Human Subjects Core

人类受试者核心

基本信息

批准号：
10647726
负责人：
Patricia Ann Shi
金额：
$ 46.07万
依托单位：
NEW YORK BLOOD CENTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-20 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10647726
关键词：
Acute Benign Biological Blood Characteristics Clinical Clinical Data Code Collaborations Collection Communication Complex Computer software Consent Data Data Analyses Databases Drops Eligibility Determination Enrollment Ensure Floor Freezing Future Hematologist Hematology Hemoglobinopathies Hemolysis Human Resources Infrastructure Institution Laboratories Logistics New York Notification Patient Care Patient Recruitments Patients Persons Physicians Positioning Attribute Quality Control Research Research Activity Research Personnel Research Project Grants Sampling Schedule Sickle Cell Anemia Specialist Specimen Study Subject Time Transfusion Update Work biobank central database clinical application clinical development clinical material clinical research site clinically relevant cloud based experience human subject insight interest meetings mouse model participant enrollment programs sample collection transfusion medicine videoconference

项目摘要

Summary / Abstract The Human Subjects Core B, physically located at the New York Blood Center, will have a centralized function of 1) optimizing collection of high quality biologic specimens and clinical data to support the proposed studies in the four projects described in this PPG application , and 2) providing clinically-based insights and analysis to the laboratory-based investigators on their research projects. The Core will be the primary contact with the institutional co-investigators to maximize the work efficiency. The aims of the Core include to ensure the timely and proper collection, transport, distribution, storage, and tracking of high-quality research samples through use of an centralized cloud-based database and weekly meetings with the clinical and lab investigators (Aim1); to establish and actively maintain the centralized database of high-quality human subject clinical information to ensure timely and accurate correlation and annotation of clinical variables to laboratory analyses (Aim 2) and to provide clinical expertise and insight in both benign hematology and transfusion medicine to the laboratory-based investigators on their research projects and laboratory data interpretation (Aim 3). Provision of such critical clinical material together with the clinical expertise of the Core will facilitate and enhance the clinical applicability of the findings emerging from this Program Project.

摘要 /摘要人类受试者核心B物理位于纽约血液中心，将具有集中功能 1）优化高质量生物标本和临床数据的收集，以支持拟议的研究本PPG应用中描述的四个项目以及2）为临床上的见解和分析提供基于实验室的研究人员的研究项目。核心将是与机构共同投资者，以最大化工作效率。核心的目的包括确保及时以及通过使用的适当收集，运输，分配，存储和跟踪高质量研究样本与临床和实验室调查人员的基于云的集中数据库以及每周的会议（AIM1）；到建立并积极维护高质量人类主题临床信息的集中数据库确保临床变量与实验室分析的及时，准确的相关性和注释（AIM 2）和向基于实验室的良性血液学和输血医学提供临床专业知识和见解研究人员的研究项目和实验室数据解释（AIM 3）。提供这样的批判性临床材料以及核心的临床专业知识将促进和增强临床适用性该计划项目的发现。