Pro-Social Behavior and Neural Development during Adolescence

青春期的亲社会行为和神经发育

• 批准号: 10322404
• 负责人: Naomi Ilana Eisenberger
• 金额: $ 58.94万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-01-26 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10322404
• 关键词: Adolescence; Adolescent; Adolescent Behavior; Adult; Age; American; Attention; Behavior; Behavior Disorders; Behavioral; Brain; Child; Childhood; Cognition; Decision Making; Development; Elements; Emotions; Empathy; Ethnic Origin; Etiology; European; Family; Female; Financial Contribution; Financial Support; Friends; Functional Magnetic Resonance Imaging; Health; Health Benefit; Individual Differences; Knowledge; Latino; Link; Longitudinal Studies; Mediating; Mental Depression; Mental disorders; Participant; Pattern; Personal Satisfaction; Portraits; Process; Psyche structure; Psychologist; Psychopathology; Questionnaires; Reporting; Research; Resources; Rewards; Risk; Risk Behaviors; Role; Sampling; Scanning; Social Behavior; Social support; Stressful Event; Time; Work; adolescent brain development; boys; cardiovascular risk factor; cognitive ability; cognitive control; cognitive neuroscience; cohort; cost; diaries; experimental study; gender difference; girls; individual response; longitudinal design; mortality; neural correlate; neural network; neurobehavioral; neurodevelopment; peer; psychologic; relating to nervous system; social; social relationships; volunteer

Project Summary A large body of empirical work has focused on risky behavior and mental disorders during adolescence, but our knowledge of the neurobehavioral developments in prosocial behavior is quite limited. The result is a portrait of adolescent brain development that focuses risk and psychopathology over more positive behavior. This focus is unfortunate because several prosocial behaviors that involve giving to others – ranging from volunteering to providing instrumental or social assistance – have been linked to healthy psychological, behavioral, and physical profiles. Giving resources and assistance to others is associated with lower mortality, fewer objective and subjective health problems, and lower depression. The health benefits of giving to others warrant an increased focus on the neurobehavioral developments that underlie this core aspect of prosocial behavior during adolescence, a key point of development that sets the stage for lifelong health and well-being. We aim to advance the field by utilizing a longitudinal design to pursue four specific aims: (1) clarify developmental changes in prosocial behavior during adolescence by longitudinally examining a specific, fundamental prosocial behavior (i.e., giving) and how it increasingly depends upon the situation (i.e., the potential recipient, the cost of giving); (2) examine how neurodevelopment in the reward, mentalizing, and cognitive control neural networks tracks with giving behavior; (3) assess how social relationships, perspective- taking, empathy, and values may relate to giving and neural development; (4) explore potential gender differences in average levels of giving and neural processes. Using a cohort-sequential longitudinal design, a total of 180 participants will be assessed at three times, every two-years, across a five-year period. The total sample will consist of three overlapping age cohorts of 60 participants each and will cover the age span from 9 to 17 yrs. (Cohort 1: 9-13 yrs., Cohort 2: 11-15 yrs., Cohort 3: 13-17 yrs.). At each time point, participants will participate in an established decision-making task optimized for the fMRI scanner in which they will be asked to make real financial contributions to their families, friends, and a stranger under varying conditions of cost to themselves. While making decisions, participants' brains will be scanned for activation and functional connectivity between regions and networks that have been implicated in mentalizing, cognitive control, and reward-related behaviors. Adolescents also will complete questionnaires and daily diary checklists that will assess aspects of social relationships, perspective-taking, empathy, and values thought to predict prosocial behavior.

项目概要 大量的实证工作都集中在青春期的危险行为和精神障碍上，但是 我们对亲社会行为的神经行为发展的了解相当有限。 青少年大脑发育的肖像，重点关注风险和精神病理学而不是更积极的行为。 这种关注是不幸的，因为一些亲社会行为涉及给予他人——从 志愿提供工具或社会援助——与健康的心理、 向他人提供资源和帮助与较低的死亡率相关。 更少的客观和主观健康问题，以及更低的抑郁症 给予他人的健康益处。 需要更多地关注构成亲社会这一核心方面的神经行为发展 青春期的行为是发展的关键点，为终身健康和福祉奠定了基础。 我们的目标是利用纵向设计来推进该领域的发展，以实现四个具体目标：（1）澄清 通过纵向检查特定的、 基本的亲社会行为（即给予）以及它如何越来越取决于情况（即 (2) 检查奖励、心智化和行为方面的神经发育如何 认知控制神经网络跟踪给予行为；（3）评估社会关系、观点- (4)探索潜在性别 给予和神经过程的平均水平的差异。 采用队列序贯纵向设计，总共 180 名参与者将接受 3 次评估， 每两年一次，在五年期间内，总样本将由三个重叠的年龄组组成，每组年龄为 60 岁。 每个参与者的年龄跨度为 9 至 17 岁（第 1 组：9-13 岁，第 2 组：11-15 岁， 第 3 组：13-17 岁）在每个时间点，参与者将参与既定的决策任务。 针对功能磁共振成像扫描仪进行了优化，其中他们将被要求为其家庭做出真正的经济贡献， 朋友和陌生人在做出决定时，他们自己的成本不同。 大脑将被扫描以了解已被激活的区域和网络之间的激活和功能连接 涉及心理化、认知控制和奖励相关行为的青少年也会完成。 问卷和每日日记清单将评估社会关系、观点采择、 同理心，以及预测亲社会行为的价值观。

项目成果

Giving to others and neural processing during adolescence.

• DOI: 10.1016/j.dcn.2022.101128
• 发表时间: 2022-08
• 期刊: DEVELOPMENTAL COGNITIVE NEUROSCIENCE
• 影响因子: 4.7
• 作者: Karan, Maira;Lazar, Lee;Leschak, Carrianne J.;Galvan, Adriana;Eisenberger, Naomi I.;Uy, Jessica P.;Dieffenbach, Macrina C.;Crone, Eveline A.;Telzer, Eva H.;Fuligni, Andrew J.
• 通讯作者: Fuligni, Andrew J.

Sleep duration moderates the associations between immune markers and corticolimbic function during stress in adolescents.

睡眠持续时间调节青少年压力期间免疫标志物与皮质边缘功能之间的关联。

• DOI: 10.1016/j.neuropsychologia.2022.108374
• 发表时间: 2022
• 期刊: Neuropsychologia
• 影响因子: 2.6
• 作者: Uy,JessicaP;Dieffenbach,Macrina;Leschak,CarrianneJ;Eisenberger,NaomiI;Fuligni,AndrewJ;Galván,Adriana
• 通讯作者: Galván,Adriana

Is There Inequality in What Adolescents Can Give as Well as Receive?

• DOI: 10.1177/0963721420917738
• 发表时间: 2020-08-01
• 期刊: Current directions in psychological science
• 影响因子: 7.2
• 作者: Fuligni AJ

Corticostriatal Connectivity during Prosocial Decision-making Relates to Giving Behavior during Adolescence.

亲社会决策过程中的皮质纹状体连接与青春期的给予行为有关。

• DOI: 10.1162/jocn_a_02024
• 发表时间: 2023
• 期刊: Journal of cognitive neuroscience
• 影响因子: 3.2
• 作者: Uy,JessicaP;Fuligni,AndrewJ;Eisenberger,NaomiI;Crone,EvelineA;Telzer,EvaH;Galván,Adriana
• 通讯作者: Galván,Adriana