Core F -Integrated Support Services Core

核心 F - 综合支持服务核心

• 批准号: 10221399
• 负责人: JOAN E NICHOLS
• 金额: $ 64.1万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-31 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10221399
• 关键词: Address; Aerosols; Animal Model; Animals; Applied Research; Arthropod Vectors; Basic Science; Bioterrorism; Clinical Trials; Communicable Diseases; Containment; Dangerousness; Development; Diagnostic; Diagnostic tests; Disease; Emerging Communicable Diseases; Environment; Faculty; Funding; Goals; Human Resources; Infection; Institution; Investigation; Laboratories; Laboratory Animals; Licensure; Maintenance; Medical; Modeling; Mus; National Institute of Allergy and Infectious Disease; Postdoctoral Fellow; Protocols documentation; Reagent; Research; Research Activity; Research Infrastructure; Research Personnel; Research Support; Resources; Secure; Services; Site; Texas; Therapeutic; Training; Universities; Vaccines; Validation; Zoonoses; biodefense; biothreat; disease transmission; global health; imaging capabilities; laboratory experience; medical countermeasure; next generation; nonhuman primate; operation; pathogen; pre-doctoral; product development; programs; public health emergency; research facility; therapeutic development; therapy development; tool; vaccine evaluation; vector

Project Summary/Abstract The goal of this project is to maintain the Galveston National Laboratory (GNL) at the University of Texas Medical Branch as a part of the NIAID Biodefense Facilities Network to provide access to maximum containment research facilities for NIAID funded investigators, academic collaborators from across the nation and around the world, commercial partners and others as appropriate. This high containment research infrastructure and associated facilities is required to safely and securely conduct research that will facilitate the discovery and development of therapeutics, diagnostics and vaccines for dangerous pathogens requiring biocontainment. This unique resource is also a critical resource to educate the next generation of experts in infectious diseases of global health importance. The GNL actively responds to national public health emergencies by providing rapid assistance in diagnostics, sharing of critical reagents, and contributing to the discovery and development of effective medical countermeasures. To achieve this goal, the GNL maintains cores focused on supporting safe and secure operations and maintenance of maximum containment research facilities and to provide unique resources and tools to investigators working in biocontainment to allow them to rapidly, safely and securely address emerging infectious diseases and bioterrorism threats. Unique capabilities include the ability to generate and quantify aerosol challenges of laboratory animals from mice to non-human primates, access to arthropod vector colonies to support zoonotic disease transmission studies, and state-of-the-art imaging capabilities to visualize findings, among many others. Working together, GNL teams conduct basic and applied research that can transition original discoveries from concept to final product development, validation and licensure.

项目摘要/摘要 该项目的目的是维持加尔维斯顿国家实验室（GNL） 德克萨斯大学医学分公司作为NIAID Biodefense设施网络的一部分 为NIAID资助提供最大的遏制研究设施 调查员，来自全国和世界各地的学术合作者， 商业伙伴和其他人适当。这项高遏制研究 需要安全，安全地进行基础设施和相关设施 将促进治疗剂发现和开发诊断的研究 以及需要生物植物的危险病原体的疫苗。这个独特的资源 也是教育下一代传染病专家的关键资源 全球健康重要性的疾病。 GNL积极回应国家公众 健康紧急情况通过在诊断方面提供快速帮助，共享关键 试剂，并为有效医学的发现和开发做出贡献 对策。为了实现这一目标，GNL保持着专注于支持的核心 安全可靠的操作以及维护最大遏制研究 设施并为工作的调查人员提供独特的资源和工具 生物内在允许他们快速，安全，安全地解决新兴 传染病和生物恐怖主义威胁。独特的功能包括 从小鼠到非人类的实验动物产生和量化的气溶胶挑战 灵长类动物，进入节肢动物矢量菌落以支持人畜共患病传播 研究和最先进的成像功能可视化发现 其他的。 GNL团队共同努力，进行基础和应用研究 过渡从概念到最终产品开发，验证和 许可。