SCGE Administrative Supplement

SCGE行政补充

• 批准号: 10651526
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 18.74万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-27 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10651526
• 关键词: Address; Administrative Supplement; California; Center for Translational Science Activities; Clinical Sciences; Collaborations; Communities; Ensure; Equipment; Evaluation; Fostering; Future; Genome; Infrastructure; Primates; Research; Research Personnel; Resources; Service provision; Technology; Testing; Translations; genome editing; human disease; nonhuman primate; somatic cell gene editing; support tools; synergism; tool

PROJECT SUMMARY / ABSTRACT The Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools supports studies with nonhuman primates that will advance the genome editing field, and significantly contributes to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center includes a robust team and partnerships that capitalize on major strengths including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center offers state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) awardees to conduct high quality research in nonhuman primates. The Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Testing Center fosters partnerships with SCGE awardees through provision of expertise, resources, and collaborative opportunities that accelerate their research, and ensures synergism across the SCGE Consortium and with ongoing interactions with the Dissemination and Coordinating Center. This supplement provides equipment that addresses the basic functions of the Testing Center and the provision of services to investigators across the SCGE Consortium.

项目摘要 /摘要 躯体细胞基因组编辑工具评估的非人类灵长类动物测试中心支持研究 有了非人类灵长类动物，将推进基因组编辑领域，并为未来做出重大贡献 这些技术治疗人类疾病的翻译。非人类灵长类动物测试中心 包括一个强大的团队和合作伙伴关系，利用包括加利福尼亚国家在内的主要优势 灵长类动物研究中心，基因组中心以及临床和转化科学中心。非人类 灵长类动物测试中心提供了躯体细胞基因组编辑（SCGE）获奖者的最先进功能 在非人类灵长类动物中进行高质量的研究。测试中心利用支持框架 这表明了为提供研究机会和合作的长期承诺 全国调查人员。通过这个强大的基础设施，测试中心建立了与 通过提供专业知识，资源和协作机会来加速他们的SCGE获奖者 研究，并确保整个SCGE财团的协同作用以及与 传播和协调中心。该补充提供了解决基本的设备 测试中心的功能以及向整个SCGE财团的调查人员提供服务。