Pre-doctoral Training in Fundamental Approaches to Biochemistry and Cell and Molecular Biology

生物化学、细胞和分子生物学基础方法的博士前培训

• 批准号: 10205194
• 负责人: Stephen P. Bell
• 金额: $ 146.29万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10205194
• 关键词: Biochemistry; Cellular biology; Molecular Biology; Training; pre-doctoral

This proposal is for support of the pre-doctoral program in Cellular, Biochemical and Molecular Science at the Massachusetts Institute of Technology (MIT). Our mission is to train the next generation of biological/biomedical scientists, many of whom will be innovators and leaders in research, education, and other fields. This proposal builds on an outstanding training record developed over a 46-year partnership with NIGMS. Our aims are to: educate students to understand the fundamental and underlying principles of molecular, biochemical, and cellular biology, train students to be critical and creative thinkers, prepare students to be ethical decision makers, teach and provide practice in written and oral communication, provide experience with teaching and mentoring younger students, mentor students to become effective and rigorous researchers, guide students through completion and publication of research projects, advise students as they determine the best-fit careers for their interests and skills, provide an inclusive learning and research environment, and broaden participation of individuals with diverse backgrounds in biomedical research careers. We recruit and train talented students from majority, underrepresented minority, disabled, and disadvantaged populations. Trainees admitted to our program have outstanding academic records and strong motivation and aptitude to pursue research. A key feature of our program is an intensive, focused curriculum required of all first-year students. Students work together in lecture and discussion-style courses taught by dedicated faculty to master a fundamental set of approaches that underpin molecular biological science. The training program exposes students to the research interests of all faculty members in the Biology Department prior to a sequence of rotations that, in combination with first-semester courses, support an informed choice of a thesis advisor and topic. Students gain experience in scientific communication and in teaching and mentoring junior students. Responsible conduct of research is taught in both classroom and laboratory settings, including an intense mini-course for 2nd year students. Students have many opportunities to learn about career paths open to them following doctoral training. Students’ progress through the program is monitored in regular thesis committee meetings with faculty members, with oversight by the graduate committee. We seek to build and maintain a welcoming and supportive community in which all students are valued and included. This training grant would constitute a critical source of support for ~50% of training-grant eligible graduate students in our program during their first two years. Our students perform research of outstanding quality, and most trainees go on to careers in biomedical research. Many of our former trainees are now leaders in their chosen fields and bring to their positions the knowledge, rigor, thoughtful perspectives, and values of equity and inclusion that we emphasize at MIT Biology. We anticipate exciting futures for our alumni as they help transform the US biomedical landscape.

该提案旨在支持细胞、生化和分子科学领域的博士前项目 麻省理工学院（MIT）的使命是培养下一代。 生物/生物医学科学家，其中许多人将成为研究、教育和研究领域的创新者和领导者 该提案建立在与 46 年合作伙伴关系中所取得的杰出培训记录的基础上。 我们的目标是： 教育学生了解 NIGMS 的基本原则。 分子、生物化学和细胞生物学，培养学生成为批判性和创造性的思考者，做好准备 学生成为有道德的决策者，教授并提供书面和口头交流的实践，提供 具有教学和指导年轻学生的经验，指导学生变得有效和严谨 研究人员，指导学生完成和发表研究项目，为学生提供建议 确定最适合他们的兴趣和技能的职业，提供包容性的学习和研究 环境，并扩大具有不同背景的个人对生物医学研究的参与 我们招收和培训来自多数群体、少数族裔、残疾人和有才华的学生。 录取我们项目的弱势群体学员学业成绩优异，实力雄厚。 追求研究的动机和能力 我们项目的一个关键特点是密集、重点突出的课程。 所有一年级学生都需要一起学习由教授教授的讲座和讨论式课程。 专门的教师掌握支持分子生物科学的一套基本方法。 培训计划让学生了解生物系所有教员的研究兴趣 在一系列轮换之前，结合第一学期的课程，支持明智的选择 论文导师和主题的学生获得科学传播以及教学和主题方面的经验。 课堂导师和实验室均教授负责任的研究行为 环境，包括为二年级学生提供的密集迷你课程，学生有很多学习机会。 关于学生在该计划中取得的进展的职业道路。 在研究生的监督下，在与教职人员的定期论文委员会会议上进行监督 我们致力于建立和维持一个欢迎和支持所有学生的社区。 这笔培训补助金将构成约 50% 培训补助金的重要支持来源。 符合条件的研究生在我们项目的头两年进行研究。 优秀的品质，大多数学员继续从事生物医学研究。 现在是他们所选择领域的领导者，并将知识、严谨、深思熟虑带到他们的岗位上 我们在麻省理工学院生物学所强调的观点以及公平和包容的价值观我们期待令人兴奋的事情。 我们校友的未来，因为他们帮助改变了美国的生物医学格局。