Biomolecular Research Core

生物分子研究核心

• 批准号: 10640908
• 负责人: Kenneth A Cornell
• 金额: $ 57.35万
• 依托单位: BOISE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10640908
• 关键词: Area; Award; Biochemistry; Bioinformatics; Biological Sciences; Biology; Biomedical Engineering; Biomedical Research; Biometry; Businesses; Cell Nucleus; Centers of Research Excellence; Chemistry; Communities; Computer Analysis; Computer software; Core Facility; Data Analyses; Dedications; Discipline; Disease Progression; Education; Electrical Engineering; Engineering; Equipment; Experimental Designs; Extracellular Matrix; Fee-for-Service Plans; Fostering; Foundations; Funding; Future; Goals; Growth; Histology; Human Resources; Idaho; Image; Individual; Interdisciplinary Study; Laboratories; Maintenance; Manuscripts; Mass Spectrum Analysis; Medical center; Microscopy; Mission; Modeling; Natural regeneration; Peer Review; Peer Review Grants; Phase; Physics; Play; Production; Proteomics; Publishing; Recombinant Proteins; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Role; Running; Schools; Science; Senior Scientist; Service delivery model; Services; Students; Therapeutic; Time; Tissues; Training; United States National Institutes of Health; Universities; Veterans; Vision; Visualization; Work; career; college; cyber infrastructure; data acquisition; instrumentation; materials science; metabolomics; next generation sequencing; operation; programs; repaired; simulation; success; therapeutic development; tissue regeneration; tissue repair; transcriptomics

Project Summary – Biomolecular Research Core The overarching goal of the Biomolecular Research Core is to provide critical components of the research infrastructure needed for the success of our biomedical research programs. Access to instrumentation is essential in enabling Boise State University to build a research capability that will support researchers in their endeavor to carry out multidisciplinary research in the area on matrix biology. During COBRE Phase I, the Biomolecular Research Core supported 16 junior investigators within the COBRE in Matrix Biology as well as more established biomedical researchers. Five disciplines across campus are represented among the junior investigator projects including Biological Sciences, Chemistry & Biochemistry, Physics, Material Sciences, Electrical Engineering. Through the services offered to the research community by the BRC, we now have a much larger community of early and mid-career researchers, as well as investigators who have well- established research programs. The total number of annual users increased from 50 in 2014 to 119 in 2017, more than doubling in this time period. Investigators supported by the BRC published 78 peer-reviewed manuscripts that cite the BRC and the COBRE award, and they made more than 700 scientific presentations. The Core facility is equipped for histology, microscopy, and mass spectrometry for proteomics and metabolomics analysis. In partnership with the University of Idaho and Idaho State University, junior investigators will continue to have access to next-generation sequencing instrumentation and technical staff, which will allow them to combine transcriptomics with proteomics. The Core has enhanced current and future NIH-supported research and will continue to do so in Phase II. Establishing and operating the Core is integral to the Center of Biomedical Research Excellence in Matrix Biology and we will continue to work toward sustainable biomedical research growth at Boise State. This facility will be sustained through a business plan based on a fee-for-service model and partnership with departments, schools, and colleges within the university to assure that we are working toward a shared vision and common goals for biomedical research growth that are consistent with the mission of Boise State University.

项目摘要 - 生物分子研究核心 生物分子研究核心的总体目标是提供研究的关键组成部分 我们的生物医学研究计划成功所需的基础设施。获得仪器是 使博伊西州立大学能够建立研究能力，以支持研究人员 在基质生物学领域进行多学科研究的努力。在第一阶段， 生物分子研究核心支持基质生物学的毛刺中的16名初级研究者以及 更具成熟的生物医学研究人员。校园中的五个学科在大三中代表 研究人员项目，包括生物科学，化学和生物化学，物理，材料科学， 电气工程。通过BRC向研究社区提供的服务，我们现在有一个 早期和中期研究人员的更大社区以及具有很好的研究人员 建立的研究计划。年度用户总数从2014年的50个增加到2017年的119 在这段时间内增加了一倍以上。 BRC支持的调查人员已发表了78次同行评审 援引BRC和毛绒奖的手稿，他们进行了700多个科学演讲。 核心设施配备了组织学，显微镜和质谱，用于蛋白质组学和 代谢组学分析。与爱达荷大学和爱达荷州大学的初中合作 调查人员将继续使用下一代测序仪器和技术人员， 这将使他们能够将转录组学与蛋白质组学相结合。核心增强了当前和未来 NIH支持的研究将在第二阶段继续进行。建立和操作核心是不可或缺的 到基质生物学卓越生物医学研究中心，我们将继续努力 博伊西州的可持续生物医学研究增长。该设施将通过商业计划来维持 基于大学，学校和大学的收费模式以及与大学内部的学院和学院的合作伙伴关系 为了确保我们正在朝着共同的愿景和共同的生物医学研究增长目标， 与博伊西州立大学的任务一致。