Advanced-Stage Development of a Geriatric Palliative Care Research Infrastructure

老年姑息治疗研究基础设施的高级开发

基本信息

批准号：
10407003
负责人：
MELISSA Diane ALDRIDGE
金额：
$ 68.72万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2025-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10407003
关键词：
Academy Address Aging Alzheimer&apos s disease related dementia Area Caregivers Caring Categories Cause of Death Cessation of life Chronic Chronic Disease Clinical Collaborations Communication Communities Community Networks Complex Consent Data Data Set Dementia Dependence Development Disease Distress Educational workshop Elderly Enrollment Family Family Caregiver Fostering Foundations Funding Generations Grant Grant Review Health Services Research Healthcare Heart Diseases High Prevalence Improve Access Infrastructure Institution Investments K-Series Research Career Programs Knowledge Lead Leadership Longevity Measures Medical Education Medicine Mentorship Morbidity - disease rate National Institute on Aging Network Infrastructure Palliative Care Patients Persons Philanthropic Fund Physicians Population Population Growth Population Research Postdoctoral Fellow Program Reviews Public Health Quality of life Recommendation Recording of previous events Reporting Research Research Design Research Infrastructure Research Methodology Research Personnel Research Priority Research Project Grants Research Support Research Training Resources Science Scientist Societies Support System Surveys Talents United States United States National Institutes of Health Work Writing age group base behavioral health cancer risk care systems evidence base experience family support frailty human old age (65+)improved interest meetings multiple chronic conditions novel physical symptom population based programs psychological symptom psychosocial senior faculty skills support network virtual webinar

项目摘要

PROJECT SUMMARY Society is facing one of the largest public health challenges in its history - the growth of the population of older adults and increasing morbidity due to chronic serious illness. Over the next decades, most physicians will be caring for seriously ill older adults with physical and psychological symptom distress; progressive functional dependence and frailty; high family support needs; and escalating health care resource use. Indeed, the number of older adults with multiple chronic conditions is expected to increase by more than a third between 2000 and 2030 and those with dementia will nearly double. Abundant evidence suggests that the advanced stages of disease for most are characterized by inadequately treated physical distress; fragmented care systems; poor communication between doctors, patients, and families; and strains on family caregivers. The philanthropically funded National Palliative Care Research Center (NPCRC) has served as a collaborative mechanism for promoting interdisciplinary geriatric palliative care research since 2006. NPCRC was established to promote and develop palliative care research across the U.S. It addressed the National Academy of Medicine's recommendations to support a “cadre of experts whose numbers and talents are sufficient to: a) supply leadership for scientifically-based and practically useful medical education; and b) organize and conduct clinical, behavioral, and health services research for patients with serious and chronic illness.” The NPCRC, in collaboration with NIA, has established priorities for palliative care research, enhanced its evidence base, developed a new generation of researchers in palliative care, and created a national community of scientists. NPCRC has funded 100 interdisciplinary investigators (54 in aging research) from 46 institutions and 21 states along the continuum from junior to senior faculty and engaged in a broad spectrum of research dedicated to improving quality of life for persons living with serious illness. Our novel, research platform now forms the basis of our current R33 proposal to expand and enhance this research infrastructure. We will establish a new network of geriatric palliative care research trainees through collaboration across the palliative care focused post-doctoral programs in the U.S. For early-stage investigators, we will lead a research technical assistance program encompassing workshops and webinars on advanced statistical research methods, a grant writing (i.e., NIH K and R01 applications) skills workshop, and a grant review program. We will support new initiatives in dementia and population-based research and training. For experienced investigators, we will support the development and conduct of multisite collaborative geriatric palliative care research by supporting networking and project start-up meetings leading to multisite studies focusing on NIA research priorities in geriatric palliative care. Our proposal will advance research infrastructure that has successfully leveraged the NPCRC as the collaborative vehicle for interdisciplinary partnerships for geriatric palliative care research for trainees, junior, and experienced investigators across the U.S.

项目概要社会正面临着历史上最大的公共卫生挑战之一——人口的增长在接下来的几十年里，大多数医生认为老年人和慢性严重疾病导致的发病率不断增加。将照顾身体和心理症状逐渐恶化的重病老年人；事实上，功能依赖和虚弱；家庭支持需求增加；以及医疗资源的使用不断增加。患有多种慢性病的老年人数量预计将增加三分之一以上 2000 年至 2030 年间，患有痴呆症的人数将增加近一倍。大多数疾病晚期的特点是身体不适得到充分治疗；护理系统；医生、患者和家属之间的沟通不畅；以及家庭护理人员的压力。由慈善机构资助的国家姑息治疗研究中心 (NPCCRC) 已成为自2006年起促进跨学科老年姑息治疗研究的协作机制。NPCRC 成立的目的是在美国范围内促进和发展姑息治疗研究。医学科学院建议支持“数量和人才均符合要求的专家骨干队伍” 足以：a）为基于科学且实用的医学教育提供领导；b）为严重和慢性疾病患者组织和开展临床、行为和健康服务研究 NPCCRC 与 NIA 合作，确定了姑息治疗研究的优先事项，并加强了其证据基础，培养了新一代姑息治疗研究人员，并创建了国家 NPCCRC 已资助 46 名跨学科研究人员（其中 54 名从事衰老研究）。机构和 21 个州，从初级到高级教师，从事广泛的领域致力于改善患有严重疾病的人的生活质量的研究。我们新颖的研究平台现在构成了我们当前 R33 提案的基础，以扩展和增强这一点我们将通过建立一个新的老年姑息治疗研究实习生网络。美国以姑息治疗为重点的博士后项目之间的合作调查人员，我们将领导一项研究技术援助计划，包括以下方面的研讨会和网络研讨会先进的统计研究方法、资助写作（即 NIH K 和 R01 申请）技能研讨会以及我们将支持痴呆症和基于人群的研究和培训方面的新举措。对于经验丰富的研究人员，我们将支持多地点协作老年医学的开发和实施通过支持网络和项目启动会议进行姑息治疗研究，从而进行多站点研究重点关注 NIA 在老年姑息治疗方面的研究重点我们的提案将推进研究基础设施。已成功利用 NPCRC 作为跨学科伙伴关系的协作工具为美国各地的实习生、初级和经验丰富的研究人员进行老年姑息治疗研究