Administrative Core

行政核心

基本信息

批准号：
10356725
负责人：
MANISH J BUTTE
金额：
$ 21.84万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-01-24 至 2026-12-31
项目状态：
未结题

项目摘要

Summary This Administrative Core fosters our coalition of clinicians and scientists across the six institutions of our Coccidioidomycosis Collaborative Research Center (CCRC) and aligns our activities to the priorities established by the NIH for this program. To manage our activities, we propose this Administrative Core to interface with each Core and Project and with NIAID/NIH Program Officers. This core will be directed by the UCLA MPI (Butte) and the UCSD MPI (Hoffman), and managed by Alexis Stephens, Clinical Research Coordinator, UCLA Division of Immunology. The administrative duties of this core include management of resources, implementation of policies and best practices, arranging the timely flow of clinical samples, coordination of communications and publications, and storage and sharing of data. The overall goals are to maximize the productive research potential of all Projects and Cores, and ensure the timely completion of goals of this program. In Aim 1, we provide infrastructure support to ensure completion of all research objectives. We will Develop a management plan (leadership and staff), develop an organizational structure and regular meetings, including monthly, quarterly, and Annual Meetings. We will also establish an External Advisory Board in consultation with the NIAID. We will establish a conflict resolution system. We will ensure regulatory compliance and maintain records for all Projects and Cores. An innovative part of this proposal is the development of a LabKey database to track all clinical phenotypes, genomics, and results. Finally, we will ensure close involvement with NIAID. In Aim 2, we provide support for fiscal management and reporting. The Administrative Core will coordinate Principal Investigators and Key Personnel and will organize communications, group meetings, teleconferences, and publications. The Administrative Core will track funds and expenses across all sites In Aim 3, we Establish the Development Research Program, including its administration and the mentoring roles.

概括该行政核心促进了我们六个机构的临床医生和科学家的联盟球孢子菌病合作研究中心 (CCRC) 并使我们的活动与既定的优先事项保持一致由美国国立卫生研究院 (NIH) 负责该计划。为了管理我们的活动，我们建议建立这个管理核心来与每个核心和项目以及 NIAID/NIH 项目官员。该核心将由 UCLA MPI (Butte) 指导， UCSD MPI (Hoffman)，由 UCLA 部门临床研究协调员 Alexis Stephens 管理免疫学。该核心的行政职责包括资源管理、政策执行和最佳实践，安排临床样本的及时流动，协调沟通和出版物以及数据的存储和共享。总体目标是最大限度地提高研究成果发挥所有项目和核心的潜力，并确保按时完成该计划的目标。在目标 1 中，我们提供基础设施支持以确保完成所有研究目标。我们将发展管理计划（领导层和员工），制定组织结构和定期会议，包括月度、季度和年会。我们还将与各方协商建立外部顾问委员会国家过敏和传染病研究所。我们将建立冲突解决制度。我们将确保遵守法规并维护所有项目和核心的记录。该提案的一个创新部分是开发 LabKey 数据库跟踪所有临床表型、基因组学和结果。最后，我们将确保与 NIAID 的密切参与。在目标 2 中，我们为财务管理和报告提供支持。行政核心将协调首席研究员和关键人员将组织沟通、小组会议、电话会议、和出版物。管理核心将跟踪所有站点的资金和支出在目标 3 中，我们建立发展研究计划，包括其管理和指导角色。