Emotion Regulation Interventions for Preventing Collegiate Escalations in Drinking: A Randomized Controlled Trial to Establish Acceptability, Feasibility and Preliminary Efficacy

防止大学饮酒升级的情绪调节干预措施：一项旨在确定可接受性、可行性和初步有效性的随机对照试验

基本信息

批准号：
10229549
负责人：
MICHAEL FENDRICH
金额：
$ 23.14万
依托单位：
UNIVERSITY OF CONNECTICUT STORRS
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-25 至 2023-08-31
项目状态：
已结题

项目摘要

In the most recent National Survey on Drug Use and Health (NSDUH; Lipari & Jean-Francois, 2016), college- aged respondents between 18 and 25 years old reported the highest alcohol use rates (over 58%) as well as the highest rates of binge drinking of any age group. High alcohol use/abuse in college students is associated with myriad negative consequences, including fatal and nonfatal injuries and overdoses, impaired academic and vocational performance, violence and other crime, legal problems, unintended pregnancies and sexually transmitted diseases, and social problems. The National Comorbidity Survey (NCS) underscores that use initiated in this period is not just experimental and recreational but may have lasting effects on consumption trajectories: For the majority of adults diagnosed alcohol use disorders, onset occurred during emerging adulthood. During this stage of development, vast changes in emotion regulation (ER) take place, particularly age-related shifts in the strategies used to manage distress that may lead to alcohol use/abuse (i.e., emotion suppression, inhibitory control, and cognitive reappraisal. Substantial evidence suggests that deficits in ER are strongly related to patterns of alcohol use in young adults. In particular, deficits in the self- regulation of discomfort and distress, called distress tolerance, predict alcohol use – specifically, motivation and urgency for use, escalations in consumption, and the development of dependence that may be indicative of alcohol use disorders. Emerging adults who turn to alcohol as a way of coping with distressing emotions are most at risk for heavy alcohol use into adulthood and more severe negative alcohol consequences. Given the variable effectiveness of existing approaches for reducing college students' alcohol use, we contend that interventions may be differentially effective depending on individual characteristics. In particular, students with difficulties in managing distress and discomfort may benefit from more intensive interventions that promote effective ER compared to treatment as usual; further, other background characteristics may predict the efficacy and acceptability of each type of ER intervention. In this R34 application (PA-18-775), we will test the acceptability/feasibility and preliminary efficacy of two complementary interventions (Yoga and Distress Tolerance) on preventing alcohol use in a randomized controlled trial of 180 high-risk college students relative to treatment as usual. We will assess participants' alcohol use (self-report and biomarker measures) and emotion regulation (ER) at baseline along with physiological discomfort sensitivity and psychosocial predictors of treatment efficacy over time, including a post-treatment follow-up. Our approach is innovative in examining the utility of different types of ER-oriented interventions for high risk young adults and includes innovative measurement components. The project is highly suited for the R34 mechanism to establish feasibility and preliminary efficacy. Aligned with the NIAAA strategic plan, we address the real-world complexities of substance use prevention by focusing on ER as the target mechanism for reductions in use.

在最近的全国药物使用与健康调查中（NSDUH； Lipari＆Jean-Francois，2016年）年龄在18至25岁之间的受访者报告说，酒精使用率最高（超过58％），以及任何年龄段的暴饮暴食率最高。大学生的大量酒精使用/滥用由于致命和非致命伤害和过量服药，包括无数的负面后果，学术障碍以及选民绩效，暴力和其他犯罪，法律问题，意外怀孕以及性传播疾病和社会问题。国家合并症调查（NCS）强调在此期间开始的使用不仅是实验性和娱乐性的，而且可能对消费轨迹：对于大多数成年人诊断出饮酒障碍，发作发生在新兴成年。在这一发展阶段，情绪调节（ER）的巨大变化，特别是与年龄相关的转变，用于管理可能导致饮酒/滥用的苦难的策略（即情绪抑制，抑制性控制和认知重新评估。大量证据表明， ER的缺陷与年轻人的饮酒模式密切相关。特别是在自我中定义调节不适和困扰，称为遇险容忍，预测饮酒 - 特别是动机以及使用的紧迫性，消费的升级以及依赖的发展可能是指示性的饮酒障碍。新兴的成年人转向酒精以应对令人痛苦的情绪的一种方式大多数人有大量饮酒的风险成年和更严重的负面饮酒后果。鉴于现有方法减少大学生的饮酒的可变有效性，我们联系了根据个人特征，这种干预措施可能在差异上有效。特别是学生在管理困扰和不适的情况下，可能会受益于更密集的干预措施与治疗相比，有效的ER；此外，其他背景特征可以预测有效性和每种类型的ER干预措施的可接受性。在此R34应用程序（PA-18-775）中，我们将测试两种完善干预措施的可接受性/可行性和初步效率（瑜伽和痛苦公差）在180名高风险大学生的随机对照试验中预防饮酒照常治疗。我们将评估参与者的饮酒（自我报告和生物标志物措施）和基线的情绪调节（ER）以及身体不适的敏感性和社会心理预测指标随着时间的流逝，包括治疗后的随访。我们的方法是创新的在检查不同类型的高风险年轻人的不同类型的ER导向干预措施时，包括创新的测量组件。该项目非常适合R34机制建立可行性和初步效率。与NIAAA战略计划保持一致，我们解决了现实世界通过专注于ER作为减少使用的目标机制，预防药物使用的复杂性。