接受定期的团队科学培训，并 教练。赠款写作中的指示将在提交NIH职业发展申请中最终 培训的最后一年。常规但有限的临床责任将使学员能够保持临床技能 并了解如何管理双重临床研究职业。我们的29个课程教师具有富有成效的翻译 开斋节的研究计划和成功指导的记录。他们通过合作而得到补充 来自秘鲁，哥伦比亚，墨西哥，多米尼加共和国和巴西的调查人员。额外的计划支持教师 具有专业的专业知识，可用于程序化/运营支持。学员的个性化发展 计划包括定义明确的培训活动，预期能力，成功指标以及时间表 完成。副总监和3名副计划主管将领导该计划在转向下 委员会治理。小组委员会将监督学员的招聘和选择，指导和 科学进步。外部咨询委员会将每年评估该计划的进度。在 完成，我们的学员将对开斋节有深刻的跨学科理解，将基于研究 方法和爆发调查将拥有协作解决问题的工具，以及关键技能 手稿和赠款写作。所有这些都将促进他们向独立医师科学家的过渡。

项目成果

Pathophysiology, Diagnosis, and Management of Chronic Spontaneous Urticaria: A Literature Review.

慢性自发性荨麻疹的病理生理学、诊断和治疗：文献综述。

• DOI: 10.1007/s12016-022-08952-y
• 发表时间: 2022
• 期刊: Clinical reviews in allergy & immunology
• 影响因子: 9.1
• 作者: Greiner,Benjamin;Nicks,Savannah;Adame,Michael;McCracken,Jennifer
• 通讯作者: McCracken,Jennifer

Asthma-related disparities in emergency department use and clinical outcomes among Spanish-speaking Hispanic patients.

讲西班牙语的西班牙裔患者在急诊科使用和临床结果方面与哮喘相关的差异。

• DOI: 10.1016/j.anai.2022.11.002
• 发表时间: 2023
• 期刊: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
• 作者: Greiner,Benjamin;Cronin,Kelly;Salazar,Leonardo;Hartwell,Micah
• 通讯作者: Hartwell,Micah

Influenza Vaccination Uptake Trends by Age, Race, and Ethnicity in the United States Between 2017 and 2020.

• DOI: 10.1177/21501319221104917
• 发表时间: 2022-01
• 期刊: JOURNAL OF PRIMARY CARE AND COMMUNITY HEALTH
• 影响因子: 3.6
• 作者: Greiner, Benjamin;Hartwell, Micah
• 通讯作者: Hartwell, Micah